Results 41 to 50 of about 412,965 (302)

Cell wall target fragment discovery using a low‐cost, minimal fragment library

open access: yesFEBS Letters, EarlyView.
LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan   +5 more
wiley   +1 more source

Combined Soil Physical Stress of Soil Drying, Anaerobiosis and Mechanical Impedance to Seedling Root Growth of Four Crop Species

open access: yesPlant Production Science, 2007
Soil compaction often creates combined physical stresses of drought, anaerobiosis, and mechanical impedance in field soil. This paper aims to analyze the effect of combined and independent soil physical stresses on crop root growth to find out the ...
Morio Iijima   +2 more
doaj   +1 more source

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

open access: yesFEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee   +3 more
wiley   +1 more source

Effect of Wetting-Drying Cycle on the Deformation and Seepage Behaviors of Rock Masses around a Tunnel

open access: yesGeofluids, 2020
Water inrush caused by the wetting-drying cycle is a difficult problem in tunnel excavation. To investigate the effect of the wetting-drying cycle on the stability of the tunnel surrounding rock, physical experiments and numerical simulations regarding ...
Qingzhen Guo   +3 more
doaj   +1 more source

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

open access: yesFEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Tau acetylation at K331 has limited impact on tau pathology in vivo

open access: yesFEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto   +3 more
wiley   +1 more source

DRYING STRATEGIES CAPABLE OF REDUCING THE STRESS LEVEL OF A STACK OF BOARDS AS DEFINED BY A COMPREHENSIVE DUAL SCALE MODEL

open access: yesMaderas: Ciencia y Tecnología, 2008
During drying, stresses and deformations develop in a wood board due to shrinkage fields which result from moisture content and temperature field variations.
Romain Rémond, Patrick Perré
doaj  

Simulation and Experimental Studies of Heat-Mass Transfer and Stress–Strain in Carrots During Hot Air Drying

open access: yesAgriculture
Models were developed to study the heat-mass transfer and stress–strain process in carrots during hot air drying. The distribution and variation in temperature, moisture content, strain, and stress of the samples were investigated at different drying ...
Yanyan Li   +5 more
doaj   +1 more source

2D model simulating the hydro-rheological behavior of leather during convective drying

open access: yesComptes Rendus. Mécanique, 2021
An experimental and numerical study of a two-dimensional spatio-temporal variation of the temperature, moisture content, and mechanical stress during the convective drying process of unsaturated and deformable products (leather) were conducted.
Benmakhlouf, Naima   +3 more
doaj   +1 more source

Home - About - Disclaimer - Privacy