Results 31 to 40 of about 748 (219)
An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes
FEBS Letters, EarlyView.GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg +14 more
wiley +1 more source
Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
Molecular Oncology, EarlyView.This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source
Research on strain aging behavior of ultra-high strength dual-phase steel
Heliyon, 2023 The bake hardening value is one of the vital strength indexes of dual-phase steel, representing the strengthening ability of materials after pre-strain and baking, playing an important role in vehicle safety and lightweight design. Studying and improving
Biao Xiao +4 more
doaj +1 more source
Damage in dual phase steels [PDF]
, 2019 In this research, the effect of microstructural features on damage behavior isstudied with a special emphasis on evolution of plastic deformation heterogeneity in microscale. This is carried out by performing experimental and numerical work on a ferritic-martensitic DP600 steel sheet from the AHSS family.The experimental investigations are focused on ...
openaire +1 more source
Liquid biopsy‐based diagnostic evaluation of hypermethylated CpG sites for ovarian cancer diagnosis
Molecular Oncology, EarlyView.This schematic outlines the workflow from biomarker identification to duplex MethyLight assay validation for epithelial ovarian cancer diagnosis using cfDNA‐based liquid biopsy. Initial screening of hypermethylated CpG candidates (cg02957270, cg10061138 cg00480298, COL2A1) was performed in tissue using ARMS‐PCR, COBRA, qPCR and image analysis. Selected
Deepa Bisht +3 more
wiley +1 more source
PANoptosis in the pathogenesis of myelodysplastic syndromes
Molecular Oncology, EarlyView.PANoptosis, a combination of three types of programmed cell death, is mediated by a large protein complex called a PANoptosome. In healthy bone marrow hematopoietic cells, PANoptosis is restricted by inhibitory signaling. In MDS, bone marrow cells become sensitive to the PANoptotic stimuli due to the aberrant inactivation of inhibitory signaling or ...
Rohit Thalla +4 more
wiley +1 more source
The Corrosion Resistance of The Ukrainian Steel Embedded in Concrete after and before quenching
مجلة النهرين للعلوم الهندسية, 2017 The corrosion resistance of the Ukrainian structural steel(0.22%C) and dual-phase steel which produced from it and embedded in concrete was carried out in this investigation, a test specimens of the Ukrainian steel was prepared and heated to a different ...
Rahi Abed Hassan Al-Obaidy
doaj
Acute caffeine treatment protects the developing retina from ischemia‐induced cell death
FEBS Open Bio, EarlyView.Caffeine reduces cell death in the developing retina under ischemia (OGD). This effect does not involve BDNF upregulation or antioxidant pathways (NRF2/VEGF). Neuroprotection occurs mainly through adenosine A2A receptor antagonism, decreasing glutamate release and excitotoxicity, highlighting caffeine's potential as an acute neuroprotective agent in ...
Amanda Alves Nascimento +6 more
wiley +1 more source
Diyala Journal of Engineering Sciences, 2019 This research is concerned with study of the effect heat treatment and the bake hardening process on dual phase steels which can be obtain by intercritical annealing process.
Abbas Fadhil Abbas +1 more
doaj +1 more source
Dissimilar Dual Phase-Low Carbon Steel Joints by the GMAW Process Subjected to Impact Load
Metals, 2022 Dissimilar welding used in the automotive area are possible joints with the GMAW process; however, its structural performance must be evaluated.
César M. Gómora +4 more
doaj +1 more source