Results 101 to 110 of about 1,636 (288)
Molecular Oncology, EarlyView.Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla +9 more
wiley +1 more source
Factorization of Dual Quaternion Polynomials Without Study's Condition. [PDF]
Adv Appl Clifford Algebr, 2021 Siegele J, Pfurner M, Schröcker HP.
europepmc +1 more source
Dual-quaternion backstepping control for a fully-actuated rigid-body [PDF]
, 2018 In this paper dual-quaternions are used to model a fully actuated rigid-body. A backstepping-controller that solves the trajectory tracking problem is derived and proved to provide uniform asymptotical stabilization of the error dynamics.
Raymond Kristiansen +5 more
core +1 more source
Molecular Oncology, EarlyView.Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch +13 more
wiley +1 more source
Molecular Oncology, EarlyView.Targeted therapy was evaluated in SHH medulloblastoma using neuroepithelial stem cell (NES) and tumor‐derived NES‐like (tNES) models in 2D monolayers and 3D spheroids. PI3K, AKT, and CDK4/6 inhibitors had minimal effects in NES but markedly reduced viability and growth and induced apoptosis in tNES cells, revealing distinct therapeutic vulnerabilities.
Monika Lukoseviciute +4 more
wiley +1 more source
Hybrid Dual Quaternion Algorithm For Precise Strapdown Inertial Navigation
, 2007 Dual quaternion is efficient methodology to express rotation and translation of the vehicles movements in the unified frame work. Recently, a strapdown inertial navigation algorithm based on dual quaternion was introduced. By comparing and analyzing the
유명종 +4 more
core
Molecular Oncology, EarlyView.We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric +10 more
wiley +1 more source
Dual Quaternion based Relative Navigation for Spacecraft Proximity Operation
, 2018 In this paper, dual quaternion based relative navigation in space environment for proximity operation is investigated. Dual quaternion is the parameter that can describe position and attitude in a unified form.
Na, YunJu +2 more
core
Hippo pathway at the crossroads of stemness and therapeutic resistance in breast cancer
Molecular Oncology, EarlyView.Dysregulation of the Hippo pathway drives nuclear accumulation of YAP/TAZ, activating stemness‐related transcriptional programs that sustain breast cancer stemness and fuel therapeutic resistance across subtypes, underscoring Hippo signaling as a targetable vulnerability. Figure created and edited with BioRender.com.
Giulia Schiavoni +11 more
wiley +1 more source
ISPRS International Journal of Geo-InformationThe comment disputes some of the inferences in the paper “Helmert Transformation Problem. From Euler Angles Method to Quaternion Algebra”, published in this journal. The key points in the dissent are the following: (1) The number of unknown parameters in
George Pantazis, Stefania Ioannidou
doaj +1 more source