Results 91 to 100 of about 11,781,139 (255)

A role for eIF5A in translational control of stress‐inducible proteins in multiple myeloma cell lines

Molecular Oncology, EarlyView.
Loss of eIF5A rewires thapsigargin‐mediated endoplasmic reticulum stress responses in multiple myeloma cells by selective translation of mRNA transcripts, consequently dampening thapsigargin‐induced unfolded protein response (UPR) activation and shifting the balance from induction of apoptosis toward cell survival and proliferation.
Demi Both, Ingrid A. M. Derks, Raphaël Vanleyssem, Marine Leclercq, Najla El Hachem, Pierre Close, Eric Eldering, Marco Vincent Haselager   +7 more
wiley   +1 more source

Modeling and Effects of Various Drying Methods on Sweet Potato Starch Properties

Walailak Journal of Science and Technology, 2011
Eleven mathematical models (Lewis, Page, Henderson and Pabis, modified Henderson and Pabis, Wang and Singh, logarithmic, two term, two term exponential, Midilli, approximation of diffusion and Verma et al, model) were used for describing the drying ...
Ho Minh THAO, Athapol NOOMHORM
doaj   +1 more source

Regulation of the lncRNA NEAT1 by p53‐ΔNp63 crosstalk modulates the DNA damage response and therapeutic efficacy in HNSCC

Molecular Oncology, EarlyView.
In head and neck squamous cell carcinoma (HNSCC) p53 and p63 exert opposite roles on the transcription regulation of the lncRNA NEAT1. Under basal conditions, p53 levels are low and p63 represses NEAT1 expression. Upon genotoxic stress, p53 is rapidly induced, displacing p63 from the NEAT1 promoter leading to NEAT1 transcriptional activation and ...
Sara De Domenico, Veronica La Banca, Silvia D'Amico, Stefano Scalera, Sara Nicolai, Angelo Peschiaroli   +5 more
wiley   +1 more source

Effect of Extraction Solvents and Drying Methods on the Physicochemical and Antioxidant Properties of Helicteres hirsuta Lour. Leaves

Technologies, 2015
Helicteres hirsuta Lour. (H. hirsuta L.) is widely distributed in southeast Asian countries and has been used traditionally as a medicinal plant. However, optimal conditions for preparation of dried materials for further processing and suitable solvents ...
Hong Ngoc Thuy Pham, Van Tang Nguyen, Quan Van Vuong, Michael C. Bowyer, Christopher J. Scarlett   +4 more
doaj   +1 more source

A Review on Thin-Layer Drying-Curve Equations

, 2014
KILIC, Aydin/0000-0002-8952-9909This paper presents a comprehensive review of thin-layer drying-curve models available in the literature and their comparisons for single-layer drying applications from 2003 to 2013.
Aydin Kilic, Küçük, Haydar, Midilli, Adnan, Kılıç, Aydın, Dinçer, İbrahim, KILIÇ, AYDIN, Ibrahim Dincer, Adnan Midilli, Haydar Kucuk   +8 more
core   +1 more source

Extracellular matrix remodeling and immune reprogramming drive residual tumor progression of liver cancer after incomplete microwave ablation

Molecular Oncology, EarlyView.
Incomplete microwave ablation (iMWA) of liver cancer triggers a biphasic progression in residual tumors. At Day 3, the microenvironment is characterized by acute inflammatory responses and extracellular matrix (ECM) remodeling. By Day 14, a profound shift occurs toward oncogenic signal transduction and immunosuppression, marked by macrophage ...
Yu Liu, Yubei He, Nikolaus Berndt, Michael Mülleder, Kathrin Textoris‐Taube, Jing Guo, Matthias Stechele, Justus Ramtke, Shraga Nahum Goldberg, Lynn Jeanette Savic   +9 more
wiley   +1 more source

Effects of Different Drying Methods on Nutritional Components, Antioxidant Activity and Volatile Components of Five Kinds of Dried Figs

Shipin gongye ke-ji
Drying methods may cause changes in the color and texture of figs, accelerating the loss of nutrients. In this study, five fig varieties ('Boji red' 'Orphan' 'Zhongzi' 'Qingpi' and 'Xinjiang Zaohuang') were used as research subjects.
Zhenzhen DING, Na XIA, Yanquan LIU, Tian ZHANG, Lei JIANG, Yanchang WANG, Chao ZHANG   +6 more
doaj   +1 more source

Numerical simulation of drying of Pinus pseudostrobus wood with Comsol Multiphysics [PDF]

, 2011
In this work, we present the second part of our investigation. In the first part, we have published a semi-empirical model for drying. In this second part, we present the numerical solution of a drying model for Pinus pseudostrobus (Mexican softwood ...
HERNANDEZ-BAUTISTA, Emilio, SANDOVAL-TORRES, Sadoth, Hernández-Bautista, E., Rodríguez-Ramírez, J., Nadeou, J. P., MÉNDEZ-LAGUNAS, Lilia Leticia, NADEAU, Jean-Pierre, HERNANDEZ-BAUTISTA, , E, RODRÍGUEZ-RAMÍREZ, Juan, Méndez-Lagunas, L., SANDOVAL-TORRES, S., RODRÍGUEZ-RAMÍREZ, , J.   +11 more
core  

SPHINX31 acts as a SRPK1 inhibitor targeting the ATR/DNA‐PKcs/CHK1 replicative checkpoint to inhibit cell growth in non‐small cell lung cancer

Molecular Oncology, EarlyView.
The kinase SRPK1 directly interacts with the protein TOPBP1 and regulates the pre‐mRNA splicing of WIZ thereby contributing to the activation of the ATR/CHK1 replicative checkpoint in response to replicative stress. This allows cancer cells' genomic stability and survival.
Amani Shreim, Aurelie Genoux, Nadiia Zubchuk, Haoyang Zheng, Perla Salameh, Theo Ziegelmeyer, Fabien Dalonneau, Margot Rouchette, Christiane Oddou, Simona Miron, Helene Polveche, Adiilah Mamode Cassim, Carmen Garrido, Eleni Nikolakaki, Didier Auboeuf, Tao Jia, Sophie Zinn‐Justin, Beatrice Eymin   +17 more
wiley   +1 more source

Targeting the EpCAM‐AXL axis to overcome drug resistance in lung cancer

Molecular Oncology, EarlyView.
Lung cancer cells often evade therapy by hijacking signaling pathways. We reveal that cleaved EpCAM (sEpCAM) stabilizes the oncogenic protein AXL, driving NF‐κB and STAT3‐mediated chemoresistance. This EpCAM‐AXL axis identifies a high‐risk patient subset with poor prognosis.
Alexa Guerrero‐Alba, Mark Shacker, Timothy P. Fleming, Michael A. Smith, Ross M. Bremner, Narendra V. Sankpal   +5 more
wiley   +1 more source