Results 121 to 130 of about 1,636 (288)

Proteasome inhibitor, ixazomib prevents topoisomerase‐I degradation and reverses irinotecan resistance in colorectal cancer

open access: yesMolecular Oncology, EarlyView.
Ixazomib inhibits proteasome‐mediated degradation of topoisomerase I induced by irinotecan, thereby restoring drug sensitivity and promoting tumor cell death in colorectal cancer. Irinotecan, a topoisomerase I (topoI) inhibitor, is widely used for colorectal cancer, but resistance remains a major clinical challenge.
Yuho Ebata   +10 more
wiley   +1 more source

Dual quaternion representation of points, lines and planes

open access: yesDiscrete and Continuous Models and Applied Computational Science
Background. The bulk of the work on dual quaternions is devoted to their application to describe helical motion. Little attention is paid to the representation of points, lines, and planes (primitives) using them. Purpose. It is necessary to consistently
Migran N. Gevorkyan   +4 more
doaj   +1 more source

Estimation of Rotation and Translation Simultaneously Using Dual Quaternion

open access: yes, 2007
本文使用雙四元數來取代表示物體轉移的旋轉矩陣 與移動向量 ,雙四元數最大的好處就是可以同時處理物體的轉動與移動,並且以雙四元數的連續乘積對一種特別的向量-雙向量做運算來表示一連串轉移。雙四元數的求解過程是將轉移前與轉移後的待測物上取出相對的雙向量,比對相對的雙向量來找出表示待測物轉移的雙四元數,又稱之為雙四元數的封閉式解法(Closed-Form Solution)。目前的標準作法是將雙向量與雙四元數之間的關係經過推導後以矩陣運算與SVD(Singular Value Decomposition)來解得[
黃博彥, Huang, Po-Yen
core  

DNA methylation and expression of MAPRE3 affect overall survival of early‐stage non‐small cell lung cancer patients

open access: yesMolecular Oncology, EarlyView.
Both cg12821679MAPRE3 methylation and MAPRE3 expression are significantly associated with overall survival (OS) of non‐small cell lung cancer. Meanwhile, MAPRE3 expression significantly modified the effect of smoking cessation on OS. Smoking cessation benefits OS merely for patients with high MAPRE3 expression.
Chao Chen   +14 more
wiley   +1 more source

A Mirsky-Type Unitarily Invariant Norm Inequality for Dual Quaternion Matrices and Its Applications

open access: yes
In this paper, we present a Mirsky-type unitarily invariant norm inequality for dual quaternion matrices, which can be regarded as a singular value perturbation theorem for dual quaternion matrices.
Ping Zhong, Jin Zhong
core   +1 more source

Circulating tumor cell viability during and after radiotherapy mirrors treatment response in cancer patients

open access: yesMolecular Oncology, EarlyView.
Radiotherapy (RT) response depends on the DNA repair capacity of tumor and host cells. We show that circulating tumor cell (CTC) counts and apoptosis rates before and after RT predict treatment response and outcome, which can be accessed via easily accessible liquid biopsy approaches. Created in BioRender. Wikman, H.
Yvonne Goy   +10 more
wiley   +1 more source

Developmental programmes drive cellular plasticity, disease progression and therapy resistance in lung adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska   +13 more
wiley   +1 more source

Six-Dimensional Atmosphere Entry Guidance based on Dual Quaternion

open access: yes, 2021
This paper investigates the six-degree-of-freedom (6-DoF) entry guidance problem for the Human Mars exploration mission. For the Human-scale entry, powered descent, and landing mission, it is required to use aerodynamic forces to decelerate the vehicle ...
Pei, Chaoying   +4 more
core  

Flow Enabled Target Capture Halbach‐based magnetic enrichment increases circulating tumor cell capture from blood in metastatic cancer patients

open access: yesMolecular Oncology, EarlyView.
Pair‐wise comparison of the CellSearch and FETCH enrichment technologies for circulating tumor cells (CTCs) from metastatic breast, prostate, and small cell lung cancer patients shows an increased capture of CTCs using FETCH enrichment. The clinical implementation of circulating tumor cells (CTCs) as a predictive tool for therapy efficacy in the ...
Michiel Stevens   +6 more
wiley   +1 more source

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