Results 41 to 50 of about 974,940 (289)
In the present work, the chemical reactivity of indaziflam N-[(1R,2S)-2,3-dihydro-2,6-dimethyl-1H-inden-1 yl]-6-[(1R)-1-16 fluoroethyl]-1,3,5-triazine-2,4-diamine so called indaziflam (IND) and its metabolites: triazine indanone (ITI), indaziflam ...
Luis Humberto Mendoza-Huizar +3 more
doaj +1 more source
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura +2 more
wiley +1 more source
Achieving sustainable green hydrogen economy requires overcoming the challenges associated with hydrogen production and utilization, one of them being the sluggish kinetics of hydrogen evolution and oxidation reactions (HER/HOR) in alkaline media ...
Mohammed Amine Hammouali +6 more
doaj +1 more source
Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz +11 more
wiley +1 more source
In this chapter the properties of descriptor revision, as defined in Chapter 4, are further explored. Several alternative selection mechanisms are presented, and the properties of the resulting operations are investigated.
Sven Ove Hansson, Hansson, Sven Ove,
core +1 more source
On computing least order fault detectors using rational nullspace bases [PDF]
We propose a numerically reliable computational approach to design least order fault detectors using descriptor system techniques. This approach is based on a new numerically stable algorithm to compute least order rational nullspace bases of rational ...
A. Varga, Varga, Andras
core +1 more source
An isoform of 14‐3‐3 protein regulates transbilayer lipid movement at the plasma membrane
Loss of 14‐3‐3ζ in CHO cells confers resistance to exogenous phosphatidylserine (PS) and impairs endocytosis‐independent inward flip‐flop of fluorescent PS at the plasma membrane. RNAi‐mediated knockdown reproduces this defect, while no additive effect is seen in ATP11C‐deficient cells.
Akiko Yamaji‐Hasegawa +3 more
wiley +1 more source
Dual Descriptor also reveals the Janus-Faced Behaviour of Diiodine [PDF]
The diiodine molecule as Janus-faced ligand was evidenced by Rogachev and Hoffmann [A.Y. Rogachev et al., JACS , 2013, 135 , 3262] through an exhaustive investigation based on the Molecular Orbital Theory (MOT), Natural Bond Orbital (NBO), and Energy ...
openaire +1 more source
In local change, the operation ∘ is specific for the original belief set K. Formally it is a function that takes us from a descriptor Ψ to an element K∘ Ψ of the outcome set X (the set of belief sets that are potential outcomes of belief change). It only
Sven Ove Hansson, Hansson, Sven Ove,
core +1 more source
Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley +1 more source

