Results 51 to 60 of about 776,276 (326)
FEBS Letters, EarlyView.Metabolic dysfunction‐associated steatotic liver disease (MASLD) affects nearly one‐third of the global population and poses a significant risk of progression to cirrhosis or liver cancer. Here, we discuss the roles of hepatic dendritic cell subtypes in MASLD, highlighting their distinct contributions to disease initiation and progression, and their ...
Camilla Klaimi +3 more
wiley +1 more source
On Leonardo Pisano Hybrinomials
Mathematics, 2021 A generalization of complex, dual, and hyperbolic numbers has recently been defined as hybrid numbers. In this study, using the Leonardo Pisano numbers and hybrid numbers we investigate Leonardo Pisano polynomials and hybrinomials.
Ferhat Kürüz +2 more
doaj +1 more source
Insights into PI3K/AKT signaling in B cell development and chronic lymphocytic leukemia
FEBS Letters, EarlyView.This Review explores how the phosphoinositide 3‐kinase and protein kinase B pathway shapes B cell development and drives chronic lymphocytic leukemia, a common blood cancer. It examines how signaling levels affect disease progression, addresses treatment challenges, and introduces novel experimental strategies to improve therapies and patient outcomes.
Maike Buchner
wiley +1 more source
FEBS Letters, EarlyView.In modular polyketide synthases, the dehydratase (DH) domain catalyzes the dehydration reaction of the β‐hydroxyacyl unit attached to the cognate acyl carrier protein (ACP) domain. However, it is unclear how DH interacts with ACP during the reaction. In this study, we identified DH–ACP interface residues, providing the first detailed insights into DH ...
Kaede Kotagiri +8 more
wiley +1 more source
Application of Generalized (Hyper-) Dual Numbers in Equation of State Modeling
Frontiers in Chemical Engineering, 2021 The calculation of derivatives is ubiquitous in science and engineering. In thermodynamics, in particular, state properties can be expressed as derivatives of thermodynamic potentials. The manual differentiation of complex models can be tedious and error-
Philipp Rehner, Gernot Bauer
doaj +1 more source
Functional variation among LPMOs revealed by the inhibitory effects of cyanide and buffer ions
FEBS Letters, EarlyView.This study addresses the inhibition of lytic polysaccharide monooxygenases (LPMOs) by cyanide and explains how and why the magnitude of observed inhibitory effects depends on the way LPMO reactions are setup and on the type of LPMO. Enzymes known as lytic polysaccharide monooxygenases (LPMOs) are mono‐copper polysaccharide‐degrading peroxygenases that ...
Ole Golten +10 more
wiley +1 more source
Integrated Dynamics of Space Rigid-Flex Combination System with Time-Varying Configuration
International Journal of Aerospace Engineering, 2023 Dual numbers were applied to the dynamics of a rigid-flexible combination system (RFCS) with time-varying configuration in this paper. The six-dimensional spinor form of the motion of flexible modules, including the dual vector, dual momentum, dual ...
Yaen Xie +4 more
doaj +1 more source
The Pontryagin dual of the multiplicative group of positive rational numbers
AIMS Mathematics, 2023 The Pontryagin dual of the multiplicative group of positive rational numbers is constructed. Then we study its topological generators and representations.
Chaochao Sun, Yuanbo Liu
doaj +1 more source
Standard Dual Quaternion Optimization and Its Applications in Hand-Eye Calibration and SLAM [PDF]
arXiv, 2022 Several common dual quaternion functions, such as the power function, the magnitude function, the $2$-norm function and the $k$th largest eigenvalue of a dual quaternion Hermitian matrix, are standard dual quaternion functions, i.e., the standard parts of their function values depend upon only the standard parts of their dual quaternion variables ...
arxiv
Characteristics of the Kelch domain containing (KLHDC) subfamily and relationships with diseases
FEBS Letters, EarlyView.The Kelch protein superfamily includes 63 members, with the KLHDC subfamily having 10 proteins. While their functions are not fully understood, recent advances in KLHDC2's structure and role in protein degradation have highlighted its potential for drug development, especially in PROTAC therapies.
Courtney Pilcher +6 more
wiley +1 more source