Results 91 to 100 of about 3,008,870 (301)

Northeast Regional Meeting of the Kansas Food Safety Task Force, Olathe, Kansas, August 28, 2017.

open access: yes, 2017
PowerPoint presentation given at the 2015 Northeast Regional Meeting."The Kansas Food Safety Task Force was developed for food and feed safety and defense professionals to achieve prevention, intervention and response including the early detection ...
Kansas Food Safety Task Force.
core   +1 more source

Measuring treatment effects on dual-task performance: a framework for research and clinical practice

open access: yesFrontiers in Human Neuroscience, 2015
The relevance of dual-task walking to everyday ambulation is widely acknowledged, and numerous studies have demonstrated that dual-task interference can significantly impact recovery of functional walking in people with neurological disorders.
Prudence ePlummer   +2 more
doaj   +1 more source

Transcriptional profiling of circulating extracellular vesicles from prebiopsy prostate cancer patients

open access: yesMolecular Oncology, EarlyView.
RNA profiling of circulating extracellular vesicles (EVs) from blood samples of men undergoing prostate biopsy identifies transcripts associated with clinically significant prostate cancer. Integrative analysis with public tumor datasets links EV‐derived gene signatures to tumor stage and progression‐free survival, highlighting CASP3, XRCC2, and RIT1 ...
Stefan Werner   +14 more
wiley   +1 more source

Developmental programmes drive cellular plasticity, disease progression and therapy resistance in lung adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska   +13 more
wiley   +1 more source

Finding novel vulnerabilities of hypomorphic BRCA1 alleles

open access: yesMolecular Oncology, EarlyView.
Synthetic lethality screens performed to identify novel vulnerabilities often model complete gene loss, thereby overlooking patient‐derived hypomorphic mutations. In this study, we have performed genome‐wide CRISPR screens on BRCA1 hypomorphic mutations, showing BRCA1I26A behaves like wild‐type, while BRCA1R1699Q mimics deficiency. Furthermore, we have
Anne Schreuder   +10 more
wiley   +1 more source

Interference between gait and cognitive tasks in a rehabilitating neurological population [PDF]

open access: yes, 2000
OBJECTIVES---To quantify the extent of interference between gait and cognitive tasks after brain injury; to investigate whether such interference is common to various cognitive tasks, or confined to specific cognitive modules; to investigate whether such
Wade, D.   +4 more
core  

Miles away. Determining the extent of secondary task interference on simulated driving [PDF]

open access: yes, 2007
There is a seemingly perennial debate in the literature about the relative merits of using a secondary task as a measure of spare attentional capacity.
Young, Mark S.   +3 more
core   +1 more source

Revisiting Search Task Difficulty: Behavioral and Individual Difference Measures [PDF]

open access: yes, 2008
Search task characteristics are recognized as important factors that affect search process and its outcomes. We examine the relationships among operational measures of searcher's behavior, individual cognitive differences, subjective task difficulty and ...
Gwizdka, Jacek
core   +1 more source

Dual-task costs in speed tasks: a comparison between elite ice hockey, open-skill and closed-skill sports athletes

open access: yesFrontiers in Psychology
IntroductionIce hockey is a high pace sports game that requires players to integrate multiple skills. Players face perceptive, cognitive, and motor tasks concurrently; hence, players are regularly exposed to dual- or multi-task demands.
Mark Brinkbäumer   +3 more
doaj   +1 more source

Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization

open access: yesMolecular Oncology, EarlyView.
In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu   +13 more
wiley   +1 more source

Home - About - Disclaimer - Privacy