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Assessment of glymphatic function in narcolepsy using DTI-ALPS index
Sleep Medicine, 2023Sleep is a modulator of glymphatic activity which is altered in various sleep disorders. Narcolepsy is a sleep disorder characterized by excessive daytime sleepiness (EDS), rapid onset of rapid eye movement (REM) sleep, cataplexy, disturbed night sleep with fragmentation.
Ekim Gumeler +4 more
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Parenchymal CSF Fraction and DTI‐ALPS in Brain Aging
Alzheimer's & Dementia, 2022AbstractBackgroundThe perivascular space (PVS) functions as part of a brain clearance system that drains interstitial fluid and solutes including Aβ and tau from brain parenchyma and is associated with the development of AD. Recent developed imaging tools of cerebral parenchymal CSF fraction (CSFF)1 and diffusion tensor imaging along perivascular ...
Liangdong Zhou, Thanh D Nguyen, Yi Li
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Glymphatic system dysfunction in obstructive sleep apnea evidenced by DTI-ALPS
Sleep Medicine, 2022This study aimed to evaluate the glymphatic system function in patients with obstructive sleep apnea (OSA) compared to healthy controls using diffusion tensor imaging (DTI) with the perivascular space (DTI-ALPS) method. Our hypothesis is that patients with OSA may have glymphatic system dysfunction, which is correlated with OSA severity.We enrolled 24 ...
Ho-Joon, Lee +3 more
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Journal of Neuroradiology, 2023
While the occurrence of glymphatic system dysfunction has been observed in temporal lobe epilepsy (TLE), the potential asymmetry of this system has yet to be investigated in the TLE context. We aimed to investigate the glymphatic system function in both hemispheres and to analyze asymmetric features of the glymphatic system in TLE patients using ...
Wenzhen Zhu, Suiqiang Zhu, Xu Zhao
exaly +3 more sources
While the occurrence of glymphatic system dysfunction has been observed in temporal lobe epilepsy (TLE), the potential asymmetry of this system has yet to be investigated in the TLE context. We aimed to investigate the glymphatic system function in both hemispheres and to analyze asymmetric features of the glymphatic system in TLE patients using ...
Wenzhen Zhu, Suiqiang Zhu, Xu Zhao
exaly +3 more sources
Decreased DTI-ALPS Index in Delirium: A Preliminary MRI Study
NeuroradiologyDelirium is linked to brain abnormalities, yet the role of the glymphatic system is not well understood. This study aims to examine alterations in brain physiology in delirium by using diffusion-tensor imaging (DTI) to assess water diffusion along the perivascular space (ALPS) and to explore its correlation with clinical symptoms.We examined 15 ...
Fei Xiong, Ye Tu, Xiaoyun Fu
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DTI-ALPS Index as a Predictor of Cognitive Decline Over 1 Year
NeuroradiologyAlzheimer's disease (AD) is a progressive neurodegenerative disorder characterized by cognitive decline and impaired daily functioning. The glymphatic system removes neurotoxic waste, including amyloid-beta (Aβ), an important factor in AD pathogenesis.
Jeonghwan Lee, Chi-Hoon Choi
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Lower DTI-ALPS Index in Patients With Major Depressive Disorder: Correlation With Fatigue
Behavioural Brain ResearchDiffusion tensor imaging along perivascular spaces (DTI-ALPS) is an index that may provide insights into intracranial waste clearance processes. Glymphatic system dysfunction has been suggested to play a role in the development of major depressive disorder (MDD).
Jiajun Xu, Peiwei Xu
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