Results 121 to 130 of about 75,803 (186)

Interpretable LightGBM model with SHAP analysis predicts non‐excellent response to initial radioiodine therapy in differentiated thyroid carcinoma

Journal of Applied Clinical Medical Physics, Volume 27, Issue 4, April 2026.
Abstract Purpose To identify independent determinants influencing therapeutic outcomes of initial radioactive iodine (131I) therapy in differentiated thyroid carcinoma (DTC) and establish an interpretable predictive framework for clinical decision‐making.
Zhaoxia Luo, Yangyang Lei, Qing Zhang
wiley   +1 more source

Risk of cardiac, neuropsychiatric and musculoskeletal adverse events with levothyroxine: Systematic review

British Journal of Clinical Pharmacology, Volume 92, Issue 4, Page 1023-1039, April 2026.
Abstract Levothyroxine (LT4) is the standard treatment for hypothyroidism and the most widely prescribed medication worldwide. Although generally safe, regulatory reports list potential cardiac, neuropsychiatric and musculoskeletal adverse events (AEs). Clarifying their clinical relevance is essential.
Bala Swetha Baskaran, Mohammad Ali Omrani, Flory T. Muanda   +2 more
wiley   +1 more source

TERT promoter mutations contribute to adverse clinical outcomes and poor prognosis in radioiodine refractory differentiated thyroid cancer

Scientific Reports
Telomerase reverse transcriptase promoter (TERTp) mutations are associated with non-radioiodine avidity. However, the role of these mutations in the clinical outcomes of patients with radioiodine-refractory differentiated thyroid cancer (RAIR-DTC ...
Gongxun Tan, Bingquan Jin, Xiaoqin Qian, Yuguo Wang, Guoliang Zhang, Enock Adjei Agyekum, Feng Wang, Liang Shi, Yue Zhang, Zhenwei Mao, Chunhe Shi, Ying Xu, Xiuying Li, Lele Zhang, Shaohua Li   +14 more
doaj   +1 more source

Morphological Stasis in Wing Traits Despite Species Diversification in African and Malagasy Miniopterus Bats

Ecology and Evolution, Volume 16, Issue 4, April 2026.
This study evaluates whether diversification in Malagasy and African Miniopterus is associated with divergence in linear wing morphology. Principal component and morphospace analyses indicate that wing morphology is highly conserved across species, with most variation reflecting differences in size rather than shape.
Stefania Briones, Roberta Mason‐Gamer, Steven M. Goodman, Terrence C. Demos, Paul W. Webala, Bruce D. Patterson   +5 more
wiley   +1 more source

Relative burden of cancer and noncancer mortality among long-term survivors of differentiated thyroid cancer in the US

Frontiers in Endocrinology
BackgroundLimited information is available regarding the relative risks of cancer-specific mortality and noncancer-specific mortality among long-term survivors with differentiated thyroid cancer (DTC).MethodsIn this retrospective study, nationwide data ...
Yang Shi, Chengzhou Lv, Pai Liu, Yuenan Zheng, Hao Zhang, Wenwu Dong, Ping Zhang   +6 more
doaj   +1 more source

Expanding Access to Genome Sequencing: Higher Diagnostic Yield in Self‐Referred Participants From the CincyKidsSeq Study and Implications for Hybrid Models of Genetic Service Delivery

Clinical Genetics, Volume 109, Issue 4, Page 717-724, April 2026.
Genome sequencing helped find answers for 1 in 5 children with rare conditions in an outpatient study looking at hybrid genetic care delivery. Families who chose testing themselves had the highest diagnostic yield, showing that self‐referral may be a helpful way to improve access to genetic care.
Kristin Theobald, Amelle Shillington, Farrah Jackson, Jaime Lopes, Casey J. Brewer, Brian Dawson, Gang Wu, James Denton, Mike Pauciulo, Xue Zhang, Anne Slavotinek   +10 more
wiley   +1 more source

Seasonal and Interannual Variation of Common Dolphin, Delphinus delphis, Density in Portuguese Waters

Marine Mammal Science, Volume 42, Issue 2, April 2026.
ABSTRACT Modeling a species' ecology and abundance provides important insights into its habitat preferences, population trends, and distribution. Here, we studied how environmental factors relate to common dolphin (Delphinus delphis) density in waters off mainland Portugal.
Miguel P. Martins, Marc Fernandez, Ana Marçalo, Nuno Oliveira, Tiago A. Marques   +4 more
wiley   +1 more source

The Diarylprolinol Silyl Ethers: After 20 Years Still Opening New Doors in Asymmetric Catalysis

Angewandte Chemie, Volume 138, Issue 11, 9 March 2026.
Catalysis Rules! The year 2025 marks the 20th anniversary of diarylprolinol silyl ethers in asymmetric organocatalysis. During the first decade after their discovery, these catalysts have been established as one of the most versatile tools in aminocatalysis. Although now considered mature, recent years have witnessed renewed innovation.
Enrico Marcantonio, René Slot Bitsch, Karl Anker Jørgensen   +2 more
wiley   +2 more sources

Evaluating the Efficacy of Polyphenol‐Enriched Plant Extracts and Pathway Modulators in the Bone Marrow to Suppress Breast Cancer Progression

The FASEB Journal, Volume 40, Issue 6, 31 March 2026.
The combined therapy decreased inflammatory and angiogenic signaling and altered bone marrow cell profiles linked to tumor dormancy, indicating a potential approach to limit disease progression and reduce relapse risk in breast cancer. ABSTRACT Disseminated tumor cells (DTCs) in the bone marrow can survive in a dormant state and later reawaken to drive
Hayarpi Javrushyan, Gayane Petrosyan, Marika Mróz, Barbara Kusznierewicz, Yem Alharithi, Mikayel Ginovyan, Alina Maloyan, Nikolay Avtandilyan   +7 more
wiley   +1 more source

Revealing the Energy Level and Charge Dynamics Interplay in Mixed Pb‐Sn Perovskite Solar Cells with Novel Phenoxazine and Phenothiazine Self‐Assembled Monolayers

Solar RRL, Volume 10, Issue 6, 29 March 2026.
Carbazole‐based self‐assembled monolayers (SAMs) have proven effective as HTLs in perovskite solar cells (PSCs). However, the energy alignment with narrow‐bandgap lead‐tin (Pb‐Sn) perovskites is suboptimal. Here, we design four phenoxazine/phenothiazine SAMs.
Daniele T. Cuzzupè, Marius Franckevičius, Orestis Karalis, Yekitwork Abebe Temitmie, Mantas Marčinskas, Maria Azhar, Neethinathan Johnee Britto, Timo Eberle, Denis Andrienko, Vytautas Getautis, Tadas Malinauskas, Hannes Hempel, Lukas Schmidt‐Mende   +12 more
wiley   +1 more source