Results 91 to 100 of about 11,498,745 (304)

Regulation of the lncRNA NEAT1 by p53‐ΔNp63 crosstalk modulates the DNA damage response and therapeutic efficacy in HNSCC

Molecular Oncology, EarlyView.
In head and neck squamous cell carcinoma (HNSCC) p53 and p63 exert opposite roles on the transcription regulation of the lncRNA NEAT1. Under basal conditions, p53 levels are low and p63 represses NEAT1 expression. Upon genotoxic stress, p53 is rapidly induced, displacing p63 from the NEAT1 promoter leading to NEAT1 transcriptional activation and ...
Sara De Domenico, Veronica La Banca, Silvia D'Amico, Stefano Scalera, Sara Nicolai, Angelo Peschiaroli   +5 more
wiley   +1 more source

Effects of Different Drying Methods on Nutritional Components, Antioxidant Activity and Volatile Components of Five Kinds of Dried Figs

Shipin gongye ke-ji
Drying methods may cause changes in the color and texture of figs, accelerating the loss of nutrients. In this study, five fig varieties ('Boji red' 'Orphan' 'Zhongzi' 'Qingpi' and 'Xinjiang Zaohuang') were used as research subjects.
Zhenzhen DING, Na XIA, Yanquan LIU, Tian ZHANG, Lei JIANG, Yanchang WANG, Chao ZHANG   +6 more
doaj   +1 more source

Drying characteristics of New Zealand Chestnuts [PDF]

, 2007
Chestnut is a relatively new nut crop to New Zealand and they do grow well in New Zealand conditions. Research to date in New Zealand indicated that New Zealand chestnuts present some unique features compared to chestnuts world wide.
Biju Cletus, Anila
core  

Extracellular matrix remodeling and immune reprogramming drive residual tumor progression of liver cancer after incomplete microwave ablation

Molecular Oncology, EarlyView.
Incomplete microwave ablation (iMWA) of liver cancer triggers a biphasic progression in residual tumors. At Day 3, the microenvironment is characterized by acute inflammatory responses and extracellular matrix (ECM) remodeling. By Day 14, a profound shift occurs toward oncogenic signal transduction and immunosuppression, marked by macrophage ...
Yu Liu, Yubei He, Nikolaus Berndt, Michael Mülleder, Kathrin Textoris‐Taube, Jing Guo, Matthias Stechele, Justus Ramtke, Shraga Nahum Goldberg, Lynn Jeanette Savic   +9 more
wiley   +1 more source

SPHINX31 acts as a SRPK1 inhibitor targeting the ATR/DNA‐PKcs/CHK1 replicative checkpoint to inhibit cell growth in non‐small cell lung cancer

Molecular Oncology, EarlyView.
The kinase SRPK1 directly interacts with the protein TOPBP1 and regulates the pre‐mRNA splicing of WIZ thereby contributing to the activation of the ATR/CHK1 replicative checkpoint in response to replicative stress. This allows cancer cells' genomic stability and survival.
Amani Shreim, Aurelie Genoux, Nadiia Zubchuk, Haoyang Zheng, Perla Salameh, Theo Ziegelmeyer, Fabien Dalonneau, Margot Rouchette, Christiane Oddou, Simona Miron, Helene Polveche, Adiilah Mamode Cassim, Carmen Garrido, Eleni Nikolakaki, Didier Auboeuf, Tao Jia, Sophie Zinn‐Justin, Beatrice Eymin   +17 more
wiley   +1 more source

Effects of different drying methods on drying characteristics and quality of taro strips

Shipin yu jixie
ObjectiveTo reduce postharvest spoilage of taro and improve the drying quality of taro strips.MethodsFour drying methods, i.e., vacuum microwave drying (VMD), hot air drying (HAD), heat pump drying (HPD), and far-infrared radiation drying (FIRD), were ...
LI Xiaoyun, XIE Ronghua, CHEN Sheng, HAN Chunyang, CHEN Junliang, REN Aiqing, DUAN Zhenhua   +6 more
doaj   +1 more source

Polarization‐resolved femtosecond Vis/IR spectroscopy tailored for resolving weak signals in biological samples using minimal sample volume

FEBS Open Bio, EarlyView.
Unique biological samples, such as site‐specific mutant proteins, are available only in limited quantities. Here, we present a polarization‐resolved transient infrared spectroscopy setup with referencing to improve signal‐to‐noise tailored towards tracing small signals. We provide an overview of characterizing the excitation conditions for polarization‐
Clark Zahn, Karsten Heyne
wiley   +1 more source

Optimization of sulfur-free color protection process and comparison of drying techniques for honeysuckle

Shipin yu jixie
ObjectiveTo develop green processing technology to inhibit the browning of fresh honeysuckle (Lonicera japonica Thunb) and enhance its drying quality.MethodsWith polyphenol oxidase relative enzyme activity and color difference values as evaluation ...
ZHAI Yumei, TANG Xiaojuan, FU Xiao, GONG Min, LIU Yunguo   +4 more
doaj   +1 more source

Single‐molecule DNA flow‐stretch assays for high‐throughput DNA–protein interaction studies

FEBS Open Bio, EarlyView.
We describe an optimised single‐molecule DNA flow‐stretch assay that visualises DNA–protein interactions in real time. Linear DNA fragments are tethered to a surface and stretched by buffer flow for fluorescence imaging. Using λ and φX174 DNA, this protocol enhances reproducibility and accessibility, providing a versatile approach for studying diverse ...
Ayush Kumar Ganguli, Mohammad Nour Alsamsam, Ugnė Bagdonaitė, Van Truc Vu, Chun‐Jen Huang, Polina Kuzhir, Mindaugas Zaremba, Aurimas Kopūstas, Marijonas Tutkus   +8 more
wiley   +1 more source

Effects of five drying methods on the drying characteristics and quality of peanuts

Shipin yu jixie
ObjectiveTo determine the appropriate mechanical drying technology for peanuts.MethodsFresh peanuts were used as raw materials. The effects of heat pump drying (HPD), far infrared drying (FID), electric heating drying (EHD), far infrared combined heat ...
XIE Yongkang, WANG Xi, JU Haoyu, WANG Weina, WANG Xiaodong   +4 more
doaj   +1 more source