Results 41 to 50 of about 118,554 (256)

Comparison of dual-mobility cup and unipolar cup for prevention of dislocation after revision total hip arthroplasty

Acta Orthopaedica, 2017
Background and purpose — Revision total hip arthroplasty (THA) is associated with higher dislocation rates than primary THA. We compared the risk of dislocation within 6 months and all-cause re-revision during the whole study period using either the dual-
Amanda Inez Gonzalez, Placido Bartolone, Anne Lubbeke, Elise Dupuis Lozeron, Robin Peter, Pierre Hoffmeyer, Panayiotis Christofilopoulos   +6 more
doaj   +1 more source

Effects of two 24-week multimodal exercise programs on reaction time, mobility, and dual-task performance in community-dwelling older adults at risk of falling: a randomized controlled trial

BMC Public Health, 2021
Background Falls in older adults are considered a major public health problem. Declines in cognitive and physical functions, as measured by parameters including reaction time, mobility, and dual-task performance, have been reported to be important risk ...
Hugo Rosado, Jorge Bravo, Armando Raimundo, Joana Carvalho, José Marmeleira, Catarina Pereira   +5 more
doaj   +1 more source

Dual mobility prosthesis in Hip Arthroplasty

International journal of health sciences, 2022
Background: With the increase in the number of total hip arthroplasty performed in the next decades to reduce or prevent medical and mechanical complications such as post operative THA instability Dual mobility was introduced as an alternative to standard sockets to reduce the risk of THA dislocation post operatively.(1) Aim of the work: to evaluate ...
Elamir A. Mohei Eldin, Mahmoud M. Said, Tharwat Abd El Rahman, Abdel Hamed Abdelaziz, Mahmoud Zayad, Mohamed Ramadan Elfishawy   +5 more
openaire   +1 more source

CDK11 inhibition induces cytoplasmic p21WAF1 splice variant by p53 stabilisation and SF3B1 inactivation

Molecular Oncology, EarlyView.
CDK11 inhibition stabilises the tumour suppressor p53 and triggers the production of an alternative p21WAF1 splice variant p21L, through the inactivation of the spliceosomal protein SF3B1. Unlike the canonical p21WAF1 protein, p21L is localised in the cytoplasm and has reduced cell cycle‐blocking activity.
Radovan Krejcir, Lukasz Arcimowicz, Lucia Martinkova, Vaclav Hrabal, Filip Zavadil Kokas, Tomas Henek, Martina Kucerikova, Ondrej Bonczek, Pavlina Zatloukalova, Lenka Hernychova, Philip J. Coates, Borivoj Vojtesek, David P. Lane   +12 more
wiley   +1 more source

Canted seating of the Stryker Modular Dual Mobility liner within a Trident hemispherical acetabular shell

Arthroplasty Today, 2016
A 75-year-old woman who suffered a left femoral neck fracture underwent a left total hip arthroplasty using a Stryker Trident (Kalamazoo, MI) hemispherical acetabular shell and Modular Dual Mobility (MDM) metal liner.
Scott M. Eskildsen, MD, Erik C. Olsson, MD, Daniel J. Del Gaizo, MD   +2 more
doaj   +1 more source

Intraprosthetic dislocation of dual-mobility total hip arthroplasty implant

Radiology Case Reports, 2023
Dual-mobility total hip arthroplasties were developed to decrease the risk of dislocation and instability seen with traditional fixed-bearing total hip arthroplasties.
Perry Veras, BS, Patrick Gidley, MD, Nisha R. Patel, MD, Caleb Bhatnagar, BS, Rami El-Baba, DO, Emad Allam, MD   +5 more
doaj   +1 more source

Cis‐regulatory and long noncoding RNA alterations in breast cancer – current insights, biomarker utility, and the critical need for functional validation

Molecular Oncology, EarlyView.
The noncoding region of the genome plays a key role in regulating gene expression, and mutations within these regions are capable of altering it. Researchers have identified multiple functional noncoding mutations associated with increased cancer risk in the genome of breast cancer patients.
Arnau Cuy Saqués, Aracele Martinez‐Mendez, John Crown, Alex Eustace   +3 more
wiley   +1 more source

Dual-Mobility Cups in Patients Undergoing Primary Total Hip Arthroplasty with Prior Lumbar Spine Fusion: A Systematic Review

Surgeries
Spine and hip abnormalities frequently occur together in most of the orthopedic population; therefore, both of these abnormalities impact the outcomes of the modalities that are being used. Few studies have reported reduced dislocation and revision rates
Tariq Ziad Issa, Adam Pearl, Emelia Moore, Hannan Ahmad Maqsood, Khaled J. Saleh   +4 more
doaj   +1 more source

ATF4‐mediated stress response as a therapeutic vulnerability in chordoma

Molecular Oncology, EarlyView.
We screened 5 chordoma cell lines against 100+ inhibitors of epigenetic and metabolic pathways and kinases and identified halofuginone, a tRNA synthetase inhibitor. Mechanistically halofuginone induces an integrated stress response, with eIF2alpha phosphorylation, activation of ATF4 and its target genes CHOP, ASNS, INHBE leading to cell death ...
Lucia Cottone, James Dunford, Eleanor Calcutt, Vicki Gamble, Filiz Senbabaoglu Aksu, Lorena Ligammari, Georgina Wherry, Giorgia Gaeta, John C. Christianson, Adrienne M. Flanagan, Udo Oppermann, Adam P. Cribbs   +11 more
wiley   +1 more source

Infrared laser sampling of low volumes combined with shotgun lipidomics reveals lipid markers in palatine tonsil carcinoma

Molecular Oncology, EarlyView.
Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff, Manuela Moritz, Dennis Eggert, Anna Worthmann, Joerg Heeren, Henrike Zech, Till S. Clauditz, Waldemar Wilczak, Hartmut Schlüter, Christian S. Betz, Arne Böttcher, Jan Hahn   +11 more
wiley   +1 more source