Results 61 to 70 of about 3,008,870 (301)
Application and Research of Dual-Task Paradigms in Central Nervous System Diseases
康复学报, 2022 The ability to perform two or more tasks simultaneously in activities of daily living is essential. The cognitive-motor dual-task paradigm refers to the simultaneous performance of a cognitive task and a motor task, where the cognitive task can be ...
LI Qinyi +9 more
doaj
Epigenetic reprogramming of lineage switching in cancer
FEBS Letters, EarlyView.Cancer cells rarely commit to a single identity. Epigenetic mechanisms and tumor microenvironment cues push epithelial cells toward flexible, hybrid states that can shift into mesenchymal, neuroendocrine, or stem‐like fates, driving metastasis, drug resistance, and tumor heterogeneity. Targeting the epigenetic regulators behind these transitions, using
Ezgi Boyvatlı +4 more
wiley +1 more source
Dual Task Interference in Parkinson's Disease
European Neurological Review, 2009 Performing two tasks simultaneously (dual task performance) is a frequent activity in human life. Patients with Parkinson’s disease (PD) commonly have more difficulty performing dual tasks than healthy people. To date, research on the mechanisms of dual task interference in PD remains sparse.
Mark Hallett, Tao Wu
openaire +1 more source
Testing-the-limits of optimizing dual-task performance in younger and older adults
Frontiers in Human Neuroscience, 2012 Impaired dual-task performance in younger and older adults can be improved with practice. Optimal conditions even allow for a (near) elimination of this impairment in younger adults.
Tilo eStrobach +4 more
doaj +1 more source
Golgi enzymes are retrieved from the plasma membrane to the trans‐Golgi network
FEBS Letters, EarlyView.Golgi enzymes are traditionally considered resident proteins retained within the Golgi apparatus. Here, we demonstrate that a subset transiently reaches the cell surface and is subsequently retrieved to the trans‐Golgi network via retrograde transport. Using a nanobody‐based toolkit, we uncover a dynamic trafficking cycle of several Golgi enzymes.
Dominik P. Buser, Tina Junne
wiley +1 more source
Effects of Gait and Cognitive Task Difficulty on Cognitive-Motor Interference in Aging
Journal of Aging Research, 2012 Although gait-related dual-task interference in aging is well established, the effect of gait and cognitive task difficulty on dual-task interference is poorly understood.
Prudence Plummer-D'Amato +5 more
doaj +1 more source
Emerging experimental and computational methods for studying redox‐regulated structural transitions
FEBS Letters, EarlyView.Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass +2 more
wiley +1 more source
Dual-task costs while turning.
, 2020 Dual-task costs (DTC) of HD participants during turns; Results of a two-tailed independent sample t-test indicating significant cognitive interference observed for turn duration (p = 0.013) (A) and number of steps to turn (p = 0.029) (B) in HD compared ...
Joan A. O’Keefe (8259825) +5 more
core +1 more source
SportsObjective: This study investigated gait and cognitive dual-task costs under a dual-task paradigm that was more challenging than the traditional tasks used in research. Methods: A total of 43 18–25-year-old male and female student athletes were recruited (
Gabriel Lavoie +4 more
doaj +1 more source
Feasibility of Dual-Task Gait Training for Community-Dwelling Adults after Stroke: A Case Series
Stroke Research and Treatment, 2014 This case series explored the feasibility and efficacy of cognitive-motor dual-task gait training in community-dwelling adults within 12 months of stroke. A secondary aim was to assess transfer of training to different dual-task combinations.
Prudence Plummer +4 more
doaj +1 more source