Results 61 to 70 of about 108,243 (386)

Advancing Clinical Medicine with Raman Spectroscopy: Current Trends and Future Perspectives

open access: yesAdvanced Photonics Research, EarlyView.
Raman spectroscopy and microscopy may become excellent tools in clinical medicine, including hematology, oncology, infectious diseases, neurology, gastroenterology, reproductive medicine, rheumatology, and cardiovascular research. However, many challenges such as signal interference, standardization issues, and limited clinical application need to be ...
Jiří Bufka   +5 more
wiley   +1 more source

Dry eye disease in patients with metabolic syndrome [PDF]

open access: yesSaudi Medical Journal, 2016
To evaluate dry eye disease (DED) in patients with metabolic syndrome (MetS) and compare with healthy individuals.The study was conducted in the Ophthalmology and Endocrinology Department of Bagcilar Education and Research Hospital, a tertiary care center in Istanbul, Turkey, between January and December 2015. In this prospective case-controlled study,
Kubra Serefoglu Cabuk   +4 more
openaire   +2 more sources

Nicotine Reprograms Aging‐Related Metabolism and Protects Against Motor Decline in Mice

open access: yesAdvanced Science, EarlyView.
Long‐term oral nicotine intake protects against age‐related motor decline in mice without eliciting systemic toxicity. Integrated multi‐organ metabolomic profiling and longitudinal gut microbiota analyses reveal that nicotine induces coordinated remodeling of glycolipid and sphingolipid metabolism, enhances NAD⁺ bioavailability, and suppresses ceramide
Shuhui Jia   +29 more
wiley   +1 more source

Tear fluid biomarkers in ocular and systemic disease: potential use for predictive, preventive and personalised medicine [PDF]

open access: yes, 2016
In the field of predictive, preventive and personalised medicine, researchers are keen to identify novel and reliable ways to predict and diagnose disease, as well as to monitor patient response to therapeutic agents.
A Acera   +183 more
core   +2 more sources

Angiogenin for the Diagnosis and Grading of Dry Eye Syndrome [PDF]

open access: yesKorean Journal of Ophthalmology, 2016
To investigate the properties of angiogenin (ANG) as a potential tool for the diagnosis and grading of dry eye syndrome (DES) by analyzing tear protein profiles.Tear samples were collected with capillary tubes from 52 DES patients and 29 normal individuals as controls. Tear protein profiles were analyzed with an immunodot blot assay as a screening test.
Won Soo Kim   +3 more
openaire   +3 more sources

Sleep Deprivation Aggravates Periodontitis Through Trigeminal‐Periodontal Neuroimmune Pathway Mediated by the AChE‐ACh‐α7nAChR Axis

open access: yesAdvanced Science, EarlyView.
Sleep deprivation (SD) exacerbates ligature‐induced periodontitis (LIP) through the trigeminal nerve‐periodontal neuroimmune pathway mediated by the acetylcholinesterase (AChE)‐acetylcholine (ACh)‐α7 nicotinic receptor (α7nAChR) axis. While electroacupuncture (EA) alleviates the condition of LIP combined with SD by activating the α7nAChR.
Kehao Liu   +13 more
wiley   +1 more source

Effectiveness of using preservative-free artificial tears versus preserved lubricants for the treatment of dry eyes: a systematic review.

open access: yesArquivos Brasileiros de Oftalmologia, 2019
This systematic review aimed to assess the effectiveness of using preservative-free artificial tears versus preserved lubricants for the treatment of dry eyes in Universidade Federal de Alagoas (PROSPERO 2018 CRD42018089933).
Marina Viegas Moura Rezende Ribeiro   +4 more
semanticscholar   +1 more source

RIPK1 Drives JAK1‐STAT3 Signaling to Promote CXCL1‐Mediated Neutrophil Recruitment in Sepsis‐Induced Lung Injury

open access: yesAdvanced Science, EarlyView.
This article examines the central role of RIPK1 in the pathogenesis of sepsis‐induced lung injury. It elucidates how RIPK1 initiates an inflammatory cascade by activating JAK1‐STAT3 signaling, leading to CXCL1‐mediated neutrophil infiltration. Importantly, it demonstrates that pharmacological inhibition of RIPK1 effectively attenuates inflammation and ...
Hao Sun   +15 more
wiley   +1 more source

Topical applications of allogeneic adipose-derived mesenchymal stem cells ameliorate the canine keratoconjunctivitis sicca

open access: yesBMC Veterinary Research, 2022
Background Canine keratoconjunctivitis sicca (KCS) is predominantly an immune-mediated disease. Current therapy of canine KCS is mainly by immunosuppressant, but the effectiveness was limited in some patients.
Li-Ning Wei   +3 more
doaj   +1 more source

Risk factors for obstructive sleep apnea syndrome in children: state of the art [PDF]

open access: yes, 2019
The obstructive sleep apnea syndrome (OSAS) represents only part of a large group of pathologies of variable entity called respiratory sleep disorders (RSD) which include simple snoring and increased upper airway resistance syndrome (UARS).
Bellini, Chiara   +16 more
core   +2 more sources

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