Results 51 to 60 of about 1,966,339 (283)

Pilot Study on the Forehead Skin Microbiome and Short Chain Fatty Acids Depending on the SC Functional Index in Korean Cohorts

Microorganisms, 2021
Dry skin is one of the indicators of a compromised skin barrier. An intact skin barrier is not only important to reserve the hydration within the epidermal tissue but also to protect our skin from environmental stressors and inhibit pathogen invasion ...
Haryung Park, Karina Arellano, Yuri Lee, Subin Yeo, Yosep Ji, Joontae Ko, Wilhelm Holzapfel   +6 more
doaj   +1 more source

A context‐dependent modulatory role for eIF6 in acquired resistance to vemurafenib in melanoma

FEBS Letters, EarlyView.
Acquired resistance to vemurafenib upregulates the translation factor eIF6 in melanoma cells. Silencing eIF6 in resistant cells reduces proliferation and partially restores drug sensitivity, whereas its overexpression increases sensitivity across melanoma lines regardless of BRAF status, via modulation of mTOR, S6K, and MAPK signaling.
George Kyriakopoulos, Antonia Petropoulou, Alexandra Anastogianni, Angelina Bania, Vassilis Stamatakis, Argyris Alexiou, Chi‐Ping Day, Glenn Merlino, Katerina Grafanaki, Constantinos Stathopoulos   +9 more
wiley   +1 more source

Itch Associated with Dryness of the Skin: the Pathophysiology and Influence of Moisturizers

, 2006
Mechanism . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 129 12.5 The Role of Moisturizers in Itch and Dry Skin . . . . . . . . . . . . .
Yosipovitch, Gil
core   +1 more source

Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer

Molecular Oncology, EarlyView.
Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola, Yasmine Illi, Anna Bircher, Marijn Wilmink, Rachele F. Malagutti, Solenn Ottié, Cordelia Schuler, Pedro A. Ruiz, Cheryl de Vallière, Klaus Seuwen, Gerhard Rogler, Martin Hausmann   +11 more
wiley   +1 more source

Dry Skin - Problems and Solutions [PDF]

, 2014
Dry skin (Ñ…erosis cutis) is a common problem a`ecting people art di`erent age and of di`erent skin types. he reasons for dry skin can be natural (physiological), pathological, or related to the inquence of unfavourable environmental factors.
Stancheva, Margarita; Medical university of Varna, Gesheva, Desislava; Medical university of Varna, Tubinis, Elena; Medical university of Varna, Bakardzhiev, Ilko; Medical university of Varna   +3 more
core   +1 more source

Comparison of the topical effect of Aloe vera and violet with hydroxyzine on dry skin of hemodialysis patients (A crossover interventional trial)

مجله دانشگاه علوم پزشکی بیرجند, 2022
Background and Aims: Dry skin is one of the most common skin complications associated with chronic renal failure in hemodialysis patients. Aloe vera gel and Violet oil can be effective in improving the symptoms of dryness through special mechanisms ...
Nima Rezaalizadeh, Anahita Arian, Kobra Naseri, Fatemeh Salmani, Ahmad Nasiri Furg   +4 more
doaj  

Dependence of Skin-Electrode Contact Impedance on Material and Skin Hydration

Sensors, 2022
Dry electrodes offer an accessible continuous acquisition of biopotential signals as part of current in-home monitoring systems but often face challenges of high-contact impedance that results in poor signal quality.
Krittika Goyal, David A. Borkholder, Steven W. Day   +2 more
doaj   +1 more source

Somatostatin receptor 4 (SSTR4) is a tumor suppressor in cutaneous and head & neck squamous cell carcinomas

Molecular Oncology, EarlyView.
This study identifies somatostatin receptor 4 (Sstr4) as a critical tumor suppressor against skin and head/neck cancers (HNSCC, cSCC, and BCC). The loss of Sstr4 removes a check on cell growth, causing hyperactivation of the MAPK‐ERK signaling pathway (↑).
Ali Taqvi, Tuan Khang Huynh, Adway Kadam, Zahra Kardan, Yue Yan, Amina Jamal Laham, Sampath Kumar Loganathan   +6 more
wiley   +1 more source

Regulation of the lncRNA NEAT1 by p53‐ΔNp63 crosstalk modulates the DNA damage response and therapeutic efficacy in HNSCC

Molecular Oncology, EarlyView.
In head and neck squamous cell carcinoma (HNSCC) p53 and p63 exert opposite roles on the transcription regulation of the lncRNA NEAT1. Under basal conditions, p53 levels are low and p63 represses NEAT1 expression. Upon genotoxic stress, p53 is rapidly induced, displacing p63 from the NEAT1 promoter leading to NEAT1 transcriptional activation and ...
Sara De Domenico, Veronica La Banca, Silvia D'Amico, Stefano Scalera, Sara Nicolai, Angelo Peschiaroli   +5 more
wiley   +1 more source

Recognizing and Managing Skin Integrity Issues in Compromised Aging Skin: The Importance of Gentle Skin Cleansing, Adequate Moisturization, and Skin Barrier Protection

Dermato
The skin serves as a primary defensive barrier to protect the body from environmental contaminants, infections and trauma. Unfortunately, skin barrier’s structural and functional integrity can be compromised, disrupted or impaired due to a combination of
Dalibor Mijaljica, Joshua P. Townley, Kira Torpy, Sharon Meere, Fabrizio Spada, Mikayla Lai   +5 more
doaj   +1 more source