Results 51 to 60 of about 748 (219)
Adenosine triphosphate as a modulator of protein interactions and stability
FEBS Open Bio, EarlyView.ATP is best known as the cell's energy currency, but it also shapes how proteins fold, interact, aggregate and form biomolecular condensates. This review explains the emerging physical principles behind these effects, including weak binding to charged protein regions, magnesium‐dependent behaviour and concentration‐dependent control of protein ...
Shuyuan Tan, Robin Curtis
wiley +1 more source
Strength and Fracture Behaviour of Dual Phase Steel Dp450 in Static and Dynamic Conditions
Communications, 2019 In this work, strength and plastic deformation effect of the dual phase steel are analysed in the static and dynamic conditions. Since the dual phase steel is extensively used in the outer body parts of the automotive vehicles, its dynamic strength and ...
Sunil Kumar Meluru Ramesha +1 more
doaj +1 more source
GelMA‐based 3D spheroids recapitulate transcriptomic and functional hallmarks of myeloid sarcoma
FEBS Open Bio, EarlyView.GelMA 5% hydrogels support the formation of myeloid leukemia spheroids that recapitulate MS‐specific features, including G1 arrest, apoptosis, and ECM‐driven transcriptomic reprogramming. The 3D model mimicked soft‐tissue‐like stiffness and oxygen conditions, and transcriptomic convergence with primary MS samples confirmed its utility as a preclinical ...
Nicolas Germain +11 more
wiley +1 more source
Teshugang, 2007 The plane-strain compression test with strain rate 10 s-1 and 50 s-1 at 900~1200 ℃ for forged dual phase stainless steel 00Cr22Ni5Mo3N has been carried out by Gleeble 3800 simulation test machine.Test results showed that with increasing deformation ...
毛伟强 +6 more
doaj
Aging Is a Key Driver for Adult Acute Myeloid Leukemia
Aging and Cancer, EarlyView.Acute myeloid leukemia (AML) is a classical age‐related hematologic malignancy, and a key driver of AML is aging, which profoundly regulates intrinsic factors such as genomic instability, epigenetic reprogramming, and metabolic dysregulation, and alters bone marrow microenvironment.
Rong Yin, Haojian Zhang
wiley +1 more source
Teshugang, 2015 The σ-phase precipitation rule in four kinds of typical ultra-low-carbon dual phase stainless steel 00Cr21Ni2Mn5N, 00Cr22Ni5Mo3N, 00Cr25Ni7Mo3N and 00Cr27Ni7Mo5N solid-solution-treaded at 1 050 ~ 1 120 °C and aged at 500 ~ 1 100 °C and the effect of σ ...
李惠 +4 more
doaj
Dual Phase Ferrite-Martensitic Steel Micro-Alloyed with V-Nb [PDF]
Metalurgija, 2007 For low-carbon V-Nb micro-alloyed steel, dual phase ferrite-martensitic microstructures were prepared with a variable martensite fraction, which ranged from Vm 20 to 88%.
Džupon, M. +3 more
doaj
Chronobiology of Cancer: How Aging Fuels Oncogenesis at the Molecular Level
Aging and Cancer, EarlyView.This graphical abstract illustrates the key biological pathways linking aging with cancer development and progression. In the upper left, cumulative exposure to ultraviolet radiation, toxins, and reactive oxygen species (ROS) causes DNA damage and genomic instability, whereas age‐related decline in repair mechanisms, such as ATM/ATR, BER, and NER ...
Anu Singh, Aroonima Misra, Sufian Zaheer
wiley +1 more source
Constitutive model and dynamic deformation behavior of 800 MPa grade cold-rolled dual phase steel
工程科学学报, 2016 The Hopkinson experiment system was used to do the dynamic tensile experiment of 800 MPa grade cold rolled dual phase steel (DP800). The strain rate was determined as 500, 1000 and 2250 s-1 By comparing the experimental results, both the yield strength ...
CAI Heng-jun +3 more
doaj +1 more source
SPG4 and Dementia: Expanding the Clinical Spectrum
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Hereditary spastic paraplegia (HSP) is a group of disorders characterized by progressive spasticity and lower limb weakness, with mutations in SPG4/SPAST being the most common cause. Detailed studies and clinical and molecular comparisons across different populations are missing.
Emanuele Panza +19 more
wiley +1 more source