Results 121 to 130 of about 213,927 (300)

Suppression of lung adenocarcinoma migration through organelle alkalization by human lactoferrin – albumin fusion

FEBS Open Bio, EarlyView.
This paper reveals how human lactoferrin–albumin fusion (hLF‐HSA) potently suppresses lung adenocarcinoma cell migration. hLF‐HSA upregulates NHE7, leading to Golgi alkalization, disruption of the Golgi secretome, downregulation of MMP1, and reversal of EMT. These findings suggest a novel Golgi‐targeting strategy to suppress cancer cell migration.
Hana Nopia, Masahiro Kimura, Daisuke Kurimoto, Atsushi Sato   +3 more
wiley   +1 more source

Multi-Resonator Dual-Band Filters on Dielectric Resonators [PDF]

, 2015
In the current article the concept of multi-resonator dual-band filter has been described. The dual-band filters based on three and four rectangular dielectric resonators have been synthesized that functionate in ТЕ01δ and ТЕ02δ modes.
Pidhurska, Tatyana V.
core  

YIPFα1A expression is regulated by multilayered molecular mechanisms

FEBS Open Bio, EarlyView.
YIPFα1A, a five‐pass Golgi protein, is regulated at multiple layers. (1) Rare‐codon enrichment drives translation‐coupled mRNA decay. (2) A proximal 3′‐UTR element stabilizes mRNA. (3) A distal 3′‐UTR element included by alternate poly(A) site usage represses translation, which can be overridden by the proximal 3′‐UTR element.
Tokio Takaji, Yurika Nakanishi, Nobuhiro Nakamura   +2 more
wiley   +1 more source

Dual‐band single‐layer substrate‐integrated waveguide filtering antennas with independently controllable bands

IET Microwaves, Antennas & Propagation
A novel design method of dual‐band single‐layer substrate‐integrated waveguide (SIW) filtering antennas with independently controllable bands is proposed in this paper. The basic two‐pole dual‐band filtering antenna is proposed by a dual‐mode rectangular
Ke Gong, Jia Liu, Chunfeng Fan, Xuehui Hu, Jintu Sun, Yan Liu, Shuang Chen, Qing Liu   +7 more
doaj   +1 more source

Dual-Band Antenna With Pattern and Polarization Diversity

Sensors
In this letter, we propose a pattern-diversity antenna with different radiation patterns at two different frequency bands (f1 and f2) (f1: broadside radiation pattern, f2: conical radiation pattern). The proposed structure consists of a central circular antenna and two annular ring antennas; each of the three antennas has individual ports.
Jungmin Mo, Youngje Sung
openaire   +3 more sources

Identifying transcription factors controlling the basal expression of human MRP4 highlights a substantial role for Sp1

FEBS Open Bio, EarlyView.
The MRP4 transporter exports several drugs and signaling molecules. Here, we identified key promoter elements regulating basal MRP4 expression. Using reporter assays, we defined a conserved region with essential Sp1 and contributory Ets sites, which controlled basal MRP4 expression.
Debora Singer, Angelique Kragl, Katrin Ziems, Juliane Glaubitz, Sophie Grammbauer, Susanne Hildebrandt, Mladen V. Tzvetkov, Gabriele Jedlitschky   +7 more
wiley   +1 more source

Derivation and characterization of retinal pigment epithelium from urine‐derived iPSCs

FEBS Open Bio, EarlyView.
Age‐related macular degeneration causes vision loss via RPE dysfunction and loss. Traditional iPSC therapies rely on invasive biopsies, limiting scalability. Here, we utilize urine‐derived stem cells as an accessible source to generate u‐iPSCs, successfully differentiated into pigmented RPE. This “Urine‐to‐Retina” platform provides a promising path for
Daniella Beiner, Hainan Zhu, Carol Christine Bosholm, Heuy‐Ching Wang, Tracy Criswell, Anthony Atala, Jian‐Xing Ma, Yuanyuan Zhang   +7 more
wiley   +1 more source

Dual-band transmission polarization conversion metasurface and its reconfigurable-phase design

Results in Physics
Although abundant transmission polarization conversion metasurfaces (T-PCMs) have been reported, a dual-band T-PCM has only received little attention. Moreover, a reconfigurable-phase design of the T-PCMs is limited to a single-frequency band operation ...
Zexu Guo, Yulong Zhou, Huanhuan Yang, Sijia Li, Tong Li, Xiangyu Cao   +5 more
doaj   +1 more source

Molecular dynamics simulations of positively selected codons in FcγRI reveal novel biochemical binding properties

FEBS Open Bio, EarlyView.
Evolutionary analysis across 32 placental mammals identified positive selection at residues H148 and W149 in the immune receptor FcγR1. Ancestral reconstruction combined with molecular dynamics simulations reveals how these mutations may influence receptor structure and dynamics, providing insight into the evolution of antibody recognition and immune ...
David A. Young, Omar Arias‐Gaguancela, Fiona Gibson, Morgan Grainger, Jodie Score, Amit Nathubhai, Mauricio Cafiero, Lee Richard Machado   +7 more
wiley   +1 more source

Design and simulated characterization of the dual-band polarizer based on metasurface structure

AIP Advances
Dual-band polarizers must simultaneously exhibit high transmittance and bandwidth efficiency in fields such as polarization navigation and efficient detection. However, in most studies, the detection of dual bands is inefficient.
Hangwei Zhu, Yanlin He, Shuning Wang, Lidan Lu, Lianqing Zhu   +4 more
doaj   +1 more source