Results 71 to 80 of about 532,660 (264)

Mass spectrometry based identification of AMP‐O‐Tris generated by Thermococcus onnurineus Cas10

FEBS Open Bio, EarlyView.
Isolated Thermococcus onnurineus Cas10 generates the noncanonical ATP‐derived product AMP‐O‐Tris while in Tris‐containing buffer as identified via mass spectrometry, revealing relaxed nucleophile selectivity under isolated conditions. These findings suggest that multiprotein Csm complex assembly restricts Cas10 reactivity toward canonical cyclic ...
Su‐Jin Lee, Ga Seul Lee, JinHan Kim, Kwang‐Hyun Park, Seong‐Ryung Go, Jeong Hee Moon, Eui‐Jeon Woo   +6 more
wiley   +1 more source

Suscetibilidade de cultivares de arroz irrigado (Oryza sativa) à deriva simulada do herbicida imazethapyr + imazapic Susceptibility of rice cultivars (Oryza sativa) to simulated drift of the herbicide imazethapyr + imazapic

Planta Daninha, 2006
Objetivou-se neste trabalho avaliar a suscetibilidade dos cultivares de arroz irrigado IRGA 417, BR-IRGA 410, BRS Pelota e Qualimax 1 à simulação de deriva do herbicida imazethapyr + imazapic em função da época de início da irrigação por inundação.
T. Dal Magro, J.J.O. Pinto, D. Agostinetto, L. Galon, A.L. Rezende, C.A. Lazarotto   +5 more
doaj   +1 more source

Derivation and characterization of retinal pigment epithelium from urine‐derived iPSCs

FEBS Open Bio, EarlyView.
Age‐related macular degeneration causes vision loss via RPE dysfunction and loss. Traditional iPSC therapies rely on invasive biopsies, limiting scalability. Here, we utilize urine‐derived stem cells as an accessible source to generate u‐iPSCs, successfully differentiated into pigmented RPE. This “Urine‐to‐Retina” platform provides a promising path for
Daniella Beiner, Hainan Zhu, Carol Christine Bosholm, Heuy‐Ching Wang, Tracy Criswell, Anthony Atala, Jian‐Xing Ma, Yuanyuan Zhang   +7 more
wiley   +1 more source

Pharmacological inhibition of the PERK pathway modulates hepatocellular carcinoma growth and immune signaling

FEBS Open Bio, EarlyView.
Pharmacological inhibition of PERK in a DEN‐induced mouse model of liver cancer does not reduce tumor burden but alters cellular stress signaling. Despite blocking PERK activity, downstream stress responses, including CHOP expression, remain active, suggesting compensatory mechanisms within the unfolded protein response that may influence tumor ...
Ada Lerma‐Clavero, Maria Kopsida, Nathalie Arendt, Hans Lennernäs, Markus Sjöblom, Femke Heindryckx   +5 more
wiley   +1 more source

Crescimento e produtividade de plantas de tomateiro em cultivo protegido sob alta densidade e desfolhamento Growth and fruit yield of greenhouse tomato plants under high plant density and defoliation

Ciência Rural, 2004
O objetivo do trabalho foi determinar o efeito do aumento da densidade de plantas combinada com desfolhamento sobre o crescimento e a produtividade do tomateiro cultivado no solo em ambiente protegido.
Jerônimo Luiz Andriolo, Maria Carolina Grigoletto Espindola, Rodrigo Godoi, Orcial Ceolin Bortolotto, Gean Lopes da Luz   +4 more
doaj   +1 more source

A yeast model of 5‐oxoproline accumulation reveals a general toleration to 5‐oxoproline

FEBS Open Bio, EarlyView.
Using a yeast model, we show that even high accumulation of 5‐oxoproline causes only mild cellular stress and does not trigger oxidative stress. Instead, cells adapt by activating efflux pumps and diverse protective pathways, suggesting that previously proposed harmful effects of 5‐oxoproline may arise from indirect metabolic imbalances rather than the
Pratiksha Dubey, Vaishnavi Sanjayan, Praveen Singh, Shantanu Sengupta, Anand Kumar Bachhawat   +4 more
wiley   +1 more source

Effect of Saline Irrigation on Accumulation of Na+, K+, Ca2+, and Mg2+ Ions in Rice Plants

Agriculture, 2018
Salinity is an abiotic stress that curtails rice production in many parts of the world. Although Koshihikari and Nikomaru are high-yielding japonica rice cultivars, their salinity-tolerance levels are not well known.
Mahjuba Akter, Hiroki Oue
doaj   +1 more source

Mass Transfer Properties of Pears for Different Drying Methods

International Journal of Food Properties, 2013
In the present work, the mass transfer properties of pears were determined for three different drying systems (a solar stove, a direct solar drier, and a drying tunnel), using three calculation methodologies. The results obtained allowed concluding that the best methodology to calculate the mass transfer properties is based on Fick's equation ...
Guiné, Raquel, Barroca, Maria João, Silva, Vítor   +2 more
openaire   +2 more sources

RoundMi: A quantitative method to analyze mitochondrial morphology in mitotic cells

FEBS Open Bio, EarlyView.
RoundMi is a workflow for rapid analysis of mitochondrial morphology in mitotic cells. By combining adaptive preprocessing with automated segmentation and quantification, it enables accurate measurements from single focal plane images, reducing acquisition time and computational demands while remaining compatible with high‐throughput fixed and live ...
Elmira Parvindokht Bararpour, Christine Volmert, Valentina Piano   +2 more
wiley   +1 more source

Time‐restricted feeding prior to Mycobacterium tuberculosis infection reduces tissue CD4+ T cells with limited impact on bacterial clearance

FEBS Open Bio, EarlyView.
Time‐restricted feeding (TRF) in mice increased liver fatty acid oxidation and decreased fatty acid biosynthesis. These alterations persisted when TRF was discontinued and the host was infected with Mycobacterium tuberculosis. Pre‐exposure to TRF did not alter tissue (lung and spleen) mycobacterial burden but significantly reduced CD3+ T cells in lungs
Ashish Gupta, Nidhi Yadav, Subhasmita Das, R. Rajendra Kumar Reddy, Nupur Sharma, Amol Ratnakar Suryawanshi, Jaswinder Singh Maras, Ranjan Kumar Nanda   +7 more
wiley   +1 more source