Results 21 to 30 of about 98,826 (250)

Current Management and Treatment of Dry Eye Disease [PDF]

open access: yes, 2018
A better understanding of the pathophysiology and etiology of dry eye disease leads to more efficient management and treatment of the disease process.
Cem Şimşek   +3 more
core   +1 more source

Diagnosis and Treatment of Dry Eye

open access: yes, 2021
Dry Eye Disease is a common disorder of the ocular surface which affects millions of people with varying severity. Untreated dry eye disease results in inflammation, corneal surface abrasion, corneal ulcers even vision loss.Current diagnosis of the dry ...
Basar, Oguzhan
core  

Ocular Findings of Pediatric Dry Eye Related to Graft-Versus-Host Disease [PDF]

open access: yes, 2021
Objectives:To evaluate the frequency and findings of dry eye associated with ocular graft-versus-host disease (GVHD) in pediatric hematopoietic stem cell transplantation (HSCT) patients.Materials and Methods:Retrospectively the records of pediatric ...
Elif İnce   +6 more
core   +1 more source

Degradation mechanism of the von Willebrand factor A2 domain by nattokinase

open access: yesFEBS Letters, EarlyView.
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto   +3 more
wiley   +1 more source

Dry Eye Disease after Cataract Surgery: Study of its Determinants and Risk Factors

open access: yes, 2020
Objectives:To study the incidence of dry eye and its determinants in patients undergoing cataract surgery.Materials and Methods:One hundred twenty patients with senile cataract underwent Schirmer’s test, tear break-up time (TBUT) test, lissamine green ...
Nishi Tandon   +3 more
core   +1 more source

Long‐term hippocampal alterations and cognitive impairment in a murine model of surgical sepsis

open access: yesFEBS Open Bio, EarlyView.
Using a mouse model of surgical sepsis, we tested long‐term memory and analyzed the transcriptome of single cells isolated from the hippocampus. Survivor mice showed worse memory, loss of certain brain cell subpopulations, and abnormal immune cell activity—suggesting that post‐sepsis brain alterations may be linked to cognitive deficits.
Dong Seong Cho   +4 more
wiley   +1 more source

Derivation and characterization of retinal pigment epithelium from urine‐derived iPSCs

open access: yesFEBS Open Bio, EarlyView.
Age‐related macular degeneration causes vision loss via RPE dysfunction and loss. Traditional iPSC therapies rely on invasive biopsies, limiting scalability. Here, we utilize urine‐derived stem cells as an accessible source to generate u‐iPSCs, successfully differentiated into pigmented RPE. This “Urine‐to‐Retina” platform provides a promising path for
Daniella Beiner   +7 more
wiley   +1 more source

Meibomian Gland Dropout in Patients with Dry Eye Disease in China

open access: yes, 2014
Purpose: To examine the morphological changes in the meibomian glands of eyes of patients with dry eye disease using the non-contact infrared meibography system and to assess their relationship with meibomian dropout, signs, and tear-film function ...
Gao, Ziqing   +4 more
core   +1 more source

Recurrent Hypothermia and Autonomic Dysfunction Secondary to Shapiro Syndrome

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT A 44‐year‐old man presented with recurrent hypothermia, diaphoresis and hypertension. Extensive investigation for infectious, inflammatory, metabolic and endocrine aetiologies was negative. MR scan of the brain demonstrated no lesions but revealed callosal dysgenesis, consistent with Shapiro syndrome.
Naveen Kumar   +3 more
wiley   +1 more source

Dry eye and systemic diseases

open access: yesSaudi Journal of Ophthalmology
Abstract: Tear film instability and reduced tear production initiate a vicious circle where hyperosmolarity, ocular inflammation, and apoptosis may induce a damage of the ocular surface including keratitis which is all included in a common condition called dry eye disease (DED).
Leonardi, Andrea   +3 more
openaire   +2 more sources

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