Results 61 to 70 of about 1,767 (181)

Selinexor and Venetoclax Combination in Patients With Relapsed or Refractory Acute Myeloid Leukemia

open access: yesAmerican Journal of Hematology, Volume 101, Issue 5, Page 1019-1024, May 2026.
ABSTRACT Preclinical studies showed a synergistic antileukemia activity with combination of selective XPO1 inhibitor selinexor (SEL) and venetoclax (VEN), with potential to overcome VEN resistance by reducing the anti‐apoptotic protein MCL1. In an investigator‐sponsored, open‐label, phase Ib study (NCT03955783), adult patients with relapsed or ...
Somedeb Ball   +11 more
wiley   +1 more source

Pumping Speed Measurement and Analysis for the Turbo Booster Pump

open access: yesInternational Journal of Rotating Machinery, 2004
This study applies testing apparatus and a computational approach to examine a newly designed spiral-grooved turbo booster pump (TBP), which has both volume type and momentum transfer type vacuum pump functions, and is capable of operating at optimum ...
R. Y. Jou, S. C. Tzeng, J. H. Liou
doaj   +1 more source

Modeling the Delivery of Mercury's Polar Ice by a Volatile‐Rich Impact

open access: yesJournal of Geophysical Research: Planets, Volume 131, Issue 5, May 2026.
Abstract Permanently shadowed regions near Mercury's poles are thought to harbor significant deposits of water ice, the origin of which remains to be conclusively determined. One leading hypothesis is that most of the water observed today may have been delivered by a relatively recent, volatile‐rich impact comparable in scale and age to that which ...
Parvathy Prem   +5 more
wiley   +1 more source

Transport of Water in a Transient, Impact‐Generated Atmosphere on Mercury

open access: yesJournal of Geophysical Research: Planets, Volume 131, Issue 5, May 2026.
Abstract Mercury's polar cold traps host water ice deposits that are likely populated with impact‐delivered water via Mercury's exosphere. However, Mercury's near‐sun location experiences an extremely high photodestruction rate that rapidly destroys water with a timescale of only ∼3.5 hr.
J. K. Steckloff   +4 more
wiley   +1 more source

Adherence to Clotting Factor Prophylaxis in Adolescent and Adult Males With Haemophilia

open access: yesHaemophilia, Volume 32, Issue 3, Page 739-747, May/June 2026.
ABSTRACT Introduction Clotting factor prophylaxis remains the most prescribed standard‐of‐care treatment for people with haemophilia (PwH). Prophylaxis prevents bleeds, joint damage, and improves quality of life (QoL). Its success depends on treatment adherence, consisting of socioeconomic, behavioural, and disease‐ or therapy‐related factors.
Nathália Martins Beserra   +9 more
wiley   +1 more source

Efficient prediction of aerodynamic forces in rarefied flow using convolutional neural network based multi-process method

open access: yesMachine Learning: Science and Technology
The direct simulation Monte Carlo (DSMC) is a widely used approach for studying aerodynamics effects of rarefied flows, but it is highly time-consuming and may exhibit statistical fluctuations.
Haifeng Huang   +9 more
doaj   +1 more source

Application of the DSMC method to astrophysical flows

open access: yes, 2001
2 pages, to appear in the proceedings of the IAU Symp. 208, "Astrophysical Supercomputing Using Particles", eds. J.
Matsuda, Takuya   +2 more
openaire   +2 more sources

“Steak Dry Aging”: An Innovative Approach to Producing High‐Yield, High‐Quality Dry‐Aged Beef

open access: yesJournal of Food Science, Volume 91, Issue 4, April 2026.
ABSTRACT This study evaluated a novel steak dry‐aging (StDA) protocol in which portioned beef steaks were dry‐aged until reaching an average weight loss of 15% and subsequently wet‐aged to achieve a total aging time of either 14 or 28 days. The new protocol was compared with conventional dry aging (DA) for 28 days and unaged controls.
Jean Carlos dos Santos   +7 more
wiley   +1 more source

Combined therapy with dutasteride and tadalafil vs dutasteride or tadalafil monotherapy in benign prostatic hyperplasia: a randomised phase III trial

open access: yesBJU International, Volume 137, Issue 4, Page 698-707, April 2026.
Objectives To evaluate the efficacy and safety of a fixed‐dose combination (FDC) of dutasteride and tadalafil vs monotherapy in patients with benign prostatic hyperplasia (BPH). Patients and Methods This phase III trial enrolled 667 patients. After screening and washout, eligible patients were stratified by the baseline International Prostate Symptom ...
Seung Wook Lee   +20 more
wiley   +1 more source

Chemistry Composition and Bioaccessibility Study of Phenolic Compounds and Carotenoids of New Brazilian Biofortified Sweet Potato “CIP BRS Nuti”

open access: yesFood Chemistry International, Volume 2, Issue 1, Page 23-33, March 2026.
Phenolic compounds of sweet potato CIP BRS Nuti were evaluated for the first time. Catechin, epicatechin, and procyanidin B1 exhibited high bioaccessibility. ABSTRACT Sweet potatoes biofortified in carotenoids have been an alternative to combat malnutrition in vulnerable populations. This work is the first comprehensive study of the bioactive potential
Maria Carla Cândido da Silva   +7 more
wiley   +1 more source

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