Results 31 to 40 of about 6,747,004 (260)

Electronics-Free Visual Monitoring of Dry Eye Disease-Related Tear Biomarkers Using Smart Scleral Lenses. [PDF]

Adv Sci (Weinh)
An electronics‐free smart scleral lens passively monitors dry eye disease‐related tear biomarkers through colorimetric sensing of chloride, pH, and ocular surface temperature. Smartphone‐assisted image analysis enables quantitative interpretation, providing a simple, non‐invasive strategy for ocular health monitoring without integrated electronics ...
Wang Z, Park SM, Meyer D, Lee SA, Dai Y, Yu T, Park T, Li F, Jedlicka JG, Long TM, Oladele OT, Shaw GC, Park SA, Kollbaum PS, Kim YL, Lee CH.   +15 more
europepmc   +2 more sources

Experimental Pharmacotherapy for Dry Eye Disease: A Review [PDF]

, 2021
Monica Baiula, Santi Spampinato Department of Pharmacy and Biotechnology, University of Bologna, Bologna, ItalyCorrespondence: Santi SpampinatoDepartment of Pharmacy and Biotechnology, University of Bologna, via Irnerio 48, Bologna, ItalyTel +39 ...
Spampinato S, Baiula M, Baiula M., Spampinato S., Monica Baiula, Santi Spampinato   +5 more
core   +1 more source

L‐aspartate oxidase provides new insights into fumarate reduction in anaerobic darkness in Synechocystis sp. PCC6803

FEBS Letters, EarlyView.
Synechocystis strains deficient in succinate dehydrogenase (SDH) secrete more succinate than the WT under dark anaerobic conditions, supporting that SDH then primarily acts as SDH, not as a fumarate reductase. L‐aspartate oxidase (Laspo) from Synechocystis is functional under anaerobic conditions, reducing fumarate to succinate.
Kateryna Kukil, Jeffrey A. Hawkes, Cecilia Blikstad, Pia Lindberg   +3 more
wiley   +1 more source

Prevalence and risk factors for dry eye disease: the Sao Paulo dry eye study

, 2022
Purpose: To estimate the prevalence and risk factors of dry eye disease symptoms and clinical diagnoses in Sao Paulo city, state of Sao Paulo, Brazil.
Leonardo Guedes C. Marculino (12684729), Flavio Hirai (12684738), Jose Arthur P. Milhomens Filho (12684741), Tais Hitomi Wakamatsu (12684744), José A.P. Gomes (12684747), Rossen Mihaylov Hazarbassanov (12684732), Nicolle Gilda Teixeira de Queiroz Hazarbassanov (12684735)   +6 more
core   +2 more sources

The Relation between Serum Level of Vitamin D and Dry Eye Disease [PDF]

, 2017
Purpose: To investigate the relation between serum level of vitamin D and dry eye disease. Patients and Methods:  In this cross-sectional case-control study, 40 patients with dry eye disease were enrolled.
Amizadeh, Yashar, Shahraki, Kianoosh, Feizi, Sepehr, Abbasi, Hamed, Shahraki, Kourosh, Seifi, Mohammadhasan, Daneshtalab, Arash, Shojaei, Ahmad   +7 more
core   +1 more source

Avidin is evolutionarily conserved in fish but dispensable for development and resistance against Streptococcus agalactiae in zebrafish

FEBS Open Bio, EarlyView.
The presence of biotin‐binding avidin proteins in fish and their biological significance are poorly characterized. We cataloged fish avidins and demonstrate that they are widely present and evolutionarily conserved. We created avd knockout zebrafish and show that zebavidin is dispensable for development and that resistance of avd knockout embryos in ...
Anni K. Saralahti, Markus J. T. Ojanen, Mataleena Parikka, Otto Kauko, Mika Rämet, Vesa P. Hytönen   +5 more
wiley   +1 more source

Risk factors of dry eye disease (DED) according to the Dry Eye Syndrome Questionnaire used in the Women’s Health Study (WHS) and the Ocular Surface Disease Index (OSDI).

, 2021
Risk factors of dry eye disease (DED) according to the Dry Eye Syndrome Questionnaire used in the Women’s Health Study (WHS) and the Ocular Surface Disease Index (OSDI).
Pedro Albuquerque Rebello (11681976), Gabriel Ayub (11681973), Monica Alves (567235), Isabela Yang (11681958), José Álvaro Pereira Gomes (4656598), Tais Wakamatsu (11681961), José Henrique Fazzi (11681967), Isabella Batistela Inhesta Sacho (11681964), Asafe César de Aquino (11681970)   +8 more
core   +1 more source

GelMA‐based 3D spheroids recapitulate transcriptomic and functional hallmarks of myeloid sarcoma

FEBS Open Bio, EarlyView.
GelMA 5% hydrogels support the formation of myeloid leukemia spheroids that recapitulate MS‐specific features, including G1 arrest, apoptosis, and ECM‐driven transcriptomic reprogramming. The 3D model mimicked soft‐tissue‐like stiffness and oxygen conditions, and transcriptomic convergence with primary MS samples confirmed its utility as a preclinical ...
Nicolas Germain, Elise Buret, Le Hoang Thanh Nguyen, Marion Cocheteux, Nicolas Touya, Mélanie Dhayer, Romain Dubois, Frank Lafont, Sebastien Janel, Patrice Maboudou, Steve Lancel, Philippe Marchetti   +11 more
wiley   +1 more source

MARK4 enhances stress granule formation under oxidative stress and increases tau accumulation

FEBS Open Bio, EarlyView.
MARK4 (red dots) localizes to stress granules (orange dots) and promotes their formation under oxidative stress by modulating TIA1 (blue dots). MARK4 and TIA1 synergistically increase tau (purple) accumulation, and the reduction of the TIA1 ortholog suppresses neurodegeneration in a fly model.
Sho Nakajima, Kotone Watanabe, Grigorii Sultanakhmetov, Aoi Fukuchi, Keiya Ito, Sawako Shimizu, Taro Saito, Akiko Asada, Kanae Ando   +8 more
wiley   +1 more source

Randomized, crossover clinical efficacy trial in humans and mice on tear secretion promotion and lacrimal gland protection by molecular hydrogen

Scientific Reports, 2021
The incidence of dry eye disease is increasing worldwide because of the aging population and increasing use of information technology. Dry eye disease manifests as tear-layer instability and inflammation caused by osmotic hypersensitization in tear ...
Miyuki Kubota, Motoko Kawashima, Sachiko Inoue, Toshihiro Imada, Shigeru Nakamura, Shunsuke Kubota, Mitsuhiro Watanabe, Ryo Takemura, Kazuo Tsubota   +8 more
doaj   +1 more source