Results 51 to 60 of about 6,006,276 (250)

Directed evolution of enzymes at the crossroads of tradition and innovation

FEBS Open Bio, EarlyView.
An iterative cycle of data‐driven enzyme optimization comprising four stages: genetic diversification of a template enzyme, expression of protein variants, high‐throughput evaluation, and machine‐learning‐guided redesign of the next variant library.
Maria Tomkova, Andrej Mirossay, Erik Sedlak   +2 more
wiley   +1 more source

Evaluating Cognitive-Motor Interference in Multiple Sclerosis: A Technology-Based Approach

Bioengineering
Background: People with multiple sclerosis (PwMS) frequently present both cognitive and motor impairments, so it is reasonable to assume they may have difficulties in executing dual-tasks (DT). The aim of the present study is to identify novel technology-
Jessica Podda, Ludovico Pedullà, Giampaolo Brichetto, Andrea Tacchino   +3 more
doaj   +1 more source

Cognitive and motor dual task gait training improve dual task gait performance after stroke - A randomized controlled pilot trial

Scientific Reports, 2017
This study investigated effects of cognitive and motor dual task gait training on dual task gait performance in stroke. Participants (n = 28) were randomly assigned to cognitive dual task gait training (CDTT), motor dual task gait training (MDTT), or ...
Yan-Ci Liu, Yea-Ru Yang, Yun-An Tsai, Ray-Yau Wang   +3 more
doaj   +1 more source

Task matters: an investigation on the effect of different secondary tasks on dual-task gait in older adults

BMC Geriatrics, 2021
Background Dual-task gait performance declines as humans age, leading to increased fall risk among older adults. It is unclear whether different secondary cognitive tasks mediate age-related decline in dual-task gait. This study aimed to examine how type
Hui-Ting Goh, Miranda Pearce, Asha Vas
doaj   +1 more source

MagmaFlow: A desktop platform for artificial intelligence‐driven expression analysis

FEBS Open Bio, EarlyView.
MagmaFlow is a free, no‐code platform for gene expression analysis. It generates interactive volcano plots, links genes to literature, pathways, and diseases, prioritizes candidates using millions of publications, identifies affected biological processes, builds network diagrams, and exports publication‐ready figures and reports for macOS and Windows ...
Carlos E. Buss, Ao Li, Eduardo H. Gilglioni, Mayank Bansal, Sumeet Pal Singh, Latifa Bakiri, Alessandra K. Cardozo, Esteban N. Gurzov   +7 more
wiley   +1 more source

Inhibitory control in prospective memory: An event related potential comparison of task-switch and dual task processing

, 2021
This study cross-validates reported changes in behavioural and event-related potential (ERP) correlates of prospective memory (PM) inhibitory control performance applying different PM response selection demands (Bisiacchi et al., 2009). Participants were
Hockey, A, A. Hockey, Cutmore, T, T. Cutmore   +3 more
core   +1 more source

Effect of Static Balance Ability on Dual-Task Costs Under Different Walking TaskInterventions in Chinese Older Adults

Xiehe Yixue Zazhi
ObjectiveTo compare gait parameters during single-task and dual-task walking in older adults, and to examine differences in dual-task costs between individuals with high versus low balance abilities under different task conditions.MethodsFrom November to
WANG Chenglong, NIE Mingjian, XIAO Chenhui, WU Yini, WANG Jingjing   +4 more
doaj   +1 more source

A new flow chip in combination with multiphoton microscopy as a protocol for longitudinal 3D imaging of tissue calcification under shear stress

FEBS Open Bio, EarlyView.
Miniaturized flow chip platform enabling continuous perfusion and longitudinal multiphoton 3D imaging of vascular smooth muscle cell constructs under physiological flow. Brightfield imaging guides region selection, while CellTracker Green and mRuby‐labeled fetuin‐A visualize cells and mineral deposition, respectively. Magnesium supplementation markedly
Vytautas Kučikas, Aaron D. Morgan, Ignas Čiurlionis, Christian Böhm, Stefan Jockenhövel, Willi Jahnen‐Dechent, Marc A. M. J. van Zandvoort   +6 more
wiley   +1 more source

Dual-task costs in speed tasks: a comparison between elite ice hockey, open-skill and closed-skill sports athletes

Frontiers in Psychology
IntroductionIce hockey is a high pace sports game that requires players to integrate multiple skills. Players face perceptive, cognitive, and motor tasks concurrently; hence, players are regularly exposed to dual- or multi-task demands.
Mark Brinkbäumer, Christian Kupper, Lukas Reichert, Karen Zentgraf   +3 more
doaj   +1 more source

Dose‐dependent hepatotoxicity of hydrogen peroxide in HepG2 cells and its modulation by CYP450 induction

FEBS Open Bio, EarlyView.
NMR metabolomics revealed concentration‐dependent metabolic perturbations in HepG2 cells exposed to H2O2. Rifampicin pretreatment enhanced metabolic competence, attenuated toxin‐induced alterations and produced metabolite profiles more consistent with human liver physiology, supporting the use of CYP450‐induced HepG2 models for improved in vitro ...
Maren Jinks, Garth L. Maker, Emily C. Davies, Berin A. Boughton, Samantha Lodge   +4 more
wiley   +1 more source