Results 121 to 130 of about 75,570 (227)

Surgical Outcomes Following Neoadjuvant‐Targeted Therapy for Advanced Differentiated Thyroid Cancer—Real‐World Data

Clinical Endocrinology, Volume 104, Issue 3, Page 270-280, March 2026.
ABSTRACT Background Differentiated thyroid carcinoma (DTC) is typically managed surgically with favourable outcomes. However, surgery may have dire consequences when the tumour invades critical structures. Neoadjuvant therapy with tyrosine kinase inhibitors (TKIs) has emerged as a potential strategy to improve resectability and reduce morbidity in ...
Alexandra Dorman, Genady Shendler, Anton Warshavsky, Nidal Muhanna, Gilad Horowitz, Liyona Kampel Furman, Shahaf Shilo, Ben‐Zion Joshua, Eran Alon, Eric Remer, Galit Avior, Avi Khafif, Orit Gutfeld, Elena Izkhakov, Jobran Mansour, Inbar Finkel   +15 more
wiley   +1 more source

A novel single‐cell NAD‐ME C4 subtype integrated with CAM and bicarbonate use in an aquatic plant

New Phytologist, Volume 249, Issue 5, Page 2386-2401, March 2026.
Summary Many plants maximize photosynthesis by using a CO2‐concentrating mechanism (CCM). Based on physiology, the freshwater plant Ottelia alismoides has three CCMs: C4 metabolism (NAD‐malic enzyme (NAD‐ME) subtype) and bicarbonate‐use during the day plus crassulacean acid metabolism (CAM) at night and lacks Kranz anatomy. Here, we combined a range of
Hong Sheng Jiang, Wenmin Huang, Shijuan Han, Pengpeng Li, Zuying Liao, Liyuan Wei, Lei Zhao, Shuping Gu, Jun Ding, Brigitte Gontero, Stephen C. Maberly, Wei Li   +11 more
wiley   +1 more source

Reskilling Capability: An Exploration of Skills Renewal in the Swedish Automotive Industry

R&D Management, Volume 56, Issue 2, Page 326-337, March 2026.
ABSTRACT This paper explores the antecedents and conditions of a reskilling capability in organisations. Technological shifts, especially during discontinuous technological change (DTC), require new skills. Yet, firms may simultaneously experience skills shortages and worker displacement, while skills shortages can inhibit innovation.
Elina Gobena, Matti Kaulio, Mattias Wiggberg   +2 more
wiley   +1 more source

TERT promoter mutations contribute to adverse clinical outcomes and poor prognosis in radioiodine refractory differentiated thyroid cancer

Scientific Reports
Telomerase reverse transcriptase promoter (TERTp) mutations are associated with non-radioiodine avidity. However, the role of these mutations in the clinical outcomes of patients with radioiodine-refractory differentiated thyroid cancer (RAIR-DTC ...
Gongxun Tan, Bingquan Jin, Xiaoqin Qian, Yuguo Wang, Guoliang Zhang, Enock Adjei Agyekum, Feng Wang, Liang Shi, Yue Zhang, Zhenwei Mao, Chunhe Shi, Ying Xu, Xiuying Li, Lele Zhang, Shaohua Li   +14 more
doaj   +1 more source

Pleural metastases from differentiated thyroid cancer: clinical features and long-term outcomes

European Thyroid Journal
Objective: Pleural metastasis (PM) is rare in patients with differentiated thyroid cancer (DTC). Radioiodine (131I) therapy has been the main treatment for postoperative metastasis and recurrence of DTC. However, clinical data on PM from DTC are limited.
Mengyue Liu, Juan Tang, Nan Sun, Chuang Xi, Chentian Shen, Song Hongjun, Quanyong Luo, Xianzhao Deng, Zhongling Qiu   +8 more
doaj   +1 more source

Tunable Patterned Blue Phase Liquid Crystals Based on Lithographic Process Technology

Advanced Optical Materials, Volume 14, Issue 6, 9 February 2026.
A patterned blue phase liquid crystal device with electrically driven, localized bistability is demonstrated using a cost‐efficient photolithographic dual‐alignment process. The device switches between a high‐contrast patterned state and a uniform reflective state.
Jia‐Yu Cao, Ting‐Mao Feng, Duan‐Yi Guo, Liang‐Ying Wu, Aleksandra Neumann, Kamil Orzechowski, Chun‐Ta Wang   +6 more
wiley   +1 more source

Distinct alterations of adiponectin, fibroblast growth factor 21 (FGF‐21), and insulin‐like growth factor binding protein 2 (IGFBP‐2) link dysmetabolism with cognitive decline across the Alzheimer's disease spectrum

Alzheimer's &Dementia, Volume 22, Issue 2, February 2026.
Abstract INTRODUCTION Metabolic disorders are risk factors for Alzheimer's disease (AD), although underlying mechanisms remain unclear. We investigated the relationship between peripheral metabolic markers – adiponectin, fibroblast growth factor 21 (FGF‐21), and insulin‐like growth factor binding protein 2 (IGFBP‐2) – and AD.
Caroline Dallaire‐Théroux, Helena L. Denis, Rosalie Cottez, Cyntia Tremblay, Amélie Provencher, Josue Valentin‐Escalera, Manon Leclerc, Andreanne Loiselle, Marine Tournissac, Olivier Potvin, Sylvie Belleville, Anne Gangloff, Frederic Picard, Henrik Zetterberg, Consortium for the Early Identification of Alzheimer's Disease – Quebec (CIMA‐Q), Frédéric Calon   +15 more
wiley   +1 more source

Relative burden of cancer and noncancer mortality among long-term survivors of differentiated thyroid cancer in the US

Frontiers in Endocrinology
BackgroundLimited information is available regarding the relative risks of cancer-specific mortality and noncancer-specific mortality among long-term survivors with differentiated thyroid cancer (DTC).MethodsIn this retrospective study, nationwide data ...
Yang Shi, Chengzhou Lv, Pai Liu, Yuenan Zheng, Hao Zhang, Wenwu Dong, Ping Zhang   +6 more
doaj   +1 more source

Bone Metastasis: Molecular Mechanisms, Clinical Management, and Therapeutic Targets

MedComm, Volume 7, Issue 2, February 2026.
This figure emphasizes current understanding of the regulatory networks, approach of diagnose, available preclinical models and clinical management of bone metastasis. to guide future therapeutic development. A deep understanding of these aspects enables the prevention of bone metastasis and the implementation of effective therapeutic strategies ...
Jingyuan Wen, Binghua Li, Shengjia Wang, Yongzhong Yao, Zhao Huang, Decai Yu   +5 more
wiley   +1 more source

Faecal microbiome, gastrointestinal integrity, inflammation and thermoregulation in recent exertional heat illness patients and matched controls

Experimental Physiology, Volume 111, Issue 2, Page 403-425, 1 February 2026.
Abstract The gastrointestinal (GI) microbiota and GI barrier integrity are hypothesised to contribute to exertional heat illness (EHI) aetiology. We compared the faecal microbiome, GI barrier integrity, inflammation and thermoregulation of 29 recent (∼4 months) EHI patients (a group with elevated EHI risk) and 29 control individuals without prior EHI ...
Alex A. M. Gould, Neil P. Walsh, Michael J. Tipton, Michael J. Zurawlew, Omar Tayari, Carol House, Simon K. Delves, Samuel C. Robson, Janis J. Shute, Joy E. M. Watts, Andrew J. Roberts, Alex J. Rawcliffe, Megan R. Robinson, Jo Corbett   +13 more
wiley   +1 more source