Results 61 to 70 of about 915,224 (315)

pH‐mediated activation of the lysosomal arginine sensor SLC38A9

FEBS Letters, EarlyView.
Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley   +1 more source

Influence of Cooking and Drying Methods on Quality Characteristics of Different Cereals Bulgur [PDF]

Food Technology Research Journal
This study aimed to develop functional whole-grain bulgur alternatives to wheat bulgur and evaluate their quality characteristics. Bulgur produced from durum wheat, barley, sorghum, triticale, oat, and millet were investigated. The current study assessed
Asmaa M. Marie, Seham Y. Gebreil
doaj   +1 more source

Volatile Composition and Sensory Properties as Quality Attributes of Fresh and Dried Hemp Flowers (Cannabis sativa L.)

Foods, 2020
Flowers of hemp (Cannabis sativa L.) are widely used in cosmetics, food, and in the pharmaceutical industry. The drying process plays a key role in retention of aroma and also in the quality of products.
Andrzej Kwaśnica, Natalia Pachura, Klaudia Masztalerz, Adam Figiel, Aleksandra Zimmer, Robert Kupczyński, Katarzyna Wujcikowska, Angel A. Carbonell-Barrachina, Antoni Szumny, Henryk Różański   +9 more
doaj   +1 more source

Betalain extracts: Drying techniques, encapsulation, and application in food industry

Food Frontiers, 2023
One of the important food additives used in the food industry is betalain, which is applied as a natural dye. Red beet is the most common resource of betalain. To increase its shelf life, encapsulation followed by drying is commonly carried out. However,
Dian Shofinita, Mifta Fawwaz, Amarthya Benigna Achmadi   +2 more
doaj   +1 more source

Influence of different drying parameters on the composition of volatile compounds of thyme and rosemary cultivated in Sardinia [PDF]

, 2007
The shelf life of spices is traditionally extended by drying. Fresh herbs, due to their high water content, undergo microorganism growth and adverse biochemical reactions. On the other hand drying may result in a lot of physical and chemical alterations.
Del Caro, Alessandra, Foddai, Marzia, Marchetti, Mauro, Meier, Peter, Onorati, Vincenzo, Piga, Antonio <1965- >, Usai, Marianna, Vinci, Francesco   +7 more
core  

Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin

Molecular Oncology, EarlyView.
The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla, Jan Kosla, Magdalena Prechova, Lukas Frick, Patricia Bortel, Yasmin Borutzki, Andrea Bileck, Christopher Gerner, Samuel M. Meier‐Menches, Selma Osmanagic‐Myers, Martin Gregor   +10 more
wiley   +1 more source

Development of coal-feeding systems at the Morgantown Energy Research Center [PDF]

, 1977
Systems for feeding crushed and pulverized coal into coal conversion reactor vessels are described. Pneumatic methods for feeding pulverized coal, slurry feeders, and coal pumps, methods for steam pickup, and a method for drying a water-coal slurry in a ...
Hobday, J. M.
core   +1 more source

Genetic attenuation of ALDH1A1 increases metastatic potential and aggressiveness in colorectal cancer

Molecular Oncology, EarlyView.
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova, Zuzana Kozovska, Ondrej Pos, Kristina Pavlov, Sachin Gulati, Peter Makovicky, Kristina Jakic, Monika Burikova, Eva Sedlackova, Barbora Svitkova, Silvia Tyciakova, Vojtech Bystry, Nicolas Blavet, Boris Tichy, Matej Hrnciar, Jaroslav Budis, Miroslav Tomas, Peter Dubovan, Georgina Kolnikova, Veronika Repaska, Nikoleta Mojzesova, Eva Zomborska, Daniel Pindak, Michal Mego, Tomas Szemes, Miroslava Matuskova   +25 more
wiley   +1 more source

Quality of dry ginger (Zingiber officinale) by different drying methods [PDF]

Journal of Food Science and Technology, 2012
Ginger rhizomes sliced to various lengths of 5, 10, 15, 20, 30, 40, 50 mm and whole rhizomes were dried from an initial moisture content of 81.3 % to final moisture content of less than 10 % by various drying methods like sun drying, solar tunnel drying and cabinet tray drying at temperatures of 50, 55, 60 and 65 °C.
Jayashree, E, Visvanathan, R, John Zachariah, T   +2 more
openaire   +2 more sources

Dimethyl fumarate combined with cisplatin at subcytotoxic doses sensitizes cervical cancer toward ferroptosis and apoptosis through GSH restriction and p53 (re)activation

Molecular Oncology, EarlyView.
Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano, Giuseppina Minopoli, Simona Romano, Laura Marrone, Katia Aquilano, Maria Lina Tornesello, Raffaella Faraonio   +6 more
wiley   +1 more source