Results 31 to 40 of about 1,895,744 (248)

Effect of Dual Task Training on Balance and Functional Mobility in Children with Cerebral Palsy

open access: yesReabilitacijos Mokslai: Slauga, Kineziterapija, Ergoterapija, 2020
Research background. It was found that dual task training improves functional abilities in subjects with neurological disorders, however it is not known how dual task training affects balance and functional mobility in children with cerebral palsy (CP).
Karolina Kvedaravičienė, Rima Solianik
doaj   +1 more source

Degradation mechanism of the von Willebrand factor A2 domain by nattokinase

open access: yesFEBS Letters, EarlyView.
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto   +3 more
wiley   +1 more source

Surgical Management of Bilateral Trapeziometacarpal Arthritis: Suspension Arthroplasty and Dual Mobility Prosthesis in the Same Patient, Treated at the Same Time

open access: yesSurgeries
Background: Trapeziometacarpal osteoarthritis (TMC OA) is a prevalent degenerative disorder that causes considerable pain and functional limitations, especially in older individuals, whose ideal treatment is still debated in the literature.
Matteo Guzzini   +5 more
doaj   +1 more source

Charge-carrier velocity distributions in high-mobility polymer dual-gate thin-film transistors

open access: yes, 2012
We report charge-carrier velocity distributions in high-mobility polymer thin-film transistors (PTFTs) employing a dual-gate configuration. Our time-domain measurements of dual-gate PTFTs indicate higher effective mobility as well as fewer low-velocity ...
Sonar, P., Ha, T. J., Dodabalapur, A.
core   +1 more source

Design and analysis strategies for robust microbiome ageing research

open access: yesFEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik   +5 more
wiley   +1 more source

Investigating transcription factor dynamics in health and disease using FRAP

open access: yesFEBS Letters, EarlyView.
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj   +3 more
wiley   +1 more source

Use of a modular hip dual-mobility articulation in patients with high risk of dislocation: a relatively small-sized acetabulum in Asian patients may limit its use

open access: yesArthroplasty, 2021
Background Dual-mobility hip component is widely used in Europe and North America, because it effectively reduces hip dislocation in primary and revision total hip arthroplasties.
Ping Keung Chan   +9 more
doaj   +1 more source

Using the cell phone while standing or walking affects balance and mobility in people with Parkinson's disease

open access: yesArquivos de Neuro-Psiquiatria, 2023
Background Cell phones are part of peoples' lives. The literature indicates risks when cell phones are used during a secondary motor task. Studies addressing this topic in people with Parkinson's disease are still scarce.
Tayla Borges Lino   +5 more
doaj   +1 more source

Model of Care for People with Mental Disorder and Co-existing Substance Use Disorder (Dual Diagnosis)

open access: yes, 2023
This Model of Care has been developed in partnership with HSE Social Inclusion, HSE Health and Wellbeing and the National Office of Suicide Prevention and in collaboration with voluntary bodies including Sec.39 agencies.
National Working Group for Dual Diagnosis
core  

Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics

open access: yesFEBS Letters, EarlyView.
Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt   +8 more
wiley   +1 more source

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