Results 101 to 110 of about 412,965 (302)

Systemic dysregulation of apolipoproteins in amyotrophic lateral sclerosis serum

FEBS Open Bio, EarlyView.
Amyotrophic lateral sclerosis (ALS) is a fatal disease that damages motor neurons. This study found that people with ALS show significant changes in blood fats and the proteins that carry them. Several apolipoproteins were higher, lipid balances were altered, and normal protein–lipid relationships were disrupted.
Finula I. Isik, Russell Pickford, Hannah C. Timmins, Olivier Piguet, Glenda M. Halliday, Matthew C. Kiernan, Woojin Scott Kim   +6 more
wiley   +1 more source

Effects of temporal salt accumulation during accelerated drying-wetting cycles on physical properties of cement mortars and determining of ocean salt crystallization pressure stress

Next Materials
Elucidating the degradation mechanism of inorganic materials in special service environments such as ocean environment has important scientific and engineering significance.
Jinbo Yang, Ze Zhang, Yu Zhang
doaj   +1 more source

Correlating fissure occurrence to rice quality for various drying and tempering treatments [PDF]

, 2001
When a rice kernel fissures, it can break in subsequent food processing operations and lose its commercial value. Head rice yield (HRY) is a measure of the percent of kernels that remain whole (at least three-fourths of original length) after rice has ...
Cnossen, A. G., Jimenez, Monica J., Siebenmorgen, Terry J.   +2 more
core   +2 more sources

The Effect of Fatigue and Stress on Dry eye

The Korean Journal of Vision Science, 2017
Purpose: This study was performed to investigate the relationship between dry eye by fatigue and stress. Methods: Using the survey data aimed at a total of 365 adults aged 19 and over, the subjects’ sociodemographic variables, Fatigue Severity Scale, Stress Scale, and Ocular Surface Disease Index were applied in a self-administering way, and the cross ...
Hye-Won Park, Tae-Hun Kim
openaire   +1 more source

Large‐scale bidirectional arrayed genetic screens identify OXR1 and EMC4 as modifiers of αSynuclein aggregation

FEBS Open Bio, EarlyView.
Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane, Lea Nikolić, Lorenzo Maraio, Thomas Goiran, Nathan Karpilovsky, Stefano Sellitto, Vangelis Bouris, Jiang‐An Yin, Ronald Melki, Edward A Fon, Adriano Aguzzi, Elena De Cecco   +11 more
wiley   +1 more source

Control of Internal Moisture Transfer Direction and Lateral Moisturization to Mitigate Drying Defects in Large-Cross Section Timber

BioResources
Methods for surface moisturization and control of internal moisture movement have been developed to minimize moisture gradients and reduce drying defects, such as cracks, in large cross-sectional timbers used for restoring palaces, temples, and cultural ...
Bat-Uchral Batjargal, Taekyeong Lee, Chang-Jin Lee, Jung-Kwon Oh, Hwanmyeong Yeo   +4 more
doaj  

Mass spectrometry based identification of AMP‐O‐Tris generated by Thermococcus onnurineus Cas10

FEBS Open Bio, EarlyView.
Isolated Thermococcus onnurineus Cas10 generates the noncanonical ATP‐derived product AMP‐O‐Tris while in Tris‐containing buffer as identified via mass spectrometry, revealing relaxed nucleophile selectivity under isolated conditions. These findings suggest that multiprotein Csm complex assembly restricts Cas10 reactivity toward canonical cyclic ...
Su‐Jin Lee, Ga Seul Lee, JinHan Kim, Kwang‐Hyun Park, Seong‐Ryung Go, Jeong Hee Moon, Eui‐Jeon Woo   +6 more
wiley   +1 more source

Computer Simulation of Drying Stresses in Wood

Journal of the Society of Materials Science, Japan, 1973
Computer simulation was conducted to assess the effect of the rate of drying on stress in wood during drying. Numerical calculations for the simulation were carried out with an electronic computer FACOM 270-20/30. Examples of the flow chart and FORTRAN programs used are shown in the text where we assumed that the stress follows the integro-differential
openaire   +2 more sources

Long‐term hippocampal alterations and cognitive impairment in a murine model of surgical sepsis

FEBS Open Bio, EarlyView.
Using a mouse model of surgical sepsis, we tested long‐term memory and analyzed the transcriptome of single cells isolated from the hippocampus. Survivor mice showed worse memory, loss of certain brain cell subpopulations, and abnormal immune cell activity—suggesting that post‐sepsis brain alterations may be linked to cognitive deficits.
Dong Seong Cho, Rebecca Schmitt, Aneesha Dasgupta, Alexandra Ducharme, Jason Doles   +4 more
wiley   +1 more source

Derivation and characterization of retinal pigment epithelium from urine‐derived iPSCs

FEBS Open Bio, EarlyView.
Age‐related macular degeneration causes vision loss via RPE dysfunction and loss. Traditional iPSC therapies rely on invasive biopsies, limiting scalability. Here, we utilize urine‐derived stem cells as an accessible source to generate u‐iPSCs, successfully differentiated into pigmented RPE. This “Urine‐to‐Retina” platform provides a promising path for
Daniella Beiner, Hainan Zhu, Carol Christine Bosholm, Heuy‐Ching Wang, Tracy Criswell, Anthony Atala, Jian‐Xing Ma, Yuanyuan Zhang   +7 more
wiley   +1 more source