Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining
IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis +3 more
wiley +1 more source
Multi-Channel Super-Resolution Reconstruction Model Based on Dual-Band Weather Radar Fusion
Dual-band weather radar networks enable complementary multi-radar observations, improving the accuracy, three-dimensional characterization, and early warning capability for severe convective weather.
Siran Yang +6 more
doaj +1 more source
Amplificadores clase CE de doble banda con estructuras basadas en líneas CRLH y ECRLH. [PDF]
In this paper the use of Composite Right/Left Hand (CRLH) and Extended Composite Right/Left Hand (ECRLH) transmission lines in dual band power amplifiers is proposed.
Arqués Orobón, Francisco José +4 more
core +1 more source
CRISPRI‐mediated gene silencing and phenotypic exploration in nontuberculous mycobacteria. In this Research Protocol, we describe approaches to control, monitor, and quantitatively assess CRISPRI‐mediated gene silencing in M. smegmatis and M. abscessus model organisms.
Vanessa Point +7 more
wiley +1 more source
Nuclear pore links Fob1‐dependent rDNA damage relocation to lifespan control
Damaged rDNA accumulates at a specific perinuclear interface that couples nucleolar escape with nuclear envelope association. Nuclear pores at this site help inhibit Fob1‐induced rDNA instability. This spatial organization of damage handling supports a functional link between nuclear architecture, rDNA stability, and replicative lifespan in yeast.
Yamato Okada +5 more
wiley +1 more source
A Novel Concentric Annular-Ring Slot Dual-Band Circularly Polarized Microstrip Antenna
A simple structure concentric annular-ring slot dual-band circularly polarized (CP) microstrip antenna operating at ISM band (2.45 GHz) and 5G band (3.5 GHz) is proposed in this paper.
Yong Cheng, Hui Liu
doaj +1 more source
Single‐molecule DNA flow‐stretch assays for high‐throughput DNA–protein interaction studies
We describe an optimised single‐molecule DNA flow‐stretch assay that visualises DNA–protein interactions in real time. Linear DNA fragments are tethered to a surface and stretched by buffer flow for fluorescence imaging. Using λ and φX174 DNA, this protocol enhances reproducibility and accessibility, providing a versatile approach for studying diverse ...
Ayush Kumar Ganguli +8 more
wiley +1 more source
Dual band, low profile and compact tunable frequency selective surface with wide tuning range
In this paper, a dual polarized, dual band, low profile, embedded bias network, and compact tunable varactor band pass frequency selective surface (FSS) is designed with a wide tuning range.
Mohammad-Ali-Nezhad, Sajad +3 more
core +1 more source
Screening and epitope characterization of Nidogen‐2‐specific nanobodies
Camel immunization and phage display were employed to generate high‐affinity VHH nanobodies against Nidogen‐2. After library construction, biopanning, ELISA screening, sequencing, and recombinant expression, selected nanobodies were purified and characterized, leading to the preliminary exploration of a nanobody‐based sandwich ELISA for specific ...
Jianchuan Wen +9 more
wiley +1 more source
Single-, Dual- and Triple-band Frequency Reconfigurable Antenna [PDF]
The paper presents a frequency reconfigurable slot dipole antenna. The antenna is capable of being switched between single-band, dual-band or triple-band operation.
Hamid, M. R. +5 more
core +1 more source

