Results 161 to 170 of about 776,276 (326)
Loss of the frequently mutated chromatin remodeler ARID1A, a subunit of the SWI/SNF cBAF complex, results in less open chromatin, alternative splicing, and the failure to stop cells from progressing through the cell cycle after DNA damage in bladder (cancer) cells. Created in BioRender. Epigenetic regulators, such as the SWI/SNF complex, with important
Rebecca M. Schlösser+11 more
wiley +1 more source
Jumping numbers and ordered tree structures on the dual graph
Eero Hyry, Tarmo Järvilehto
openalex +2 more sources
On Dual $k-$ Pell Bicomplex Numbers and Some Identities Including Them
Serpil Halıcı, Şule Çürük
openalex +2 more sources
Germline variants in CDKN2A wild‐type melanoma prone families
Among melanoma‐prone families, wild‐type for CDKN2A and CDK4, some have pathogenic variants in genes not usually linked to melanoma. Furthermore, rare XP‐related variants and variants in MC1R are enriched in such families. Germline pathogenic variants in CDKN2A are well established as an underlying cause of familial malignant melanoma. While pathogenic
Gjertrud T. Iversen+5 more
wiley +1 more source
Statistical convergence of sequences of dual numbers
Nur GUuml NCAN Ayşe
openalex +1 more source
Chronic TGF‐β exposure drives epithelial HCC cells from a senescent state to a TGF‐β resistant mesenchymal phenotype. This transition is characterized by the loss of Smad3‐mediated signaling, escape from senescence, enhanced invasiveness and metastatic potential, and upregulation of key resistance modulators such as MARK1 and GRM8, ultimately promoting
Minenur Kalyoncu+11 more
wiley +1 more source
We identified adaptor protein ShcD as upregulated in triple‐negative breast cancer and found its expression to be correlated with reduced patient survival and increased invasion in cell models. Using a proteomic screen, we identified novel ShcD binding partners involved in EGFR signaling pathways.
Hayley R. Lau+11 more
wiley +1 more source
Fourier-Mukai functors and perfect complexes on dual numbers
Francesco Amodeo, Riccardo Moschetti
openalex +2 more sources
On dual bicomplex numbers and their some algebraic properties
The object of this work is to contribute to the development of bicomplex numbers. For this purpose, in this study we firstly introduced bicomplex numbers with coefficients from complex Fibonacci sequence. And then, using Babadag's work[1], we examined the dual form of the newly defined numbers.
Halıcı, Serpil, Çürük, Şule
openaire +2 more sources
Dual targeting of AKT and mTOR using MK2206 and RAD001 reduces tumor burden in an intracardiac colon cancer circulating tumor cell xenotransplantation model. Analysis of AKT isoform‐specific knockdowns in CTC‐MCC‐41 reveals differentially regulated proteins and phospho‐proteins by liquid chromatography coupled mass spectrometry. Circulating tumor cells
Daniel J. Smit+19 more
wiley +1 more source