Results 41 to 50 of about 131,234 (264)

Stress characteristics and stress reversal mechanism of white birch (Betula platyphylla) disks under different drying conditions

Maderas: Ciencia y Tecnología, 2016
Drying stress is the main cause for the generation of drying cracks in wood disks during drying, which limits the processing and utilization of this valuable material.
Zongying Fu, Jingyao Zhao, Yangyi Lv, Siqi Huan, Yingchun Cai   +4 more
doaj  

Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization

Molecular Oncology, EarlyView.
In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu, Nicolas J. Niklaus, Anna M. Schläfli, Igor Tokarchuk, Magali Humbert, Federico La Manna, Bich Vu, David Maul, Ramin Radpour, Marianna Kruithof‐de Julio, Inti Zlobec, Jörn Dengjel, Bruce E. Torbett, Mario P. Tschan   +13 more
wiley   +1 more source

Investigation of oscillating climates for wood drying using the flying wood test and loaded beams: Need for a new mechano-sorptive model

Maderas: Ciencia y Tecnología, 2014
In this work, the effects of moisture content variations produced by oscillating drying conditions have been studied by means of non-symmetrical drying (flying wood) and loaded drying (3-point bending test).
Romain Rémond, Mariella De La Cruz, Daniel Aléon, Patrick Perré   +3 more
doaj  

PAK1 activation drives divergent resistance mechanisms to aromatase inhibition and tamoxifen in a luminal: A breast cancer model

Molecular Oncology, EarlyView.
Breast cancer remains a major cause of cancer death in women, frequently developing endocrine therapy resistance. This study demonstrates that upregulated p21‐activated kinase 1 (PAK1) activity drives resistance to tamoxifen and long‐term estrogen deprivation in ER+ breast cancer models.
Luisa Schwarzmüller, Janina Müller, Efstathios‐Iason Vlachavas, Lukas Beumers, Lena Fleischhacker, Sara Burmester, Angelika Wörner, Sabine Karolus, Dominic Helm, Cindy Körner, Stefan Wiemann   +10 more
wiley   +1 more source

Drying strategies capable of reducing the stress level of a stack of boards as defined by a comprehensive dual scale model

Maderas: Ciencia y Tecnología, 2014
During drying, stresses and deformations develop in a wood board due to shrinkage fields which result from moisture content and temperature field variations.
Romain Rémond, Patrick Perré
doaj  

Optimization of heat shock, acid shock and salt stress process and its mechanism of protection before spray drying of Baijiu yeast - Modified sporidiobolus Johnsonii A

Bioresources and Bioprocessing
The low survival rate of high-quality baijiu yeast, Modified Sporidiobolus Johnsonii A (MSJA), during spray drying and the unclear mechanisms underlying its stress treatment processes (heat shock, acid shock, and salt stress) have significantly hindered ...
Fengkui Xiong, Zhongbin Liu, Jingyu Li, Guangzhong Hu, Duqing Qu, Bo Huang   +5 more
doaj   +1 more source

Macro-micro tests of cohesive soil under varied normal and shear stresses subjected to drying-wetting cycles

Journal of Rock Mechanics and Geotechnical Engineering
The mechanical behavior of cohesive soil is sensitized to drying-wetting cycles under confinements. However, the hydromechanical coupling effect has not been considered in current constitutive models.
Fangyue Luo, Ga Zhang, Yangping Yao
doaj   +1 more source

CEACAM1 participation in breast cancer progression

Molecular Oncology, EarlyView.
In invasive breast cancer (BC), CEACAM1 shifts from an apical to a uniform membranous/cytoplasmic pattern, or is lost, as tumors dedifferentiate, inversely tracking the Ki‐67 proliferative index. In MCF‐7 cells, only CEACAM1‐4L suppresses proliferation, repressing cell cycle and growth factor genes.
Mykola Lyndin, Irina Kube‐Golovin, Anatolii Romaniuk, Gunther Wennemuth   +3 more
wiley   +1 more source

Pharmacological chromatin remodeling enhances response to estrogen therapy in ER+ breast cancer

Molecular Oncology, EarlyView.
Estrogen therapy elicits clinical benefit in ~ 30% of patients with endocrine‐resistant estrogen receptor (ER)‐positive breast cancer. Based on findings that ER transcriptional activation underlies response to estrogen therapy, we tested the effects of epigenetic dysregulation via pharmacological inhibition of histone deacetylases (HDACi).
Anneka L. Johnson Thomas, Barbara Karakyriakou, Patricia C. Muskus, Alyssa M. Roberts, Justin Rendleman, Alexa Warren, Hanxu Lu, Kimberly A. Birmingham, Malone K. Friedman, Abigail E. Goen, Huijuan Yang, Owen M. Wilkins, Fred W. Kolling, Eugene Demidenko, Julie M. Jorns, Brock C. Christensen, Todd W. Miller   +16 more
wiley   +1 more source

EFFECTS OF SAWING PATTERN ON DRYING RATE AND RESIDUAL DRYING STRESSES OF PINUS RADIATA LUMBER

Maderas: Ciencia y Tecnología, 2002
Flatsawn and quartersawn Pinus radiata (radiata pine) sapwood boards were dried in a tunnel dryer in three runs using three drying schedules. These schedules represented low temperature (LT), accelerated conventional temperature (ACT) and high ...
S Pang, A.N Haslett
doaj