Results 111 to 120 of about 3,008,870 (301)
Burciu, RoxanaBackground: People often use both hands simultaneously to accomplish everyday tasks, and occasionally they do so while also attending to a cognitive task.
Crisomia, Sophia
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Illinois Terrorism Task Force- 2009 Annual Report [PDF]
, 2010 This report documents the activities and accomplishments of the Illinois Terrorism Task Force during the year 2009.not peer reviewedSubmitted by Adam Groves (agroves@illinois.edu) on 2010-03-08T17:29:44Z No. of bitstreams: 1 Illinois Terrorism Task Force-
Illinois Terrorism Task Force
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Dual-task performance in Parkinson disease (Whitfield et al., 2019)
, 2019 Purpose: Prior investigations suggest that simultaneous performance of more than 1 motor-oriented task may exacerbate speech motor deficits in individuals with Parkinson disease (PD).
Zoe Kriegel (6912609) +3 more
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Pharmacological chromatin remodeling enhances response to estrogen therapy in ER+ breast cancer
Molecular Oncology, EarlyView.Estrogen therapy elicits clinical benefit in ~ 30% of patients with endocrine‐resistant estrogen receptor (ER)‐positive breast cancer. Based on findings that ER transcriptional activation underlies response to estrogen therapy, we tested the effects of epigenetic dysregulation via pharmacological inhibition of histone deacetylases (HDACi).
Anneka L. Johnson Thomas +16 more
wiley +1 more source
Molecular Oncology, EarlyView.We show that emergence of castration‐resistant prostate (CRPC) is associated with significant upregulation of cyclins that positively regulate cyclin‐dependent kinase 2 (CDK2) and concomitant downregulation of CDK4 cyclins. This renders CRPC cells dependent on the high activity of CDK2, and CDK2 inhibitors synergistically sensitize CRPC cells to both ...
Joyeeta Chatterjee +3 more
wiley +1 more source
Benefits of dual-tasking on implicit sensorimotor adaptation
European Journal of NeuroscienceABSTRACT Attention plays a crucial role in maintaining precision and effectiveness in goal-directed actions. Although there is evidence that dividing attention across tasks impairs performance in various domains, the impact of attention on sensorimotor adaptation remains inconclusive, with some studies reporting deficits and others ...
Benjamin Miller-Mills +3 more
openaire +4 more sources
Evaluating Cognitive-Motor Interference in Multiple Sclerosis: A Technology-Based Approach
BioengineeringBackground: People with multiple sclerosis (PwMS) frequently present both cognitive and motor impairments, so it is reasonable to assume they may have difficulties in executing dual-tasks (DT). The aim of the present study is to identify novel technology-
Jessica Podda +3 more
doaj +1 more source
Unraveling the epigenetic code in cancer cell–tumor microenvironment crosstalk
Molecular Oncology, EarlyView.Epigenetic regulation is a key driver of cancer development and progression. Diverse epigenetic alterations in cancer cells and components of the tumor microenvironment (TME) orchestrate their communication through multiple mechanisms. We discuss how the epigenetic code coordinates bidirectional cancer cell–TME crosstalk to promote cancer progression ...
Ji Hoon Park, Mi‐Young Kim
wiley +1 more source
, 2015 This archived document is maintained by the Oregon State Library as part of the Oregon Documents Depository Program. It is for informational purposes and may not be suitable for legal purposes.Title from PDF cover (viewed on January 25, 2016)."...
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Molecular Oncology, EarlyView.Loss of NAPRT promotes lung tumor initiation and growth through a noncanonical mechanism, independent of its role in NAD+ biosynthesis. Mechanistically, NAPRT depletion activates the mTORC2‐driven AKT/β‐catenin signaling axis to enhance clonogenic and invasive phenotypes. Furthermore, lung‐specific Naprt deletion significantly increases tumor burden in
Myung Joon Oh +11 more
wiley +1 more source