Results 31 to 40 of about 1,866 (267)
Pediatric Blood &Cancer, EarlyView.ABSTRACT Background An earlier study on children diagnosed with acute lymphoblastic leukemia (ALL) at Moi Teaching and Referral Hospital (MTRH) in Kenya reported a low event‐free survival (EFS), excess treatment abandonment, and high induction mortality.
Gilbert Olbara +7 more
wiley +1 more source
FEBS Letters, EarlyView.Inositol pyrophosphates are energy‐rich signaling molecules that perform critical functions in cells. Three different families of phosphatases hydrolyze the β phosphate of the inositol pyrophosphate molecules: two have narrow specificities and one is promiscuous.
Ronda J. Rolfes
wiley +1 more source
HeliyonThis study aimed to fabricate a dual-phase (DP) steel with a combination of high strength-ductility-toughness by thermomechanical processing for industrial applications.
Fatemeh Khorasani +2 more
doaj +1 more source
Reconstructing enzyme evolution by protein engineering
FEBS Letters, EarlyView.Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler +2 more
wiley +1 more source
An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes
FEBS Letters, EarlyView.GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg +14 more
wiley +1 more source
Journal of Materials Research and Technology, 2019 AISI 4340 and AISI 4140 are normally used for different structural applications in quenched and tempered state due to their high strength, high abrasion and fatigue resistance but they lack toughness. Presence of dual phase microstructure such as ferrite-
Mian Muhammad Bilal +6 more
doaj +1 more source
On the law of mixtures in dual-phase steels [PDF]
Metallurgical Transactions A, 1980 The applicability of the equation of the stress in the ferrite at the ultimate tensile strain to dual-phase steels obtained by heating 1010 and 1020 grades was tested. The law of mixtures describe the tensile strength of 1010 steels provided the dislocation hardening is included.
J. Y. Koo, M. J. Young, G. Thomas
openaire +1 more source
Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
Molecular Oncology, EarlyView.This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source
Liquid biopsy‐based diagnostic evaluation of hypermethylated CpG sites for ovarian cancer diagnosis
Molecular Oncology, EarlyView.This schematic outlines the workflow from biomarker identification to duplex MethyLight assay validation for epithelial ovarian cancer diagnosis using cfDNA‐based liquid biopsy. Initial screening of hypermethylated CpG candidates (cg02957270, cg10061138 cg00480298, COL2A1) was performed in tissue using ARMS‐PCR, COBRA, qPCR and image analysis. Selected
Deepa Bisht +3 more
wiley +1 more source
Enhancement Wear Resistance of Carbon Dual Phase Steel by Cryogenic Treatment
مجلة النهرين للعلوم الهندسية, 2014 Dual phase steels containing three different amounts of martensite 21, 37 and 87 Vol. Pct. have been made from carbon steels containing 0.12, 0.33 and 0.43 wt. pct. Carbon respectively.
Abbas A. Hussein, Hussein B. Muhammad
doaj