Results 121 to 130 of about 3,008,870 (301)

Regulation of the lncRNA NEAT1 by p53‐ΔNp63 crosstalk modulates the DNA damage response and therapeutic efficacy in HNSCC

Molecular Oncology, EarlyView.
In head and neck squamous cell carcinoma (HNSCC) p53 and p63 exert opposite roles on the transcription regulation of the lncRNA NEAT1. Under basal conditions, p53 levels are low and p63 represses NEAT1 expression. Upon genotoxic stress, p53 is rapidly induced, displacing p63 from the NEAT1 promoter leading to NEAT1 transcriptional activation and ...
Sara De Domenico, Veronica La Banca, Silvia D'Amico, Stefano Scalera, Sara Nicolai, Angelo Peschiaroli   +5 more
wiley   +1 more source

Model of Care for People with Mental Disorder and Co-existing Substance Use Disorder (Dual Diagnosis)

, 2023
This Model of Care has been developed in partnership with HSE Social Inclusion, HSE Health and Wellbeing and the National Office of Suicide Prevention and in collaboration with voluntary bodies including Sec.39 agencies.
National Working Group for Dual Diagnosis
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Investigating underlying brain structures and influence of mild and subjective cognitive impairment on dual-task performance in people with Parkinson’s disease

Scientific Reports
Cognitive impairment can affect dual-task abilities in Parkinson’s disease (PD), but it remains unclear whether this is also driven by gray matter alterations across different cognitive classifications.
Franziska Albrecht, Hanna Johansson, Urban Ekman, Konstantinos Poulakis, Lucian Bezuidenhout, Joana B. Pereira, Erika Franzén   +6 more
doaj   +1 more source

Paclitaxel induces NM2‐dependent cellular contraction through GEF‐H1 dissociation from microtubules and RhoA/ROCK activation in cancer cells

Molecular Oncology, EarlyView.
Taxanes are widely used chemotherapeutics whose effects on cellular mechanics remain poorly understood. We show that paclitaxel induces rapid cellular contraction by promoting GEF‐H1 dissociation from microtubules and non‐muscle myosin II activation through RhoA/ROCK.
Gloria Asensio‐Juárez, Rafael Pérez‐Díaz, Hugo Ramos‐Solano, Marina Garrido‐Casado, Vanessa C. Talayero, Miguel Vicente‐Manzanares   +5 more
wiley   +1 more source

Draft task force report

, 2014
This archived document is maintained by the Oregon State Library as part of the Oregon Documents Depository Program. It is for informational purposes and may not be suitable for legal purposes.Title from PDF cover (viewed on November 19, 2014)"Draft for

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Illinois Terrorism Task Force- 2006 Annual Report [PDF]

, 2007
This report documents the activities and accomplishments of the Illinois Terrorism Task Force during the year 2006.Submitted by Adam Groves (agroves@fsi.uiuc.edu) on 2008-07-03T15:30:00Z No.
Illinois Terrorism Task Force
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p190A/ARHGAP35 and p190B/ARHGAP5 proteins in endometrial cancer: a novel cancer‐relevant paralog interplay

Molecular Oncology, EarlyView.
This study identifies ARHGAP5, in addition to the frequently mutated ARHGAP35, as significantly mutated in endometrial cancer. Mutations in both genes co‐occur and are associated with their correlated downregulation. Functional CRISPR studies show that both paralogs regulate similar pathways, including actin cytoskeleton organization.
Mathilde Pinault, Capucine Heraud, Mélissa Correia de Oliveira, Véronique Neaud, Valérie Valesco, Valérie Prouzet‐Mauleon, Béatrice Turcq, Jean‐William Dupuy, Anne‐Aurélie Raymond, Sabrina Croce, Frédéric Saltel, Valérie Lagrée, Violaine Moreau   +12 more
wiley   +1 more source

Walking Stroop carpet: an innovative dual-task concept for detecting cognitive impairment

, 2013
A Perrochon,1,2,5 G Kemoun,1,2 E Watelain,3,4 A Berthoz51ISIS, Research Institute on Handicap and Aging, Paris; 2Université de Poitiers, Laboratoire Mobilité, Vieillissement et Exercice (MOVE), EA 6314, 3Université de Valenciennes ...
Kemoun G, Perrochon A, Watelain E, Berthoz A   +3 more
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Illinois Terrorism Task Force- 2005 Annual Report [PDF]

, 2006
This report documents the activities and accomplishments of the Illinois Terrorism Task Force during the year 2005.Submitted by Adam Groves (agroves@fsi.uiuc.edu) on 2006-09-22T16:03:49Z No.
Illinois Terrorism Task Force
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Dual-task exercise protects healthy older adults against in-creased risk for dementia: A controlled trial

Baltic Journal of Health and Physical Activity
Background: Functionality in aging is closely linked to the ability to divide attention during multitasking activities, which are essential for activities of daily life.
Helen Tatiane PONTES, João BENTO-TORRES, Naina Yuki Vieira JARDIM, Victor Oliveira DA COSTA, Josilayne Patricia Ramos CARVALHO, Cristovam Wanderley PICANÇO-DINIZ, Natáli Valim Oliver BENTO-TORRES   +6 more
doaj   +1 more source