Results 41 to 50 of about 788,101 (310)

Cell wall target fragment discovery using a low‐cost, minimal fragment library

FEBS Letters, EarlyView.
LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan, Mathew Stanley, Olawale Raimi, Andrew T. Ferenbach, Helge C Dorfmueller, Daan M. F. van Aalten   +5 more
wiley   +1 more source

Performance evaluation of a flatbed maize dryer with a biomass heat source

International Journal of Agricultural Research, Innovation and Technology, 2021
The technical performance of a 3-tonne capacity flatbed grain dryer was assessed based on its drying rate and drying efficiency. In addition, the quality of maize grains dried in the drying system was investigated through stress-crack analysis and ...
JO Akowuah, HA Boateng, G Obeng Akrofi, DE Maier   +3 more
doaj   +1 more source

Desiccation of a clay film: Cracking versus peeling

, 2008
Cracking and peeling of a layer of clay on desiccation has been simulated using a spring model. A vertical section through the layer with finite thickness is represented by a rectangular array of nodes connected by linear springs on a square lattice. The
Blaudeck, Peter, Dutta, Tapati, Hoffmann, K. H., Prehl, Janett, Sadhukhan, Supti, Tarafdar, Sujata   +5 more
core   +1 more source

Drying-Rate Limit in Condenser Drying of Thin Film Coatings

JOURNAL OF CHEMICAL ENGINEERING OF JAPAN, 2006
Two different drying regimes were observed in air-free condenser drying of solvent-polymer solution coatings. The measured solvent drying rate for the constant rate period increases with an increasing solvent partial pressure gradient in the low pressure gradient regime.
Masato Yamamura, Takayuki Inoue, Yoshihide Mawatari, Hiroyuki Kage   +3 more
openaire   +1 more source

Inhibiting stearoyl‐CoA desaturase suppresses bone metastatic prostate cancer by modulating cellular stress, mTOR signaling, and DNA damage response

FEBS Letters, EarlyView.
Bone metastasis in prostate cancer (PCa) patients is a clinical hurdle due to the poor understanding of the supportive bone microenvironment. Here, we identify stearoyl‐CoA desaturase (SCD) as a tumor‐promoting enzyme and potential therapeutic target in bone metastatic PCa.
Alexis Wilson, Mackenzie K Herroon, Shane Mecca, Laimar C Garmo, Jacob Lindquist, Shrila Rajendran, Steve M. Patrick, Izabela Podgorski   +7 more
wiley   +1 more source

Drying Characteristics and Kinetics of Electrohydrodynamics-Heat Pump of Banana Slices

Shipin gongye ke-ji, 2022
This paper experimentally studied the effects of different factors of electrohydrodynamics-heat pump combined drying on the drying characteristics of banana slices.
Yiman WANG, Yin LIU, Zhaofeng MENG, Chenyang DU, Rusheng HU, Xiangna CUI, Hang WANG   +6 more
doaj   +1 more source

Mechanical tuning of the evaporation rate of liquid on crossed fibers

, 2015
We investigate experimentally the drying of a small volume of perfectly wetting liquid on two crossed fibers. We characterize the drying dynamics for the three liquid morphologies that are encountered in this geometry: drop, column and a mixed morphology,
Alban Sauret, Anantharaju N., Andreas E., Beatrice Soh, Berteloot G., Borzsonyi T., Boulogne F., Boulogne F., Cachile M., Carroll B. J., Cazabat A.-M., Clement F., Duprat C., Duprat C., Emilie Dressaire, François Boulogne, Gelderblom H., Guéna G., Guéna G., Howard A. Stone, Langmuir I., Lopes M., Lorenceau E., Maxwell J. C., Maxwell J. C., McHale G., McHale G., Pham C.-T., Plawsky J. L., Poulard C., Princen H. M., Protiere S., Quéré D., Quéré D., Quéré D., Rayleigh L., Reyssat M., Sauret A., Shantz H. L., Sultan E., Wayner P. C.   +40 more
core   +4 more sources

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

FEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee, Dimitrios Bekiari, Sofia Doello, Karl Forchhammer   +3 more
wiley   +1 more source

Nicotinamide N‐methyltransferase promotes drug resistance in lung cancer, as revealed by nascent proteomic profiling

Molecular Oncology, EarlyView.
AZD9291 has shown promise in targeted cancer therapy but is limited by resistance. In this study, we employed metabolic labeling and LC–MS/MS to profile time‐resolved nascent protein perturbations, allowing dynamic tracking of drug‐responsive proteins. We demonstrated that increased NNMT expression is associated with drug resistance, highlighting NNMT ...
Zhanwu Hou, Zhen Wang, Fei Yang, Xiao Han, Lei Li, Huadong Liu   +5 more
wiley   +1 more source

The Effect of Weather on Air-Drying of Messassa Wood

Floresta e Ambiente
This study intended to assess the effect of weather on the air-drying process of messassa wood (Brachystegia spiciformis Benth) in two areas of Mozambique (Machipanda and Beira city). First, the logs were sawn into 27 mm thick boards. Every five days the
Andrade Fernando Egas, Ricardo Jorge Klitzke, Reinaldo Calçada Guina Luis, Ernesto Uetimane Junior, Djeison Cesar Batista, Márcio Pereira da Rocha   +5 more
doaj   +1 more source