Subcutaneous implantation of murine Panc02 pancreatic cancer cells depleted of sST2, a soluble decoy receptor for the proinflammatory interleukin‐33 (IL‐33), leads to a decreased number of GLUT4‐positive cancer‐associated adipocytes, reduced levels of the anti‐inflammatory molecule adiponectin, increased phosphorylation of IκBα, elevated Cxcl3 ...
Miho Akimoto+5 more
wiley +1 more source
Fourteen-day vonoprazan-amoxicillin dual therapy versus 14-day bismuth-based quadruple therapy for <i>Helicobacter pylori</i> treatment: a randomized clinical trial. [PDF]
Zhang JY+6 more
europepmc +1 more source
Sphingoid base structures, the sphingolipid backbones, vary among species. We established yeast cells in which the native sphingoid base was replaced with plant‐type bases containing cis or trans double bonds. This is, to our knowledge, the first eukaryotic model mostly composed of sphingolipids containing cis‐unsaturated sphingoid base, providing a ...
Takashi Higuchi+5 more
wiley +1 more source
Can adults automatically process and translate between numerical representations? [PDF]
Xenidou-Dervou I+4 more
europepmc +1 more source
Most autophagic cell death studies lack evidence of causality
Of 104 studies claiming autophagic cell death (ACD), only 13 demonstrated both causality and exclusion of apoptosis to confirm true ACD. Most studies relied on correlation‐level data or measured autophagy in isolation, revealing pervasive methodological shortcomings.
Ali Burak Özkaya, Yasmin Ghaseminejad
wiley +1 more source
Leveraging a Dual-Focused Growth Mindset to Boost Employee Resilience and Work Well-Being: Evidence From a Two-Wave Survey and an Intervention Study. [PDF]
Siu OL, Yang Y, Li A, Wang H, Ng TK.
europepmc +1 more source
Mechanical axial instability of segmental pedicle screw instrumentation for adolescent idiopathic scoliosis: a retrospective cohort study of tulip screw versus dual locking cup instrumentation. [PDF]
Frantzén A+4 more
europepmc +1 more source
ABSTRACT Objective The characteristics and utility of composite progression independent of relapse activity (cPIRA; worsening on the Expanded Disability Status Scale [EDSS], or 9‐Hole Peg Test, or Timed 25‐Foot Walk Test) were evaluated as an endpoint in relapsing multiple sclerosis (RMS) trials using the ENSEMBLE (NCT03085810) and pooled OPERA I/II ...
Ludwig Kappos+11 more
wiley +1 more source
Finotonlimab (PD-1 inhibitor) plus bevacizumab (bevacizumab biosimilar) as first-tier therapy for late-stage hepatocellular carcinoma: a randomized phase 2/3 trial. [PDF]
Zhao C+59 more
europepmc +1 more source