Results 81 to 90 of about 211,702 (296)

Degradation mechanism of the von Willebrand factor A2 domain by nattokinase

open access: yesFEBS Letters, EarlyView.
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto   +3 more
wiley   +1 more source

Modulation of Homer1 EVH1 domain internal dynamics by putative autism‐associated mutations

open access: yesFEBS Letters, EarlyView.
The putative autism‐associated M65I and S97L variants of the EVH1 domain of the postsynaptic scaffold protein Homer1 do not exhibit substantial changes in their overall structure or partner binding. Both of them, but especially the M65I variant, show altered internal dynamics relative to the wild‐type domain on the μs‐ms timescale, indicated by the ...
Fanni Farkas   +6 more
wiley   +1 more source

Multivariate structural time series models with dual cycles : implications for measurement of output gap and potential growth [PDF]

open access: yes
Structural time series models applied to the factor inputs of a production function often lead to small output gaps and consequently to erratic measures of potential growth.
Philippe Moës
core  

Building the Dual Earner/Dual Career Society: Policy Developments in Europe, CES Working Paper, no. 82, 2002 [PDF]

open access: yes, 2002
A new model of work and family life is emerging out of contemporary debates on social citizenship and the characteristics of the“woman-friendly” welfare state.
Meyers, Marcia K., Gornick, Janet C.,
core  

Design optimization of a novel dual-skewed Halbach-array double-sided axial flux permanent magnet motor for electric vehicles

open access: yesScientific Reports
This paper introduces the design and analysis of a novel dual-skewed Halbach-array permanent magnet (PM) double-sided axial flux (TORUS) motor developed for electric vehicle applications.
Phuson Srikhumphun   +4 more
doaj   +1 more source

An unexpected alternative viologen electron mediator site in tungsten‐containing formate dehydrogenase

open access: yesFEBS Letters, EarlyView.
An unexpected alternative interaction site for ethyl viologen was identified in formate dehydrogenase 1 from Methylorubrum extorquens. Combined mutagenesis, kinetic analysis, and docking revealed that aromatic residues near an iron–sulfur cluster enable flavin mononucleotide‐independent electron transfer, offering a framework for engineering improved ...
Eleni G. Poloniataki, Yong Hwan Kim
wiley   +1 more source

The gender gap in workplace authority in Sweden 1968-2000 – a family affair? [PDF]

open access: yes
We assess whether the gender gap in authority in Sweden has changed during the period 1968–2000, and investigate to what extent family factors are responsible for this gap.
Gähler, Michael, Bygren, Magnus
core  

A Multi-sensor Gait Dataset Collected Under Non-standardized Dual-Task Conditions

open access: yesScientific Data
Non-standardized dual-tasks have recently gained attention in gait analysis. Currently, there is a lack of publicly available non-standardized dual-task gait datasets collected with multiple sensors.
Yuanyuan Liao   +4 more
doaj   +1 more source

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

open access: yesFEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa   +2 more
wiley   +1 more source

Emigration and wage inequality in a dual economy [PDF]

open access: yes
We examine the effect of emigration of skilled and unskilled labor on pre-existing wage gap between the skilled-unskilled labor. The results by Marjit and Kar (2005) will be confirmed also in a dual economy setup.International factor mobility, Wage ...
Shigemi Yabuuchi
core  

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