Results 81 to 90 of about 414,156 (258)

Phosphoinositides and inositol phosphates as molecular glues

open access: yesFEBS Letters, EarlyView.
Inositol phosphates (IPs) and phosphoinositides (PIPs) regulate diverse eukaryotic processes. Beyond recruiting signaling proteins or acting as structural cofactors, recent studies suggest they mediate protein–protein interactions as natural molecular glues.
Aleshia Seaton‐Terry   +9 more
wiley   +1 more source

The Regularity of Functions on Dual Split Quaternions in Clifford Analysis

open access: yesAbstract and Applied Analysis, 2014
This paper shows some properties of dual split quaternion numbers and expressions of power series in dual split quaternions and provides differential operators in dual split quaternions and a dual split regular function on Ω⊂ℂ2×ℂ2 that has a dual split ...
Ji Eun Kim, Kwang Ho Shon
doaj   +1 more source

Three phosphatase families form a community: The phosphohydrolases that act upon inositol pyrophosphates

open access: yesFEBS Letters, EarlyView.
Inositol pyrophosphates are energy‐rich signaling molecules that perform critical functions in cells. Three different families of phosphatases hydrolyze the β phosphate of the inositol pyrophosphate molecules: two have narrow specificities and one is promiscuous.
Ronda J. Rolfes
wiley   +1 more source

Exploiting Air-Pressure to Map Floorplans on Point Sets

open access: yesJournal of Graph Algorithms and Applications, 2014
We prove a conjecture of Ackerman, Barequet and Pinter. Every floorplan with n internal segments can be embedded on every set of n points in generic position.
Stefan Felsner
doaj   +1 more source

On dual hyperbolic generalized Fibonacci numbers

open access: yesIndian Journal of Pure and Applied Mathematics, 2019
In this paper, we introduce the generalized dual hyperbolic Fibonacci numbers. As special cases, we deal with dual hyperbolic Fibonacci and dual hyperbolic Lucas numbers. We present Binet's formulas, generating functions and the summation formulas for these numbers. Moreover, we give Catalan's, Cassini's, d'Ocagne's, Gelin-Cesàro's, Melham's
openaire   +4 more sources

Design and analysis strategies for robust microbiome ageing research

open access: yesFEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik   +5 more
wiley   +1 more source

Methods for Multiple Attribute Decision Making with Interval-Valued Pythagorean Fuzzy Information

open access: yesMathematics, 2018
Interval-valued Pythagorean fuzzy numbers (IVPFNs) can easily describe the incomplete and indeterminate information by degrees of membership and non-membership, and the Hamy mean (HM) operator and dual HM (DHM) operators are a good tool for dealing with ...
Zengxian Li, Guiwu Wei, Hui Gao
doaj   +1 more source

Reconstructing enzyme evolution by protein engineering

open access: yesFEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler   +2 more
wiley   +1 more source

Identification of a Shiga toxin A‐derived peptide internalized into Gb3 receptor‐bearing cells via interaction with the Shiga toxin B subunit

open access: yesFEBS Letters, EarlyView.
The process of internalization of the Shiga toxin A subunit via formation of a complex with the Shiga toxin B subunit, which specifically binds to the Gb3 receptor. The peptide is designed to act as a carrier of drugs into cancer cells. Here, we explored the potential of peptides derived from the catalytic A subunit of Shiga toxin (STxA) to be drug ...
Giulia Opassi   +6 more
wiley   +1 more source

Dual Quaternion Functions and Its Applications

open access: yesJournal of Applied Mathematics, 2013
A dual quaternion is associated with two quaternions that have basis elements e0, e1, e2, e3, and ε. Dual numbers are often written in the form z=ζ+εζ*, where ε is the dual identity and has the properties ε2=0  (ε≠0).
Su Jin Lim, Kwang Ho Shon
doaj   +1 more source

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