Results 201 to 210 of about 1,805,046 (316)

Malignant transformation of host stromal fibroblasts derived from the bone marrow traced in a dual-color fluorescence xenograft tumor model

, 2015
Xingliang Dai, Hua Chen, Yanming Chen, Jinding Wu, Haiyang Wang, Jia Shi, Xifeng Fei, Zhimin Wang, Aidong Wang, Jun Dong, Qing Lan, Qiang Huang   +11 more
openalex   +2 more sources

Cotargeting TREM2 and IL2 pathways triggers multipronged anticancer immunity

Molecular Oncology, EarlyView.
Von Locquenghien et al. report that MiTE‐144, a triggering receptor expressed on myeloid cells 2 (TREM2) blocking antibody fused to interleukin‐2 (IL2) variant with tumour microenvironment restricted activation, demonstrates superior anticancer efficiency in a preclinical setting.
Isaure Vanmeerbeek, Jenny Sprooten, Abhishek D. Garg   +2 more
wiley   +1 more source

Federal Look-Alike Plan Termination Policy and Dual-Eligible Enrollment in Integrated Care Programs.

JAMA Health Forum
Ma Y, Roberts ET, Phelan J, Johnston KJ, Orav EJ, Meara ER, Figueroa JF.   +6 more
europepmc   +1 more source

Risk of Hospitalized COVID-19 in COPD: Single-Inhaler Triple Versus Dual Bronchodilator Therapy. [PDF]

Pharmacoepidemiol Drug Saf
Galmiche S, Dell'Aniello S, Suissa S.
europepmc   +1 more source

Actin dynamics controlled by IqgC, a RasGAP at the crossroads between the IQGAP and fungal GAP1 families

FEBS Open Bio, EarlyView.
IqgC is a RasGAP from Dictyostelium discoideum. IqgC binds RasG via its RasGAP domain and deactivates it on macroendocytic cups, thereby suppressing the uptake of fluid and particles. IqgC has a positive effect on cell‐substratum adhesion, and its RGCt domain is required for recruitment to ventral foci.
Vedrana Filić, Darija Putar, Lucija Mijanović, Igor Weber   +3 more
wiley   +1 more source

Combination therapy with TNF inhibitors plus biologics targeting type 2 inflammatory conditions in patients with rheumatoid arthritis: a case series. [PDF]

Rheumatol Adv Pract
Ocon AJ, Abdalla A, Vengilote R, Ramsey A, Mustafa SS.   +4 more
europepmc   +1 more source

Short vs prolonged dual antiplatelet treatment upon endovascular stenting of peripheral arteries

, 2017
Mariya Kronlage, Maximilian Wassmann, Britta Vogel, Oliver J. Müller, Erwin Blessing, Hugo A. Katus, Christian Erbel   +6 more
openalex   +2 more sources

Interplay between RNA‐protein interactions and RNA structures in gene regulation

FEBS Open Bio, EarlyView.
Methodological advances in mapping transcriptome‐wide RNA‐protein interactions and RNA structures have started to uncover the potential of RNP conformations in gene regulation. Competing RNA–RNA, RNA‐protein and protein–protein interactions shape the compaction and function of RNPs throughout their lifetime and may provide novel therapeutic targets in ...
Jenni Rapakko, Mauro Scaravilli, Minna‐Liisa Änkö   +2 more
wiley   +1 more source

A meta-analysis of the effects of dual-task training on cognitive function in stroke patients. [PDF]

Front Neurol
Shi R, Li W, Liu X, Sun Z, Ge X, Lv P, Yin Y.   +6 more
europepmc   +1 more source

Lactoferrin treatment activates acetylcholinesterase, decreasing acetylcholine levels in non‐small cell lung cancer (NSCLC) cell culture supernatants, inhibiting cell survival

FEBS Open Bio, EarlyView.
Representation of the suggested mode of action of lactoferrin (Lf) in nonsmall cell lung cancer (NSCLC) A549 cells. Lf induces activation of caspase‐3 by activating p53 and AChE leading to decreased ACh concentrations. In turn, ACh signaling leads to activation of VEGF and AKT and blocking of caspase‐3.
Stuti Goel, Caroline Wozniak, Aya Sabri, Ben Haddad, Brooke Lopo, Alvaro Cobos, Sarah Sarofim, Jeffrey Guthrie, Deborah Heyl, Hedeel Guy Evans   +9 more
wiley   +1 more source