Results 71 to 80 of about 19,547 (317)

Strawberry Notch 1 Acts as a Transcriptional Regulator Driving Oncogenic Programs in Liver Carcinogenesis

Advanced Science, EarlyView.
This study reports that SBNO1 protein is upregulated in several cancer entities. SBNO1 protein interacts with the basal transcription factor TFIID via TAF4, enabling its recruitment to transcription start sites and the modulation of target gene expression.
Sarah Fritzsche, Raisatun Nisa Sugiyanto, Kira Gür, Alina Krumme, Maxime Le Marois, Angelika Fraas, Aslihan Inal, Mario Huerta, Vanessa Henriques, Eva Eiteneuer, Thomas Albrecht, Alphonse Charbel, Michael T. Dill, Carsten Sticht, Carolina De La Torre, Stefan Pusch, Arianeb Mehrabi, Kai Breuhahn, Junfang Ji, Peter Schirmacher, Benjamin Goeppert, Stephanie Roessler   +21 more
wiley   +1 more source

Practical Evaluation of Loss Reduction in Isolated Series Resonant Converter with Fixed Frequency Modulation

Energies, 2022
Nowadays, power converters with reduced cost, compact size and high efficiency are evolving to overcome the emergent challenges of renewable energy integrations.
Danish Khan, Pengfei Hu, Muhammad Waseem, Muhammad Yasir Ali Khan, Mustafa Tahir, Andres Annuk   +5 more
doaj   +1 more source

Evaluation of isolated DC/DC converter topologies for future HVDC aerospace microgrids [PDF]

, 2017
High performance power conversion equipment is currently gaining an increasing interest for aircraft applications. In particular, isolated bidirectional DC/DC converters are often proposed for modern HVDC aircraft distribution systems. For such reason an
Costabeber, Alessando, Galea, Michael, Linglin, Chen, Tarisciotti, Luca, Walker, Adam   +4 more
core   +2 more sources

Gallium‐Doped MXene Nanozymes Protect Liver Through Multi‐Death Pathway Blockade and Hepatocyte Regeneration

Advanced Science, EarlyView.
This study develops gallium‐doped V2C MXene nanozymes (Ga‐V2C) to treat acetaminophen‐induced liver injury through multi‐death pathway blockade and hepatocyte regeneration. Unlike conventional single‐target therapies like N‐acetylcysteine, Ga‐V2C nanozymes enable oxidative stress suppression, apoptosis, and ferroptosis inhibition, and enhanced ...
Xiaopeng Cai, Jingwen Deng, Liqing Wang, Junjie Su, Dongyi Xian, Yilang Yan, Xinyu Yang, Chuanbin Wu, Tingting Peng, Yuan Ding, Guilan Quan, Weilin Wang, Min Zhou, Chao Lu   +13 more
wiley   +1 more source

Modular multi-level converter solid-state transformer based on the clamped switch pair integrated submodule

电力工程技术
Modular multi-level converter based solid-state transformer (MMC-SST) has gained wide attention in AC-DC hybrid distribution network due to the availability of ports with multiple voltage levels and voltage patterns. Dual active bridge (DAB)-type MMC-SST
GUO Wanxin, SUN Yichao, YAN Yinyu, ZHANG Yifan   +3 more
doaj   +1 more source

rWTC‐MBTA Vaccine, Alone and Enhanced with Anti‐PD1, Elicits Immune Responses against CNS and Peripheral B‐Cell Lymphoma

Advanced Science, EarlyView.
An autologous whole‐tumor‐cell vaccine (rWTC‐MBTA) is evaluated in murine CNS lymphoma. Subcutaneous vaccination activates dendritic cells, broadens T‐cell priming, and drives lymphocyte trafficking to brain tumors, producing durable tumor control. Longitudinal bioluminescence and adoptive‐transfer assays verify CNS engagement. Combination with anti‐PD‐
Yaping Zhang, Juan Ye, Mitchell Sun, Samik Chakraborty, Alex Valenzuela, Shuran Chen, Qingfeng Xue, Wenyu Shi, Karel Pacak, Herui Wang, Zhengping Zhuang   +10 more
wiley   +1 more source

DC-Link Voltage Coordinated-Proportional Control for Cascaded Converter with Zero Steady-State Error and Reduced System Type [PDF]

, 2016
copyright 2015 IEEE. Personal use of this material is permitted. Permission from IEEE must be obtained for all other users, including reprinting/ republishing this material for advertising or promotional purposes, creating new collective works for resale
Chen, Zhe, Deng, Fujin, Hu, Yanting, Loh, Poh C., Tian, Yanjun   +4 more
core   +1 more source

Small Nucleolar RNA Snord17 Promotes Self‐Renewal of Intestinal Stem Cells through Yy2 mRNA Export and Tead4 Activation

Advanced Science, EarlyView.
Snord17, through interaction with Thoc3, promotes nuclear export and translation of Yy2 mRNA in Snord17+/+ ISCs. The Yy2 protein subsequently binds the Tead4 promoter to promote its transcription, activating Hippo signaling, which is essential for ISC maintenance.
Peikang Zhang, Yuwei Xu, Yufei Lan, Zhen Xiong, Zhibin Yi, Runyuan Wu, Cunzhen Li, Ying Du, Hui Guo, Yingchi Yang, Zusen Fan   +10 more
wiley   +1 more source

Impedance modeling and stability analysis of dual active bridge converter with LC input filter

CES Transactions on Electrical Machines and Systems, 2018
The dual active bridge (DAB) converter is gaining more and more attention in various applications such as energy storage systems, electric vehicles and smart grids.
Fan Feng, Xin Zhang, Fanfan Lin, Hoay Beng Gooi   +3 more
doaj   +1 more source

Innovative heat sink design for enhanced cooling efficiency in Dual Active Bridge (DAB) topology

Journal of Physics: Conference Series
Abstract After in-depth research and analysis, aiming at the heat generation mechanism and limitations of the current heat dissipation method, this paper proposes an innovative heat dissipation design scheme. By optimizing the structural design of the heat sink, the heat dissipation surface area is increased, thus achieving more ...
Chenghong Liu, Zhuowei Xu, Donghao Han, Jian Ma   +3 more
openaire   +1 more source