Results 181 to 190 of about 1,204,012 (303)

Conjugated oligoelectrolytes overcome cancer drug resistance by dual-mode lysosomal membrane disruption. [PDF]

Cancer Drug Resist
Wang L, Mao Y, Dong Y, Tan M, Wang X, Liu Z, Nie C, Xing S, Li M, Yuan H, Wang B.   +10 more
europepmc   +1 more source

Acute caffeine treatment protects the developing retina from ischemia‐induced cell death

FEBS Open Bio, EarlyView.
Caffeine reduces cell death in the developing retina under ischemia (OGD). This effect does not involve BDNF upregulation or antioxidant pathways (NRF2/VEGF). Neuroprotection occurs mainly through adenosine A2A receptor antagonism, decreasing glutamate release and excitotoxicity, highlighting caffeine's potential as an acute neuroprotective agent in ...
Amanda Alves Nascimento, Danniel Pereira‐Figueiredo, Gabriella Grossi de Lima Dias, Gabriel Ferreira dos Santos, Mariana Rodrigues Pereira, Rafael Brito, Karin C Calaza   +6 more
wiley   +1 more source

Deep learning-enhanced dual-mode multiplexed optical sensor for point-of-care diagnostics of cardiovascular diseases. [PDF]

Light Sci Appl
Han GR, Eryilmaz M, Goncharov A, Li Y, Ye S, Tomoeda A, Ngo E, Scussat M, Wang X, Ji Z, Zhang M, Hsu JJ, Garner OB, Di Carlo D, Ozcan A.   +14 more
europepmc   +1 more source

Pharmacological inhibition of the PERK pathway modulates hepatocellular carcinoma growth and immune signaling

FEBS Open Bio, EarlyView.
Pharmacological inhibition of PERK in a DEN‐induced mouse model of liver cancer does not reduce tumor burden but alters cellular stress signaling. Despite blocking PERK activity, downstream stress responses, including CHOP expression, remain active, suggesting compensatory mechanisms within the unfolded protein response that may influence tumor ...
Ada Lerma‐Clavero, Maria Kopsida, Nathalie Arendt, Hans Lennernäs, Markus Sjöblom, Femke Heindryckx   +5 more
wiley   +1 more source

IRS-Assisted Dual-Mode Relay-Based Adaptive Transmission. [PDF]

Sensors (Basel)
Wang D, Xu Y, Gao Z, Ding H, Zhu S, Li Z.   +5 more
europepmc   +1 more source

RoundMi: A quantitative method to analyze mitochondrial morphology in mitotic cells

FEBS Open Bio, EarlyView.
RoundMi is a workflow for rapid analysis of mitochondrial morphology in mitotic cells. By combining adaptive preprocessing with automated segmentation and quantification, it enables accurate measurements from single focal plane images, reducing acquisition time and computational demands while remaining compatible with high‐throughput fixed and live ...
Elmira Parvindokht Bararpour, Christine Volmert, Valentina Piano   +2 more
wiley   +1 more source

6/7 Modes spéciaux : les “dual modes”

Oxymag, 2016
Bula, Flore, Büsch, Justine, Kern, Laeticia, Grant, Kathleen, Thévoz, David, Piquilloud, Lise   +5 more
openaire   +2 more sources

Scalable Mie-Silk textile for dual-mode personal cooling indoors and outdoors. [PDF]

Sci Adv
Wang Y, Wu XE, Lu H, Qi L, Zhou Y, Wu S, Jin J, Li D, Bi P, Zou M, Lin S, Liang H, Zhu M, Gan L, Fan W, Dai X, Zhang Y.   +16 more
europepmc   +1 more source

One size does not fit all: An in vitro evaluation of the effects of bezafibrate and medroxyprogesterone acetate on human SH‐SY5Y and U‐87 MG cancer cells

FEBS Open Bio, EarlyView.
Drugs previously repurposed to target blood cancers reduced neuroblastoma and glioblastoma cell growth and viability. However, their levels of anticancer activity were different and their clinical application may be problematic due to side effects at effective doses.
Abhishek Kharawatkar, Francesco Michelangeli, Farhat Latif Khanim, Christopher Martin Bunce, William Eustace Basil Johnson   +4 more
wiley   +1 more source

An astragalus polysaccharide-loaded hydrogel dressing enhances diabetic wound healing via dual-mode electrical stimulation. [PDF]

Bioact Mater
Chen Z, Huo X, Wu Z, Ji G, Liu B, Tian H, Tang T, Deng J, Zhao Q, Li F.   +9 more
europepmc   +1 more source