Results 71 to 80 of about 1,544,790 (278)

Sequence determinants of RNA G‐quadruplex unfolding by Arg‐rich regions

open access: yesFEBS Letters, EarlyView.
We show that Arg‐rich peptides selectively unfold RNA G‐quadruplexes, but not RNA stem‐loops or DNA/RNA duplexes. This length‐dependent activity is inhibited by acidic residues and is conserved among SR and SR‐related proteins (SRSF1, SRSF3, SRSF9, U1‐70K, and U2AF1).
Naiduwadura Ivon Upekala De Silva   +10 more
wiley   +1 more source

Erlangen Program at Large-1: Geometry of Invariants

open access: yesSymmetry, Integrability and Geometry: Methods and Applications, 2010
This paper presents geometrical foundation for a systematic treatment of three main (elliptic, parabolic and hyperbolic) types of analytic function theories based on the representation theory of SL_2(R) group. We describe here geometries of corresponding
Vladimir V. Kisil
doaj   +1 more source

Hyper-Dual Leonardo Numbers

open access: yes, 2022
In the present paper, the hyper-dual Leonardo numbers will be introduced with the use of Leonardo numbers. Some algebraic properties of these numbers such as recurrence relation, generating function, Catalan’s and Cassini’s identity, Binet’s formula, sum formulas will also be obtained.
ÖZKALDI KARAKUŞ, Sıddıka   +2 more
openaire   +2 more sources

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

open access: yesFEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee   +3 more
wiley   +1 more source

Topological or rotational non-Abelian gauge fields from Einstein-Skyrme holography

open access: yesJournal of High Energy Physics, 2021
We report analytically known states at non-zero temperature which may serve as a powerful tool to reveal common topological and thermodynamic properties of systems ranging from the QCD phase diagram to topological phase transitions in condensed matter ...
Casey Cartwright   +2 more
doaj   +1 more source

Tau acetylation at K331 has limited impact on tau pathology in vivo

open access: yesFEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto   +3 more
wiley   +1 more source

A methionine‐lined active site governs carbocation stabilization and product specificity in a bacterial terpene synthase

open access: yesFEBS Letters, EarlyView.
This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel   +13 more
wiley   +1 more source

Models for Multiple Attribute Decision-Making with Dual Generalized Single-Valued Neutrosophic Bonferroni Mean Operators

open access: yesAlgorithms, 2018
In this article, we expand the dual generalized weighted BM (DGWBM) and dual generalized weighted geometric Bonferroni mean (DGWGBM) operator with single valued neutrosophic numbers (SVNNs) to propose the dual generalized single-valued neutrosophic ...
Jie Wang, Xiyue Tang, Guiwu Wei
doaj   +1 more source

Absence of Non-Trivial Supersymmetries and Grassmann Numbers in Physical State Spaces [PDF]

open access: yes, 2014
This paper reviews the well-known fact that nilpotent Hermitian operators on physical state spaces are zero, thereby indicating that the supersymmetries and "Grassmann numbers" are also zero on these spaces.
Kihara, Hironobu
core   +1 more source

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

open access: yesFEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura   +2 more
wiley   +1 more source

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