Results 51 to 60 of about 3,008,870 (301)

Evaluating Dual Task Neurological Costs with Functional Near-Infrared Spectroscopy: A Preliminary Report in Healthy Athletes

open access: yesJournal of Integrative Neuroscience, 2023
Background: Dual task assessments, which simultaneously challenge and assess cognitive and motor performance, have been used to improve the assessment of athletes with sports-related concussions (SRC). Our lab created a Dual Task Screen (DTS) to evaluate
Jaclyn A Stephens   +2 more
doaj   +1 more source

Identification of a Shiga toxin A‐derived peptide internalized into Gb3 receptor‐bearing cells via interaction with the Shiga toxin B subunit

open access: yesFEBS Letters, EarlyView.
The process of internalization of the Shiga toxin A subunit via formation of a complex with the Shiga toxin B subunit, which specifically binds to the Gb3 receptor. The peptide is designed to act as a carrier of drugs into cancer cells. Here, we explored the potential of peptides derived from the catalytic A subunit of Shiga toxin (STxA) to be drug ...
Giulia Opassi   +6 more
wiley   +1 more source

An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes

open access: yesFEBS Letters, EarlyView.
GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg   +14 more
wiley   +1 more source

Dual-to-single-task-ratio in reaction times to peripheral stimuli in the dual Tracking Task: score at T-pre (DSR-all pre) vs. difference score (DSR-all diff = T-pre—T-post: positive value means improvement).

open access: yes, 2016
Dual-to-single-task-ratio in reaction times to peripheral stimuli in the dual Tracking Task: score at T-pre (DSR-all pre) vs. difference score (DSR-all diff = T-pre—T-post: positive value means improvement).
Gera A. de Haan (783875)   +4 more
core   +1 more source

Resilience of perceptual metacognition in a dual-task paradigm [PDF]

open access: yesPsychonomic Bulletin & Review, 2019
When people do multiple tasks at the same time, it is often found that their performance is worse relative to when they do those same tasks in isolation. However, one aspect that has received little empirical attention, is whether the ability to monitor and evaluate one’s task performance is also affected by multitasking.
Konishi, Mahiko   +4 more
openaire   +4 more sources

Comparative effects of arithmetic, speech, and motor dual-task walking on gait in stroke survivors: a cross-sectional study

open access: yesFrontiers in Human Neuroscience
BackgroundThe application of dual-task walking paradigms for gait assessment in stroke patients is critical, where varying concurrent tasks may elicit distinct gait patterns of dual-task interference.
Xueyi Zhang   +8 more
doaj   +1 more source

Cognitive and motor dual task gait training exerted specific training effects on dual task gait performance in individuals with Parkinson's disease: A randomized controlled pilot study.

open access: yesPLoS ONE, 2019
Gait impairments in Parkinson's disease (PD) are aggravated under dual task conditions. Providing effective training to enhance different dual task gait performance is important for PD rehabilitation.
Yea-Ru Yang   +4 more
doaj   +1 more source

Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics

open access: yesFEBS Letters, EarlyView.
Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt   +8 more
wiley   +1 more source

Dual-task assessment of a sporting skill: influence of task complexity and relationship with competitive performances

open access: yes, 2012
We investigated the effect of increases in task complexity on the dual-task draw-and-pass performance of professional rugby league players. Moreover, we determined the relationship between dual-task draw-and-pass proficiency measured in isolation and ...
Gabbett, Tim J., Abernethy, Bruce
core   +1 more source

Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation

open access: yesFEBS Letters, EarlyView.
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang   +2 more
wiley   +1 more source

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