Results 41 to 50 of about 3,047,303 (249)

Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry

FEBS Letters, EarlyView.
EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri, Ayaka Nagasato‐Ichikawa, Keita Iida, Shuhei Kimura, Akira Imamoto, Mariko Okada   +5 more
wiley   +1 more source

Simulation and Experimental Studies of Heat-Mass Transfer and Stress–Strain in Carrots During Hot Air Drying

Agriculture
Models were developed to study the heat-mass transfer and stress–strain process in carrots during hot air drying. The distribution and variation in temperature, moisture content, strain, and stress of the samples were investigated at different drying ...
Yanyan Li, Mingxia Liang, Jinyan Li, Keyi Jiang, Xiyang Li, Zhaohui Zheng   +5 more
doaj   +1 more source

Effect of Wetting-Drying Cycle on the Deformation and Seepage Behaviors of Rock Masses around a Tunnel

Geofluids, 2020
Water inrush caused by the wetting-drying cycle is a difficult problem in tunnel excavation. To investigate the effect of the wetting-drying cycle on the stability of the tunnel surrounding rock, physical experiments and numerical simulations regarding ...
Qingzhen Guo, Haijian Su, Hongwen Jing, Wenxin Zhu   +3 more
doaj   +1 more source

Functional comparison of EncB and EncC cargo proteins in iron storage within the Myxococcus xanthus encapsulin

FEBS Letters, EarlyView.
Encapsulins are protein nanocompartments that play an important role in iron storage. In the Myxococcus xanthus encapsulin system, two cargo proteins called EncB and EncC contribute to iron mineralization. Here, we show that EncB and EncC generate iron‐containing minerals with distinct chemical compositions, suggesting that the composition of stored ...
Harry B. McDowell, Thomas Walther, Egbert Hoiczyk   +2 more
wiley   +1 more source

Stress characteristics and stress reversal mechanism of white birch (Betula platyphylla) disks under different drying conditions

Maderas: Ciencia y Tecnología, 2016
Drying stress is the main cause for the generation of drying cracks in wood disks during drying, which limits the processing and utilization of this valuable material.
Zongying Fu, Jingyao Zhao, Yangyi Lv, Siqi Huan, Yingchun Cai   +4 more
doaj  

Leucine‐rich glioma inactivated 1 (LGI1) is a ganglioside‐binding protein

FEBS Letters, EarlyView.
Neuronal hyperexcitability associated with a decrease/absence of the extracellular protein LGI1 has been suggested to be primarily due to the downregulation of Kv1 channel expression. The molecular mechanisms underlying this decrease have not yet been elucidated.
Kévin Debreux, Christian Lévêque, Fodil Azzaz, Marion Sangiardi, Sarosh R Irani, Michael Seagar, Jacques Fantini, Oussama El Far   +7 more
wiley   +1 more source

Investigation of oscillating climates for wood drying using the flying wood test and loaded beams: Need for a new mechano-sorptive model

Maderas: Ciencia y Tecnología, 2014
In this work, the effects of moisture content variations produced by oscillating drying conditions have been studied by means of non-symmetrical drying (flying wood) and loaded drying (3-point bending test).
Romain Rémond, Mariella De La Cruz, Daniel Aléon, Patrick Perré   +3 more
doaj  

A context‐dependent modulatory role for eIF6 in acquired resistance to vemurafenib in melanoma

FEBS Letters, EarlyView.
Acquired resistance to vemurafenib upregulates the translation factor eIF6 in melanoma cells. Silencing eIF6 in resistant cells reduces proliferation and partially restores drug sensitivity, whereas its overexpression increases sensitivity across melanoma lines regardless of BRAF status, via modulation of mTOR, S6K, and MAPK signaling.
George Kyriakopoulos, Antonia Petropoulou, Alexandra Anastogianni, Angelina Bania, Vassilis Stamatakis, Argyris Alexiou, Chi‐Ping Day, Glenn Merlino, Katerina Grafanaki, Constantinos Stathopoulos   +9 more
wiley   +1 more source

Contact drying of particulate pharmaceuticals: modelling and simulation [PDF]

, 2010
In order to give a concrete response to the need of predictive contact drying simulation tools in pharmaceutical industry, simulation programs for contact drying of pharmaceutical powders were developed in this thesis work.
Intelvi, Marco
core  

DRYING STRATEGIES CAPABLE OF REDUCING THE STRESS LEVEL OF A STACK OF BOARDS AS DEFINED BY A COMPREHENSIVE DUAL SCALE MODEL

Maderas: Ciencia y Tecnología, 2008
During drying, stresses and deformations develop in a wood board due to shrinkage fields which result from moisture content and temperature field variations.
Romain Rémond, Patrick Perré
doaj