Results 81 to 90 of about 108,243 (386)

Symptoms and signs in rigid gas permeable lens wearers during adaptation period [PDF]

open access: yes, 2016
Objectives: To evaluate neophyte contact lens wearers’ fitting to rigid gas permeable (RGP) contact lenses in terms of wearing time, tear volume, stability, corneal staining, and subjective ratings, over a 1-month period of time.
Abejón-Gil, Pilar   +5 more
core   +1 more source

Pathophysiology of dry eye syndrome

open access: yesActa Ophthalmologica, 2010
AbstractDry eye or dysfunctional tear syndrome is a highly prevalent disease worldwide. It is related to a pathological condition of anyone of the parts of the “ocular surface system” that involves the cornea, conjunctiva, lacrimal gland, accessory lacrimal glands, nasolacrimal duct and the lids with the meibomian glands.
openaire   +2 more sources

Management of Dry Eye in Sjögren’s Syndrome [PDF]

open access: yesCurrent Treatment Options in Rheumatology, 2015
The treatment of dry eye in Sjogren’s syndrome varies based on the severity of the disease. First-line therapy usually includes environmental changes and lubrication of the ocular surface with the use of artificial tears and/or ointments. Punctal occlusion may also help by extending available lubrication via natural or artificial tears.
Michelle Hessen   +2 more
openaire   +2 more sources

Diagnosis and Treatment of Ocular Pain: the Ophthalmologist’s Perspective

open access: yesCurrent Ophthalmology Reports, 2017
Purpose of ReviewThe aim of this review is to help ophthalmologists and other clinicians understand and treat ocular neuropathic pain.Recent FindingsAdvances in the field of neurophysiology of ocular sensations explain why some cases of dry eye may ...
D. Jacobs
semanticscholar   +1 more source

Identification and Characterization of a Novel Biallelic SLC12A2 Variant Associated With Kilquist Syndrome (OMIM #619080)

open access: yesAmerican Journal of Medical Genetics Part A, EarlyView.
ABSTRACT This study presents the case of a child with multiple congenital anomalies, severe hypotonia, and profound bilateral sensorineural hearing loss. Functional bioenergetic assessments showed no significant mitochondrial respiratory defects, and riboflavin (Rf) status evaluation excluded a deficiency in Rf transporters as a cause of hearing loss ...
Piero Leone   +13 more
wiley   +1 more source

Health claims database study of cyclosporine ophthalmic emulsion treatment patterns in dry eye patients

open access: yesTherapeutics and Clinical Risk Management, 2013
Karl G Stonecipher,1 Jenny Chia,2 Ahunna Onyenwenyi,2 Linda Villanueva,2 David A Hollander2 1TLC Laser Eye Centers, Greensboro, NC, 2Allergan, Inc., Irvine, CA, USA Background: Dry eye is a multifactorial, symptomatic disease associated with ocular ...
Stonecipher KG   +4 more
doaj  

The tear film and ocular mucins

open access: yesVeterinary Ophthalmology, 2004
The trilaminar tear film, composed of the lipid, aqueous and mucin layers, has many functions including defending the ocular surface. The aqueous layer has several soluble antimicrobial factors that protect the ocular surface. Ocular mucins have recently
H. Davidson, V. Kuonen
semanticscholar   +1 more source

Regulatory Role of FGL‐1 in Interorgan Communication by Controlling T Cell Homeostasis During the Onset of Sjögren Disease

open access: yesArthritis &Rheumatology, EarlyView.
Objective Autoimmunity occurs due to the tactics between pathogenic and regulatory factors in systemic organs. Although interorgan communication has been demonstrated in various diseases, the effects of the crosstalk between the immune system and other organs on autoimmune disease is unknown.
Kunihiro Otsuka   +8 more
wiley   +1 more source

Dry eye syndrome: a disease of the civilization. diagnosis and treatment options

open access: yesМедицинский совет, 2013
For many years now dry eye syndrome (DES) characterized by relatively high prevalence in the population of developed countries remains a challenge for practical medicine. The prevalence of DES continues to grow. According to the studies of R.
V. V. Brzhesky
doaj   +1 more source

Sjögren Disease—B Cells at the Brink: From Autoimmunity to Lymphomagenesis and the Rise of Novel B Cell‐Targeted Therapies

open access: yesArthritis &Rheumatology, Accepted Article.
Sjögren disease (SjD) is a common systemic autoimmune disorder characterized by inflammation of the exocrine glands, resulting in dryness. Patients frequently exhibit extraglandular manifestations affecting various organ systems. To date, there are no FDA‐approved disease‐modifying therapies for SjD.
Rachael A. Gordon, Sara S. McCoy
wiley   +1 more source

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