Results 51 to 60 of about 1,860 (267)

CX3CL1 in Early Detection of Alzheimer's Disease: Plasma Dynamics Across Age and Disease Stages

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Backgrounds Alzheimer's disease (AD) is characterized by amyloid‐beta plaques, tau tangles, and neuroinflammation. C‐X3‐C motif chemokine ligand 1 (CX3CL1, also known as fractalkine), a neuroimmune chemokine implicated in AD pathogenesis, shows inconsistent alterations in plasma/serum across studies.
Ling Wang, Yujie Liu, Fei Li, Xuelin Li, Lanlan Li, Jie Zhang, Yali Xu   +6 more
wiley   +1 more source

On the damage initiation in dual phase steels

, 2021
Ziel dieser Arbeit ist die mikromechanische Untersuchung der Schädigungsinitiierung in einem Dualphasenstahl (DP800). Mikrometer kleine Druck- und Bruchmechanikproben wurden hierfür mittels fokussierter Ionenstrahlen (FIB) in einzelne Körner des Dualphasenstahls geschnitten und anschließend durch in situ im Rasterelektronenmikroskop verformt.
openaire   +2 more sources

Microstructure-based model for the stress-strain relationship of hot-rolled dual-phase steel

工程科学学报, 2015
The microstructure of hot-rolled dual-phase steel was studied by scanning electron microscopy(SEM) and transmission electron microscopy(TEM). The volume fraction of each phase in the dual-phase steel was determined by Image-Pro Plus software.
PANG Qi-hang, TANG Di, ZHAO Zheng-zhi
doaj   +1 more source

A Prospective Study of Individuals at Risk of Multiple Sclerosis Informs the Design of Primary Prevention Studies

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective In multiple sclerosis, the optimal time for deploying a therapeutic intervention is before the central nervous system is damaged; given the success of trials treating the earliest stage of MS, the radiologically isolated syndrome, developing primary prevention strategies is an important next challenge.
Amy W. Laitinen, Ceren Tozlu, Tina Roostaei, Fatoumata Diallo, Kaho Onomichi, Jiyeon Son, Zongqi Xia, Philip L. De Jager   +7 more
wiley   +1 more source

Lath martensite plasticity enabled by apparent sliding of substructure boundaries

Materials & Design, 2019
Lath martensite is widely present in advanced high strength steels as the key strengthening phase. Unexpectedly high ductility of lath martensite has been reported in the literature in both single-phase and multi-phase steels, however, without systematic
C. Du, R. Petrov, M.G.D. Geers, J.P.M. Hoefnagels   +3 more
doaj   +1 more source

Normal‐Appearing White Matter Injury Mediates Chronic Deep Venous Hypoxia and Disease Progression in Multiple Sclerosis

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To explore how cerebral hypoxia and Normal‐Appearing White Matter (NAWM) integrity affect MS lesion burden and clinical course. Methods Seventy‐nine MS patients, including 13 clinically isolated syndrome (CIS) patients and 66 relapsing–remitting multiple sclerosis (RRMS) patients, and 44 healthy controls (HCs) were recruited from ...
Xinli Wang, Huiying Wang, Zhizheng Zhuo, Ai Guo, Ke Lv, Decai Tian, Chao Chai, Yunyun Duan, Shuang Xia   +8 more
wiley   +1 more source

Multiphase Identification Through Automatic Classification from Large-Scale Nanoindentation Mapping Compared to an EBSD-Machine Learning Approach

Metals
Characterising and quantifying complex multiphase steels is a challenging and time-consuming process, which is often open to subjectivity when based on image analysis of optical metallographic or SEM images. The properties of multiphase steels are highly
Carl Slater, Bharath Bandi, Pedram Dastur, Claire Davis   +3 more
doaj   +1 more source

SPG4 and Dementia: Expanding the Clinical Spectrum

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Hereditary spastic paraplegia (HSP) is a group of disorders characterized by progressive spasticity and lower limb weakness, with mutations in SPG4/SPAST being the most common cause. Detailed studies and clinical and molecular comparisons across different populations are missing.
Emanuele Panza, Arun Meyyazhagan, Eliseo Picchi, Gustavo Ribas, Ingrid Faber, Ryosuke Miyamoto, Preethi Basavaraju, Paolo Eusebi, Haripriya Kuchi Bhotla, Mario Stasi, Fabrizio Gaudiello, Francesco Patti, Filippo Maria Santorelli, Marcondes Cavalcante França Jr, José Luiz Pedroso, Orlando Graziani Povoas Barsottini, Hélio Afonso Ghizoni Teive, Peter Henry St George‐Hyslop, Toshitaka Kawarai, Antonio Orlacchio   +19 more
wiley   +1 more source

Progress of Research and Development of Patented Technologies on Corrosion-Resistant Steels for Oil Country Tubular Goods

Teshugang, 2015
Based on published patented manufactured technologies of corrosion-resistant steels for oil country tubular goods ( OCTG) in the world from 1994, the characteristics of research and development of corrosion-resistant steels for OCTG at manufacturing ...
陈妍, 潘文龙, 何舒薇
doaj  

Dimethyl Fumarate, But Not Rituximab, Reduces Serum GFAP Levels and PIRMA in Relapsing–Remitting MS

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Serum neurofilament light chain (sNfL) and glial fibrillary acidic protein (sGFAP) levels are believed to reflect mainly acute and chronic disease processes in multiple sclerosis (MS), respectively. In this study, we investigated whether dimethyl fumarate (DMF) and rituximab (RTX) differentially affect these biomarkers.
F. Shawket, J. Lycke, J. Salzer, F. Piehl, K. Fink, N. Lange, J. Mellergård, C. Malmeström, P. Sundström, I. Erngren, A. al‐Grety, E. Freyhult, K. Kultima, J. Burman, A. Svenningsson   +14 more
wiley   +1 more source