Results 51 to 60 of about 532,660 (264)
Molecular Oncology, EarlyView.Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano +6 more
wiley +1 more source
Agronomy Science, 2019 The aim of this study was to determine the effect of spraying the nano-boron on the concentration of certain nutrients, chlorophyll in the leaves and dry matter of plants of two faba bean cultivars.
ALI HULAIL NOAEMA +3 more
doaj +1 more source
Molecular Oncology, EarlyView.Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla +9 more
wiley +1 more source
Selected properties of agricultural biomass
Research in Agricultural Engineering, 2013 The presented contribution deals with the quantification of moisture, combustible matter content, ash content and higher heating value of the selected types of biomass used for the heat production by direct combustion.
V. Kažimírová +2 more
doaj +1 more source
Hybrid Rockets as Post-Boost Stages and Kick Motors
Aerospace, 2021 Hybrid rockets are attractive as post-boost stages and kick motors due to their inherent safety and low cost, but it is not clear from previous research which oxidizer is most suitable for maximizing ΔV within a fixed envelope size, or what impact O/F ...
Landon Kamps +2 more
doaj +1 more source
CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3
Molecular Oncology, EarlyView.PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh +12 more
wiley +1 more source
Molecular Oncology, EarlyView.EXOSC10, an essential nuclear RNA exosome‐associated 3′‐5′ exoribonuclease, is inhibited by the anticancer drug 5‐fluorouracil (5‐FU), and EXOSC10 depletion increases 5‐FU sensitivity. The colon‐cancer variant EXOSC10S402T, located in a proteolysis motif, is stable and nuclear but nonfunctional in vivo.
Radhika Sain +10 more
wiley +1 more source
Drying Kinetics and Modelling of Mass Transfer in Thin Layer Convective Drying of Pineapple [PDF]
Chemical Science International Journal, 2017 The aim of the investigation was to study the drying characteristics of pineapple at different temperatures of 55, 60, 65, 70 and 75°C with 1.5 m/ s constant air velocity. In the present study, the best drying model was selected to describe the drying behaviour, and to develop the moisture profile using COMSOL.
Ravula Sudharshan Reddy +4 more
openaire +2 more sources
Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining
Molecular Oncology, EarlyView.IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis +3 more
wiley +1 more source
Spanish Journal of Agricultural Research, 2014 The effect of olive mill wastewater (OMW) on growth of tulip plants infected by common diseases as well as on their new bulbs production is analyzed in this work.
Christos Lykas +2 more
doaj +1 more source