Results 31 to 40 of about 26,946 (267)
Liquid biopsy‐based diagnostic evaluation of hypermethylated CpG sites for ovarian cancer diagnosis
Molecular Oncology, EarlyView.This schematic outlines the workflow from biomarker identification to duplex MethyLight assay validation for epithelial ovarian cancer diagnosis using cfDNA‐based liquid biopsy. Initial screening of hypermethylated CpG candidates (cg02957270, cg10061138 cg00480298, COL2A1) was performed in tissue using ARMS‐PCR, COBRA, qPCR and image analysis. Selected
Deepa Bisht +3 more
wiley +1 more source
Acute caffeine treatment protects the developing retina from ischemia‐induced cell death
FEBS Open Bio, EarlyView.Caffeine reduces cell death in the developing retina under ischemia (OGD). This effect does not involve BDNF upregulation or antioxidant pathways (NRF2/VEGF). Neuroprotection occurs mainly through adenosine A2A receptor antagonism, decreasing glutamate release and excitotoxicity, highlighting caffeine's potential as an acute neuroprotective agent in ...
Amanda Alves Nascimento +6 more
wiley +1 more source
FEBS Open Bio, EarlyView.Drugs previously repurposed to target blood cancers reduced neuroblastoma and glioblastoma cell growth and viability. However, their levels of anticancer activity were different and their clinical application may be problematic due to side effects at effective doses.
Abhishek Kharawatkar +4 more
wiley +1 more source
FEBS Open Bio, EarlyView.The dual roles of CC and CXC chemokines in distinguishing active, latent, and subclinical tuberculosis were reviewed, along with an evaluation of their potential as diagnostic biomarkers and therapeutic targets to advance precision medicine in tuberculosis management. The graphical abstract was generated with AI assistance (Gemini 3.0).
Xuying Yin, Dangsheng Xiao, Jiezuan Yang
wiley +1 more source
The Corrosion Resistance of The Ukrainian Steel Embedded in Concrete after and before quenching
مجلة النهرين للعلوم الهندسية, 2017 The corrosion resistance of the Ukrainian structural steel(0.22%C) and dual-phase steel which produced from it and embedded in concrete was carried out in this investigation, a test specimens of the Ukrainian steel was prepared and heated to a different ...
Rahi Abed Hassan Al-Obaidy
doaj
Loss of AMBRA1 activates MAPK and angiogenesis signaling pathways in melanoma cells
FEBS Open Bio, EarlyView.Loss of AMBRA1 in melanoma cells activates multiple oncogenic pathways associated with tumor progression. Transcriptomic and protein network analyses revealed that AMBRA1 depletion enhances MAPK/ERK signaling, angiogenesis, TGF‐β/EMT signaling, and Wnt/axon guidance pathways.
Milad Ibrahim +4 more
wiley +1 more source
Diyala Journal of Engineering Sciences, 2019 This research is concerned with study of the effect heat treatment and the bake hardening process on dual phase steels which can be obtain by intercritical annealing process.
Abbas Fadhil Abbas +1 more
doaj +1 more source
Dissimilar Dual Phase-Low Carbon Steel Joints by the GMAW Process Subjected to Impact Load
Metals, 2022 Dissimilar welding used in the automotive area are possible joints with the GMAW process; however, its structural performance must be evaluated.
César M. Gómora +4 more
doaj +1 more source
Aging Is a Key Driver for Adult Acute Myeloid Leukemia
Aging and Cancer, EarlyView.Acute myeloid leukemia (AML) is a classical age‐related hematologic malignancy, and a key driver of AML is aging, which profoundly regulates intrinsic factors such as genomic instability, epigenetic reprogramming, and metabolic dysregulation, and alters bone marrow microenvironment.
Rong Yin, Haojian Zhang
wiley +1 more source
Journal of Manufacturing and Materials Processing, 2019 It is well known that stress-induced phase transformation in dual-phase steel leads to the degradation of bulk corrosion resistance properties. Predicting this behaviour in high carbon steel is imperative for designing this grade of steel for more ...
Wilson Handoko +3 more
doaj +1 more source