Results 71 to 80 of about 149,842 (161)
Frontiers in Marine Science, 2020 The dinoflagellate genus Prorocentrum is globally represented by a wide variety of species found upon benthic and/or epiphytic substrates. Many epibenthic Prorocentrum species produce lipophilic polyether toxins, some of which act as potent protein ...
Ulrike I. Tarazona-Janampa +12 more
doaj +1 more source
Pharmacokinetic profiling of imatinib in relation to CYP3A4 activity in leukaemia patients
British Journal of Clinical Pharmacology, Volume 92, Issue 10, Page 3375-3386, October 2026.Aim Imatinib pharmacokinetics exhibit large interindividual variability because of differences in CYP3A4 activity—the main imatinib‐metabolizing enzyme. While therapeutic drug monitoring is effective, it requires steady‐state conditions and frequent sampling.
Anna Sofie Buhl Rasmussen +14 more
wiley +1 more source
Acknowledgement to Reviewers of Toxins in 2014
, 2015 The editors of Toxins would like to express their sincere gratitude to the following reviewers for assessing manuscripts in 2014:[...
Toxins Editorial Office
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Role of Uremic Toxins in Early Vascular Ageing and Calcification
, 2021 In patients with advanced chronic kidney disease (CKD), the accumulation of uremic toxins, caused by a combination of decreased excretion secondary to reduced kidney function and increased generation secondary to aberrant expression of metabolite genes ...
Kyriakidis, NC +9 more
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FEBS Letters, Volume 600, Issue 17, Page 2579-2614, September 2026.Inositol pyrophosphates are energy‐rich signaling molecules that perform critical functions in cells. Three different families of phosphatases hydrolyze the β phosphate of the inositol pyrophosphate molecules: two have narrow specificities and one is promiscuous.
Ronda J. Rolfes
wiley +1 more source
Mutant NPM1 in Acute Myeloid Leukemia Initiation and Maintenance
Aging and Cancer, Volume 7, Issue 3, Page 109-124, September 2026.NPM1 mutations drive acute myeloid leukemia by acting as neomorphic transcriptional regulators that cooperate with Menin–MLL and XPO1 to sustain HOX/MEIS1 expression and block differentiation. Targeting these mutant‐specific transcriptional dependencies provides a rational therapeutic strategy for NPM1‐mutated AML.
Yanan Jiang +3 more
wiley +1 more source
Advanced Functional Materials, Volume 36, Issue 71, 3 September 2026.An intrinsic photoactive star‐shaped zinc phtalocyanine‐poly(L‐glutamic acid) (ZnPc‐PGA) nanoplatform for multimodal glioblastoma (GBM) therapy and brain‐targeted elivery. A ZnPc‐PGA‐based multifunctional theranostic nanocarrier platform enables image‐guided, multimodal GBM therapy. ZnPc‐PGA nanocarriers support the integration of fluorescence imaging,
Amina Benaicha‐Fernández +14 more
wiley +1 more source
Yessotoxins, a Group of Marine Polyether Toxins: an Overview
Marine Drugs, 2008 Yessotoxin (YTX) is a marine polyether toxin that was first isolated in 1986 from the scallop Patinopecten yessoensis. Subsequently, it was reported that YTX is produced by the dinoflagellates Protoceratium reticulatum, Lingulodinium polyedrum and ...
José J. Fernández +5 more
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Marine Drugs, 2007 In the context of the French Phytoplankton and Phycotoxins MonitoringNetwork (REPHY) programme, shellfish samples were harvested from different locationswhere harmful algae blooms were known to have occurred.
Eric Abadie +4 more
doaj +1 more source
Membrane‐Damaging Toxins: Family of RTX Toxins
, 2003 The major cellular effect of RTX toxins has been ascribed to their pore‐forming capacity, resulting in plasma membrane lesions and osmotic lysis.
Oxhamre, C, Richter‐Dahlfors, A
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