Results 41 to 50 of about 1,860 (267)

One size does not fit all: An in vitro evaluation of the effects of bezafibrate and medroxyprogesterone acetate on human SH‐SY5Y and U‐87 MG cancer cells

open access: yesFEBS Open Bio, EarlyView.
Drugs previously repurposed to target blood cancers reduced neuroblastoma and glioblastoma cell growth and viability. However, their levels of anticancer activity were different and their clinical application may be problematic due to side effects at effective doses.
Abhishek Kharawatkar   +4 more
wiley   +1 more source

Emerging insights into CC and CXC chemokines and their receptors in Mycobacterium tuberculosis infection

open access: yesFEBS Open Bio, EarlyView.
The dual roles of CC and CXC chemokines in distinguishing active, latent, and subclinical tuberculosis were reviewed, along with an evaluation of their potential as diagnostic biomarkers and therapeutic targets to advance precision medicine in tuberculosis management. The graphical abstract was generated with AI assistance (Gemini 3.0).
Xuying Yin, Dangsheng Xiao, Jiezuan Yang
wiley   +1 more source

Effect of initial microstructures on the properties of Ferrite-Martensite Dual-Phase pipeline steels with Strain-Based design

open access: yesMaterials Research, 2012
This study aims to investigate the effect of initial microstructures on the properties of ferrite-martensite dual-phase pipeline steels with strain-based design.
Yueyue Hu   +3 more
doaj  

Loss of AMBRA1 activates MAPK and angiogenesis signaling pathways in melanoma cells

open access: yesFEBS Open Bio, EarlyView.
Loss of AMBRA1 in melanoma cells activates multiple oncogenic pathways associated with tumor progression. Transcriptomic and protein network analyses revealed that AMBRA1 depletion enhances MAPK/ERK signaling, angiogenesis, TGF‐β/EMT signaling, and Wnt/axon guidance pathways.
Milad Ibrahim   +4 more
wiley   +1 more source

Aging Is a Key Driver for Adult Acute Myeloid Leukemia

open access: yesAging and Cancer, EarlyView.
Acute myeloid leukemia (AML) is a classical age‐related hematologic malignancy, and a key driver of AML is aging, which profoundly regulates intrinsic factors such as genomic instability, epigenetic reprogramming, and metabolic dysregulation, and alters bone marrow microenvironment.
Rong Yin, Haojian Zhang
wiley   +1 more source

Recent Progress in High Strength Low Carbon Steels [PDF]

open access: yesMetalurgija, 2006
Advanced High Strength (AHS) steels, among them especially Dual Phase (DP) steels, Transformation Induced Plasticity (TRIP) steels, Complex Phase (CP) steels, Partially Martensite (PM) steels, feature promising results in the field.
Zrník J., Mamuzić, I., Dobatkin, S. V.
doaj  

Damage in dual phase steels [PDF]

open access: yes, 2019
In this research, the effect of microstructural features on damage behavior isstudied with a special emphasis on evolution of plastic deformation heterogeneity in microscale. This is carried out by performing experimental and numerical work on a ferritic-martensitic DP600 steel sheet from the AHSS family.The experimental investigations are focused on ...
openaire   +1 more source

Diffusion Spectrum Imaging Maps Early Axonal Loss and a Unique Progressive Signal in Neuronal Intranuclear Inclusion Disease

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To delineate specific in vivo white matter pathology in neuronal intranuclear inclusion disease (NIID) using diffusion spectrum imaging (DSI) and define its clinical relevance. Methods DSI was performed on 42 NIID patients and 38 matched controls.
Kaiyan Jiang   +10 more
wiley   +1 more source

Friction drilling of dual phase steels

open access: yes, 2012
En este trabajo se expone un estudio del proceso de taladrado por fricción en chapas de diferentes aceros de doble fase (DP), con límites elásticos variables desde 600 hasta 800 MPa. Se realiza una evaluación de las condiciones óptimas de mecanizado en función del material y el espesor empleado, variando las velocidades de giro y los avances de ...
Nardi, D.   +2 more
openaire   +2 more sources

Vacuum carburizing of a dual phase steel.

open access: yesTransactions of the Iron and Steel Institute of Japan, 1985
A dual phase steel has been developed for which grain refining treatment subsequent to vacuum carburizing treatment at high temperature above 1000°C is not necessary. This 2wt% Si steel, which contains 0.3 wt% V and 0.04 wt% Nb, has a fine structure in both the core and case, sufficient surface hardness and excellent mechanical properties equivalent to
SHIBATA, Kimihiro   +3 more
openaire   +2 more sources

Home - About - Disclaimer - Privacy