Results 91 to 100 of about 4,249,593 (344)
Real‐time assay of ribonucleotide reductase activity with a fluorescent RNA aptamer
FEBS Letters, EarlyView.Ribonucleotide reductases (RNR) synthesize DNA building blocks de novo, making them crucial in DNA replication and drug targeting. FLARE introduces the first single‐tube real‐time coupled RNR assay, which enables isothermal tracking of RNR activity at nanomolar enzyme levels and allows the reconstruction of allosteric regulatory patterns and rapid ...
Jacopo De Capitani +4 more
wiley +1 more source
On a New Generalization of Pell Hybrid Numbers
Annales Mathematicae SilesianaeIn this paper, we define and study a new one-parameter generalization of the Pell hybrid numbers. Based on the definition of r-Pell numbers, we define the r-Pell hybrid numbers.
Bród Dorota +2 more
doaj +1 more source
IMPLEMENTATION OF THE ALGEBRA OF HYPERDUAL NUMBERS IN NEURAL NETWORKS
Scientific Journal of Astana IT UniversityFor the numerical solution of problems arising in various fields of mathematics and mechanics, it is often necessary to determine the values of derivatives included in the model.
Bimurat Sagindykov, Zhanar Bimurat
doaj +1 more source
The role of histone modifications in transcription regulation upon DNA damage
FEBS Letters, EarlyView.This review discusses the critical role of histone modifications in regulating gene expression during the DNA damage response (DDR). By modulating chromatin structure and recruiting repair factors, these post‐translational modifications fine‐tune transcriptional programmes to maintain genomic stability.
Angelina Job Kolady, Siyao Wang
wiley +1 more source
Dual quaternion representation of points, lines and planes
Discrete and Continuous Models and Applied Computational ScienceBackground. The bulk of the work on dual quaternions is devoted to their application to describe helical motion. Little attention is paid to the representation of points, lines, and planes (primitives) using them. Purpose. It is necessary to consistently
Migran N. Gevorkyan +4 more
doaj +1 more source
On a new one-parameter generalization of dual-complex Jacobsthal numbers [PDF]
, 2021 Dorota Bród +2 more
openalex +1 more source
FEBS Letters, EarlyView.Multidrug transporters BpeB and BpeF from the Gram‐negative pathogen Burkholderia pseudomallei have a hydrophilic patch in their substrate‐binding pocket. Drug susceptibility tests and growth curve analyses using an Escherichia coli recombinant expression system revealed that the hydrophilic patches of BpeB and BpeF are involved in the substrate ...
Ui Okada, Satoshi Murakami
wiley +1 more source
Erlangen Program at Large-1: Geometry of Invariants
Symmetry, Integrability and Geometry: Methods and Applications, 2010 This paper presents geometrical foundation for a systematic treatment of three main (elliptic, parabolic and hyperbolic) types of analytic function theories based on the representation theory of SL_2(R) group. We describe here geometries of corresponding
Vladimir V. Kisil
doaj +1 more source
Function‐driven design of a surrogate interleukin‐2 receptor ligand
FEBS Letters, EarlyView.Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang +9 more
wiley +1 more source
On dual hyperbolic generalized Fibonacci numbers
Indian Journal of Pure and Applied Mathematics, 2019 In this paper, we introduce the generalized dual hyperbolic Fibonacci numbers. As special cases, we deal with dual hyperbolic Fibonacci and dual hyperbolic Lucas numbers. We present Binet's formulas, generating functions and the summation formulas for these numbers. Moreover, we give Catalan's, Cassini's, d'Ocagne's, Gelin-Cesàro's, Melham's
openaire +4 more sources