Results 101 to 110 of about 10,333,968 (356)

Pre‐analytical optimization of cell‐free DNA and extracellular vesicle‐derived DNA for mutation detection in liquid biopsies

open access: yesMolecular Oncology, EarlyView.
Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen   +11 more
wiley   +1 more source

Preliminary study of drying of natural coffee by cyclical pressure changes

open access: yesDyna, 2020
A “special coffee” is obtained with an adequate drying process, which allows the preservation of volatile substances responsible for excellent cup quality.
Alfonso Parra-Coronado   +5 more
doaj   +1 more source

Communal residential laundry washing and drying : can it provide demand-side electrical load flexibility? [PDF]

open access: yes, 2011
Changes in lifestyle have led to increased use and ownership rates of domestic appliances resulting in increasing electrical consumption in the residential sector. An important element of this consumption is due to domestic washing and drying of laundry.
Borg, Simon Paul   +5 more
core  

Shrinkage and Other Corn-Quality Changes From Drying at Commercial Elevators [PDF]

open access: yes, 1984
Weight losses and corn-quality changes from drying and handling were measured at two modern country elevators. In addition to moisture losses, material handing losses averaged 0.88% of initial weight, with a range of 0.64% to 1.33% of initial weight ...
Hurburgh, Charles   +2 more
core   +3 more sources

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

open access: yesMolecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla   +9 more
wiley   +1 more source

Performance Evaluation of a Solar-Assisted Multistage Heat Pump Drying System Based on the Optimal Drying Conditions for Solanum lycopersicum L.

open access: yesFoods
This study aims to evaluate the drying performance of a multi-stage solar-assisted heat pump drying system for tomatoes. The method involves theoretical calculations based on the optimal drying process and experimental investigations to assess the impact
Yimin Tang   +7 more
doaj   +1 more source

Cell‐cycle‐specific lesion evolution rather than inhibition of double‐strand‐break repair underpins cisplatin radiosensitization

open access: yesMolecular Oncology, EarlyView.
We analyze cisplatin–DNA adducts (CDAs) and double‐strand breaks (DSBs) in a cell‐cycle‐dependent manner. We find that CDAs form similarly across all cell cycle phases. DSBs arise only in S‐phase. CDAs might not directly impair DSB repair, but S‐phase DSB lesions evolve in the presence of CDAs and disrupt repair in G2, also causing radiosensitization ...
Ye Qiu   +10 more
wiley   +1 more source

Design and optimization of heat pump with infrared drying for Glycyrrhiza uralensis (Licorice) processing

open access: yesFrontiers in Nutrition
A new dryer, integrating infrared and heat pump drying technologies, was designed to enhance licorice processing standardization, aiming at improved drying efficiency and product quality.
Lichun Zhu   +12 more
doaj   +1 more source

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