Results 81 to 90 of about 4,734,173 (343)

Dimethyl fumarate combined with cisplatin at subcytotoxic doses sensitizes cervical cancer toward ferroptosis and apoptosis through GSH restriction and p53 (re)activation

open access: yesMolecular Oncology, EarlyView.
Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano   +6 more
wiley   +1 more source

Structural and Parametric Optimization of Steam Boiler Injection Regulators

open access: yesИзвестия высших учебных заведений и энергетических объединенний СНГ: Энергетика
Steam temperature control significantly affects the efficiency, reliability and durability of steam boilers. In the article, special attention is paid to substantiating the relevance of a significant increase in the efficiency of steam boiler injection ...
G. T. Kulakov, N. V. Voyush
doaj   +1 more source

Targeted modulation of IGFL2‐AS1 reveals its translational potential in cervical adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
Cervical adenocarcinoma patients face worse outcomes than squamous cell carcinoma counterparts despite similar treatment. The identification of IGFL2‐AS1's differential expression provides a molecular basis for distinguishing these histotypes, paving the way for personalized therapies and improved survival in vulnerable populations globally.
Ricardo Cesar Cintra   +6 more
wiley   +1 more source

Dual Channel Attention Networks

open access: yesJournal of Physics: Conference Series, 2020
Abstract Channel attention is currently widely used in Computer Vision. Most existing channel attention networks are proposed based on Squeeze-and-Excitation Networks (SE- Net),which can obtain excellent performance by designing complex structures, however, they also has more additional network parameters and higher floating point ...
Jingchen Bian, Yugui Liu
openaire   +1 more source

On privacy amplification, lossy compression, and their duality to channel coding

open access: yes, 2018
We examine the task of privacy amplification from information-theoretic and coding-theoretic points of view. In the former, we give a one-shot characterization of the optimal rate of privacy amplification against classical adversaries in terms of the ...
Renes, Joseph M.
core   +1 more source

EDNRB‐dependent endothelin signaling reduces proliferation and promotes proneural‐to‐mesenchymal transition in gliomas

open access: yesMolecular Oncology, EarlyView.
Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau   +36 more
wiley   +1 more source

Boundary Holographic Witten Diagrams

open access: yes, 2017
In this paper we discuss geodesic Witten diagrams in generic holographic conformal field theories with boundary or defect. Boundary CFTs allow two different decompositions of two-point functions into conformal blocks: boundary channel and ambient channel.
Karch, Andreas, Sato, Yoshiki
core   +1 more source

Heterozygous loss‐of‐function alleles associate the conserved 3′‐5′ exoribonuclease EXOSC10 with hypersensitivity to the anticancer drug 5‐fluorouracil

open access: yesMolecular Oncology, EarlyView.
EXOSC10, an essential nuclear RNA exosome‐associated 3′‐5′ exoribonuclease, is inhibited by the anticancer drug 5‐fluorouracil (5‐FU), and EXOSC10 depletion increases 5‐FU sensitivity. The colon‐cancer variant EXOSC10S402T, located in a proteolysis motif, is stable and nuclear but nonfunctional in vivo.
Radhika Sain   +10 more
wiley   +1 more source

Dual channel routing scheme in ad hoc networks

open access: yesTongxin xuebao, 2006
By improving the capacity of ad hoc networks by using multiple channel interfaces,a dual channel routing(DCR)scheme was introduced that proactively maintains all nodes’ location information based on periodic exchanges of location information in one ...
WANG Qing-hui1   +2 more
doaj  

Insulation for cryogenic tanks has reduced thickness and weight [PDF]

open access: yes, 1966
Dual seal insulation, consisting of an inner layer of sealed-cell Mylar honeycomb core and an outer helium purge channel of fiber glass reinforced phenolic honeycomb core, is used as a thin, lightweight insulation for external surfaces of cryogenic ...
Dumire, P. E.   +3 more
core   +1 more source

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