Porphyrins, previously linked only to acne inflammation, are now implicated in skin ageing. Their presence correlates with increased melanin, inflammation, and oxidative stress, contributing to premature ageing signs. This study introduces the concept of “Porphyr'ageing,” highlighting the detrimental effects of bacterial metabolites on skin health and ...
Marie Meunier +9 more
wiley +1 more source
Design, Synthesis, and Structural Evolution of Pseudo‐Natural Product IDO1 Inhibitors and Degraders
The combination of bicyclic monoterpene‐ and pyrrolidine‐alkaloid fragments yields novel pseudo‐natural products. Biological characterization revealed that these iDegs are inhibitors and degraders of indoleamine‐2,3‐dioxygenase. Abstract Terpenoid alkaloids are derived from the fusion of structurally diverse terpenoid‐ and alkaloid moieties.
Xiu‐Fen Cheng +19 more
wiley +2 more sources
Ratiometric Mechano-Fluorescent Elastomers Dually Promoted via Effective Force-Triggered Radicals and Preeminent Toughnesses/Stretchabilities by Unconventional Shuttling Dimensions of Tetraphenylethylene-Suspended [c2] Daisy Chain Rotaxanes. [PDF]
Cuc TTK +9 more
europepmc +1 more source
Patient needs and preferences for a kidney stone self-monitoring app: a pilot survey analysis. [PDF]
Mahmood DT, Richards HL, Hennessey DB.
europepmc +1 more source
Relação da DTM dolorosa com a função de fala: Quais as possíveis características de movimentos mandibulares e os principais sintomas relatados? [PDF]
Melissa de Oliveira Melchior +2 more
openalex +1 more source
ABSTRACT Mixed beaches containing anthropogenic geomaterials such as bricks, concrete, glass, ceramics, tarmac and slag are globally understudied. These materials enter natural beach systems through erosion or dumping, and rising sea levels and increased storminess are expected to intensify coastal erosion, reworking and re‐exposing previously dumped ...
Yuchen Wang +5 more
wiley +1 more source
Short-term effect after soft tissue manipulation session on subjective and objective parameters in office workers with chronic low back pain: A randomized clinical trial. [PDF]
Wendt M, Rubach J, Waszak M.
europepmc +1 more source
ABSTRACT This study examined GPS positioning accuracy in high‐density urban environments using Hong Kong as a representative case study. Through field measurements along 32 testing routes using three GPS devices, we evaluated GPS performance across diverse urban morphologies to assess associations between complex urban characteristics and positioning ...
Tianyu Li, Yanjia Cao, Grant McKenzie
wiley +1 more source
UAV-derived building heights and floor counts for the University of Texas at Dallas (July 2025 dataset). [PDF]
Tian S, Qiu F.
europepmc +1 more source
Analytical solutions of 21-dimensional Burgers equation with damping term by HPM,ADM and DTM [PDF]
K. Sathya +2 more
openalex +1 more source

