Results 61 to 70 of about 11,781,139 (255)

Stimulator of interferon genes agonist augmented antitumor immunity of osimertinib in Egfr‐mutated lung cancer

Molecular Oncology, EarlyView.
Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura, Tadahiro Kuribayashi, Johannes Brägelmann, Sachi Okawa, Masataka Taoka, Shunta Mori, Tomoka Nishimura, Takaaki Tanaka, Go Makimoto, Kiichiro Ninomiya, Kammei Rai, Eiki Ichihara, Ryohei Katayama, Katsuyuki Hotta, Masahiro Tabata, Yosuke Togashi, Yoshinobu Maeda, Martin L. Sos, Katsuyuki Kiura, Kadoaki Ohashi   +19 more
wiley   +1 more source

Drying of Heat Sensitive Materials of High Moisture Content in Mechanically Spouted Bed of Inert Particles [PDF]

, 2008
In drying operation the material characteristics such as heat sensitivity, moisture content and particle size are of great importance, which should be taken into account in selection of proper design and conditions for the process.
Gyenis, János, Pallai-Varsányi, E., Tóth, J.   +2 more
core   +1 more source

The Influence of the Drying Process on the Dissolution Time of Concentrated Chinese Medicine Pills: Roles of Textural Properties and Water Migration

Pharmaceutics
Objectives: Concentrated pills, as a modernization and upgrade of traditional pills, have achieved significant advancements in dosage form. However, their extended disintegration and dispersion times have become a major limitation to their therapeutic ...
Xiaojun Wang, Qinmin Meng, Xiaojian Luo, Yao Zhang, Jing Yang, Xiaoyong Rao, Yingming Zhang, Haowei Lu, Yan He, Wei Liu   +9 more
doaj   +1 more source

Unidimensional Simulation of Drying Stress in Radiata Pine Wood

, 2015
This article reports an experimental and numeric methodology for studying the development of internal stresses during drying of solid wood. For validation purposes, tests were performed for drying of radiata pine at the equivalent of constant air-drying ...
Chavez, Cristian,, Salinas, Carlos T S,, Ananías, Rubén A.,, Elustondo, Diego,   +3 more
core   +1 more source

Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining

Molecular Oncology, EarlyView.
IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis, Jack V. Mills, Wojciech Niedzwiedz, Valentine M. Macaulay   +3 more
wiley   +1 more source

Effect of Different Drying Method on the Nutritional Quality and Antioxidant Activity of Jiangyong Fragrant Ginger Based on Principal Component Analysis

Shipin gongye ke-ji
To comprehensively evaluate the effects of drying methods on the nutritional quality and antioxidant activity of Jiangyong fragrant ginger, seven different drying methods including natural drying (ND), hot air drying (HAD), infrared drying (ID ...
Xinsheng XIAO, Wenjun ZHOU, Meitao FENG, Jialing LI, Liyan JIANG   +4 more
doaj   +1 more source

DRY METHODS OF DEALING WITH URING [PDF]

The American Journal of the Medical Sciences, 1895
n ...
openaire   +1 more source

Drying of paper : A review 2000–2018

, 2020
Drying of paper during 2000–2018 is reviewed. The review includes new drying processes, multi-cylinder dryers, tissue and impingement drying, TAD-drying, infrared drying and energy use for drying of paper.
Stenström, Stig, Stenström, Stig,, Lund University.   +2 more
core   +1 more source

MITF maintains genome stability in nonmelanocyte lineages

Molecular Oncology, EarlyView.
MITF is essential for melanocyte survival and acts as an oncogene in 10%–20% of melanomas. We show that MITF depletion causes genome instability in nonmelanocytic cells, leading to LATS2‐mediated P53 activation, cell cycle arrest, and apoptosis. This study highlights the role of MITF as a genome maintenance factor beyond the melanocyte lineage. Created
Drifa H. Gudmundsdottir, Adrián López García de Lomana, Thejus B. Venkatesh, Kritika Kirty, Snaevar Sigurdsson, Linda Vidarsdottir, Ramile Dilshat, Erla Sveinbjornsdottir, Snaedis Ragnarsdottir, Daniel H Magnusson, Maria R. Bustos, Eirikur Steingrimsson, Thorkell Gudjonsson, Stefan Sigurdsson   +13 more
wiley   +1 more source

Effect of Drying Method on Sulfur Dioxide Content in Edible Mushrooms and Endogenous Transformation Factors

Shipin gongye ke-ji
In this study, dietary risk assessment of sulfur dioxide content in both fresh and dried commercially available edible mushrooms (Tremella fuciformis, Lentinus edodes, and Agaricus blazei) was conducted through risk quotient and point assessment methods.
Yiming TIAN, Chun XU, Qiao YANG, Xinfang ZHANG, Songlin CHANG, Jiali REN   +5 more
doaj   +1 more source