Results 81 to 90 of about 994 (259)

Identification of a Shiga toxin A‐derived peptide internalized into Gb3 receptor‐bearing cells via interaction with the Shiga toxin B subunit

open access: yesFEBS Letters, EarlyView.
The process of internalization of the Shiga toxin A subunit via formation of a complex with the Shiga toxin B subunit, which specifically binds to the Gb3 receptor. The peptide is designed to act as a carrier of drugs into cancer cells. Here, we explored the potential of peptides derived from the catalytic A subunit of Shiga toxin (STxA) to be drug ...
Giulia Opassi   +6 more
wiley   +1 more source

Investigating transcription factor dynamics in health and disease using FRAP

open access: yesFEBS Letters, EarlyView.
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj   +3 more
wiley   +1 more source

Joint Stiffness Identification and Deformation Compensation of Serial Robots Based on Dual Quaternion Algebra

open access: yesApplied Sciences, 2018
As the application of industrial robots is limited by low stiffness that causes low precision, a joint stiffness identification algorithm for serial robots is presented.
Guozhi Li   +3 more
doaj   +1 more source

AscF in the mycobacterial CIII–CIV supercomplex lacks metal and nucleotide binding but links malate oxidation to respiration

open access: yesFEBS Letters, EarlyView.
The mycobacterial CIII‐CIV respiratory supercomplex is an obligate assembly, encompassing several subunits of unknown functions. We have characterized the intracellular subunit AscF, and show that it is unlikely to be a sensor for metals or nucleotides, but is required for growth on nonfermentable energy sources, and likely works as an adapter for ...
Eni Rile   +8 more
wiley   +1 more source

Study on a Twice Transfer Alignment Based on Dual Model

open access: yesDiscrete Dynamics in Nature and Society, 2015
This paper proposes a twice rapid transfer alignment algorithm based on dual models in order to solve the problems such as long convergence time, poor accuracy, and heavy computation burden resulting from the traditional nonlinear error models.
Shuai Chen   +3 more
doaj   +1 more source

An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes

open access: yesFEBS Letters, EarlyView.
GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg   +14 more
wiley   +1 more source

DUALS OF A FRAME IN QUATERNIONIC HILBERT SPACES

open access: yesPoincare Journal of Analysis and Applications, 2018
14 pages.
Sharma, S. K.   +2 more
openaire   +2 more sources

Dual-Quaternions: Theory and Applications in Sound

open access: yesCoRR, 2023
Sound is a fundamental and rich source of information; playing a key role in many areas from humanities and social sciences through to engineering and mathematics. Sound is more than just data 'signals'. It encapsulates physical, sensorial and emotional, as well as social, cultural and environmental factors.
openaire   +2 more sources

Dimethyl fumarate combined with cisplatin at subcytotoxic doses sensitizes cervical cancer toward ferroptosis and apoptosis through GSH restriction and p53 (re)activation

open access: yesMolecular Oncology, EarlyView.
Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano   +6 more
wiley   +1 more source

Factorization of Dual Quaternion Polynomials Without Study's Condition. [PDF]

open access: yesAdv Appl Clifford Algebr, 2021
Siegele J, Pfurner M, Schröcker HP.
europepmc   +1 more source

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